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Sarepta Therapeutics, Inc. Message Board

likeafox7210 208 posts  |  Last Activity: Feb 4, 2016 10:42 PM Member since: May 19, 2008
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  • Reply to

    Creatine Kinase Reductions

    by greyzone513 Feb 4, 2016 11:53 AM
    likeafox7210 likeafox7210 Feb 4, 2016 10:42 PM Flag

    Again, pure speculation and conjecture. CK is basically a measure of the ongoing infammation that happens regardless of activity level. Sure when the muscle is dead and replaced by scar and fatty tissue there will be no more CK to measure. Another sloppy example of the DNP's lack of knowledge regarding the pathophysiology of DMD. Man you have to quit believing everything the FDA feeds yo

  • likeafox7210 likeafox7210 Feb 3, 2016 7:59 PM Flag

    Cummings is a grandstanding moron. Look for is 5 minutes. I am fine with going after the gauges. For example BMRN and Valentin. Check their stock prices if you want a chuckle and no Farkas is on their case.

  • likeafox7210 likeafox7210 Feb 3, 2016 7:55 PM Flag

    Are you kidding me. All of BMRN's post hoc analysis was garbage. Both phase II trials failed ad did their phase III. The Frenchies arrogance was though was thought to win the day both by the charities and Dr F*chs cheerleading.

  • likeafox7210 likeafox7210 Feb 3, 2016 7:46 PM Flag

    I think you're right Thig. That BD could have been written by a 4th medical student or a first year resident. I would think she would be embarrassed that the BD was so poor. My guess is that Farkas has been given a earful and now it is up to them to figure a face saving way out. They must know our experts our loaded for bear. It surely will be fascinating how this plays out.

  • Reply to

    The smoking gun..............

    by stocktrooth Jan 29, 2016 11:48 PM
    likeafox7210 likeafox7210 Feb 1, 2016 1:38 AM Flag

    Tell that to the doctor taking care of your heart attack. I think he should give you a acetaminophen and call it a day. Whoops I meant aspirin but chalk it up to a busy day.

  • Reply to

    0.9%

    by luisxiao69 Jan 31, 2016 7:51 PM
    likeafox7210 likeafox7210 Feb 1, 2016 1:15 AM Flag

    Wrong again moron. Backers have 20-30% of normal dystrophin. Some more, some less. Why to you spread your freaking misinformation. You have been consistently wrong. I will give you credit for taking wrong facts and making them sound as the normal. Get a medical degree and stop spreading misinformation moron. You sicken me with your distortions. Just like your edict on steroid dosing. From now on My residents,fellows and me will be all over you like white on rice.

  • Reply to

    DMD Parent

    by pearsby09 Jan 31, 2016 7:07 PM
    likeafox7210 likeafox7210 Jan 31, 2016 10:29 PM Flag

    I agree with Pearsby. If a child care provider gets a whiff of the potential for child abuse he or she has a legal duty to report that individual to DHS. Not doing so puts the responsibility on the individual who failed to report. I am thinking it may be necessary to report this individual to DHS and let them investigate whether his boy is at risk. Yahoo would give up his IP address in a heartbeat. This man is beyond anger and bitterness. That is plenty to call in DHS.

  • Reply to

    LOA

    by speedbll Jan 31, 2016 12:39 PM
    likeafox7210 likeafox7210 Jan 31, 2016 9:55 PM Flag

    My guess is that you are no DMD parent but just an angry man, your previous post are full of bitterness. My guess is you are a short trying to come across as a parent that has found no satisfaction ever. If you are truly a parent I think you burned more bridges by you have all the answers and argumentative attitude. Unfortunately for you we haven't the time for a wacko dad but if your are a impediment to proper therapy DHS will remove your boy and place him in safer hands. I have seen this done more times than I can count.

  • Reply to

    LOA

    by speedbll Jan 31, 2016 12:39 PM
    likeafox7210 likeafox7210 Jan 31, 2016 9:45 PM Flag

    Actually it is Farkas that mush prove that there is a standard of care. I will tell you from my experience that every DMD boy is different. They are not little mechanical robots that all respond the same to conventional treatment. That is exactly why the FDA must be flexible. There is not one steroid dose that each boy must receive, not any amount of physical therapy, and as to TLC that comment is inflammatory and condescending to our European friends.

  • Reply to

    LOA

    by speedbll Jan 31, 2016 12:39 PM
    likeafox7210 likeafox7210 Jan 31, 2016 3:35 PM Flag

    You must be a very bitter man. It seems you would rather have no boys get a safe and effective drug. I am sorry about your boy!

  • Reply to

    LOA

    by speedbll Jan 31, 2016 12:39 PM
    likeafox7210 likeafox7210 Jan 31, 2016 3:08 PM Flag

    Truth, the normal dose of prednisone is 2 mg/ kg/ day. At this dose symptoms generally improve as does lab values like creatinine kinase and the sed rate. The next step is to to titrate dosage both by dose and duration between doses. The goal of doing this is to reduce the long term side affects of steroids. This is child dependent and not fixed in stone. Some will do well on once a day dosing. Others do well on every other day dosing, and a few can go longer than that. Remember if a boy is getting 40mg/day on a every other day regimen the dose would be 80 mg and so on. Again the goal is to use the least amount of steroids to control symptoms and lab parameters. A neurologist or pediatrician would know this. A non board certified ophthalmologist who likely has never managed a DMD patient I doubt he knows the intricacies of chronic steroid management in children.

  • likeafox7210 by likeafox7210 Jan 31, 2016 12:22 AM Flag

    Even the NBA gets the importance of a expert. Read the following quote about Cleveland's firing of Blatt.
    "I look at it like this: Say you had foot pain and you went to see a pediatrician rather than a podiatrist. The pediatrician, with his or her background in medicine, would perhaps be able to provide some sort of diagnosis. But wouldn't you want the expert? This experienced Cavs group needed an expert, not an NBA newbie."
    Hmmm...why doesn't the FDA get this basic premise. Farkas is no expert on a subject he pontificates about. Time for the FDA to get real!

  • Reply to

    The smoking gun..............

    by stocktrooth Jan 29, 2016 11:48 PM
    likeafox7210 likeafox7210 Jan 30, 2016 6:29 PM Flag

    That's not Stock misleading that is you and the FDA. I have decided that if Etep get approved it will be on the strength of SRPT's experts vs the FDA's resident poorly educated stooge. If our experts are the world leaders in the DMD space they should be able to school Farkas.. I tend to think they could embarrass the dufus to tears if they choose that route. If you all recall BMRN had no such experts so Farkas could get away with nonsense. Our experts are not going to allow him to BS his way through this Adcom. I suspect they will be more than prepared too shoot down any half baked statement he makes. That what gives me confidence that Etep will be approved. I can imagine these men and women salivating to decimate him. After all they aren't recognized as experts for nothing. What is Farkas claim to fame...absolutely nothing.

  • Reply to

    Still confused re Farkas' qualifications

    by kpr4444 Jan 26, 2016 8:01 PM
    likeafox7210 likeafox7210 Jan 27, 2016 12:06 AM Flag

    Medical Credentials are extremely important. Every physician is credentialed whether it be to get a license to practice, join a hospital staff, to qualifying to participate in a insurance plan to name a few. Credentialing is just a way of life for Doctors.

  • Reply to

    Adam Feurstein

    by qpoint617 Jan 26, 2016 10:18 PM
    likeafox7210 likeafox7210 Jan 27, 2016 12:00 AM Flag

    I believe your point is extremely valid. I haven't seen a real journalist tackle this subject but I don't think AF is your man.

  • Reply to

    ADCOMM: Patient Testimony #1

    by qpoint617 Jan 26, 2016 10:28 PM
    likeafox7210 likeafox7210 Jan 26, 2016 11:56 PM Flag

    Just curious. What is your profession or what do you do for a living?

  • likeafox7210 likeafox7210 Jan 26, 2016 7:51 PM Flag

    The last person I would pay attention to is AF. The fact that he even commented must have touched a nerve. Farkas made many outlandish comments in the BD not to mention poor data analysis. He need to be called out. I wouldn't be concerned but he lead the pack with the BMRN adcome. Do you really think he won't try the same for SRPT's adcom. If he were impartial then he wouldn't be getting the attention he is getting. Clearly he isn't our only bone of contention!

  • Reply to

    Farkas is Not board certified in Ophthalmology

    by starfe11 Jan 26, 2016 4:02 PM
    likeafox7210 likeafox7210 Jan 26, 2016 7:42 PM Flag

    It is possible that he may not even finished his residency in ophthalmology. The Board of Opthalmology wouldn't tell me. The medical board in Maryland did not answer. I sure it is still closed from the storm

  • likeafox7210 likeafox7210 Jan 26, 2016 4:15 PM Flag

    Prove your statement. How about a reference. You can't

  • Reply to

    Next Friday...

    by bionerd51 Jan 26, 2016 1:34 PM
    likeafox7210 likeafox7210 Jan 26, 2016 2:41 PM Flag

    Nerd OT. I checked with the American Board of Opthalmology and confirmed that Farkas is Not board certified in Ophthalmology. Do you know or does anyone know someone at the
    • Massachusetts Eye and Ear Infirmary, Boston, MA. To confirm that he even finished his residency in Opthalmology. Just being non board certified is bad enough but if he failed to finish would be a major blow to his credibility leading the DNP. Thanks!

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