I got trapped a few weeks ago answering his same questions over and over again then i stopped and now he is badgering everyone else. ...lol
Plyler was sure his friend was dying, so he grabbed the first dose of ZMapp. With no time to put on his protective suit, he handed the drug to a doctor who was already suited up. She connected it to an IV, which delivered the medicine directly into one of Brantly’s veins.
Within hours, Brantly grew stronger. However, another infected health-care worker, American Nancy Writebol, was in bad shape. Plyler split the ZMapp doses between them before both were flown to an isolation unit at Emory University Hospital in Atlanta, Georgia (see Airplane Biocontainment Unit, p 9). Emory is one of four hospitals in the U.S. with specialized isolation units designed for treating diseases like Ebola. ZMapp’s manufacturer sent additional doses to Emory so both patients could finish treatment. A few weeks later, Plyler got great news: Brantly and Writebol had fully recovered.
domestic manufacturers and produce larger quantities of Ebola monoclonal antibodies using tobacco plants or mammalian cells".
Cuban DR cured with zmapp
He showed symptoms of the disease on November 16 and was brought to Switzerland for treatment with the experimental drug ZMapp.
Established in 2012, BARDA’s Centers for Innovation in Advanced Development and Manufacturing are working to expand the production of Ebola monoclonal antibodies, like those in ZMapp.
BARDA is providing assistance to vaccine and therapeutic manufacturers to scale-up production from pilot scale, in which a handful of doses can be made, to commercial scale, producing millions of doses.
For Ebola immunotherapeutics, as previously mentioned, BARDA is supporting the development and manufacturing of Mapp Biopharmaceutical‘s ZMapp monoclonal antibody combination therapeutic candidate, which was provided over the past three months to several Ebola patients under emergency Investigational New Drug applications. That drug is currently being manufactured to provide sufficient doses for the initial clinical safety and efficacy studies in Ebola-affected countries in West Africa.
With funds from the President’s Emergency Request, we can expand production capacity to other domestic manufacturers and produce larger quantities of Ebola monoclonal antibodies using tobacco plants or mammalian cells.
NEW YORK (Reuters) - Two tiny companies are preparing to challenge some of the world's largest drug makers in the battle for dominance in the $3 billion global market for influenza vaccines, armed with little more than tiny tobacco plants.
"There's no way you can produce 50 million doses in 12 weeks" with current production technology, said Giroir. "But plant-based production could."
While one chicken egg can produce one or two doses of flu vaccine, one tobacco plant can produce 50 at a fraction of the cost.
Legislation that would add Ebola to the FDA’s Priority Review Voucher program cleared both the Senate and the House this week.
The Adding Ebola to the FDA Priority Review Voucher Program Act would provide a voucher for priority FDA review of a future drug to those who successfully develop therapies and vaccines for Ebola.
IBIO tech of choice and future