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Keryx Biopharmaceuticals Inc. Message Board

mgm2020 991 posts  |  Last Activity: 4 hours ago Member since: Mar 3, 2010
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  • Reply to

    Response

    by csanderson1805 Sep 13, 2014 11:48 PM
    mgm2020 mgm2020 Sep 14, 2014 9:19 PM Flag

    Since pima, or NUPLAZID, was given the possible designation of breakthrough therapy where no other treatment is available, the FDA will also review that and determine at the 60 day declaration if breakthrough designation will be granted. If it is then we will have an expedited review and it could be approved within 6 months of filing.

    Sentiment: Strong Buy

  • mgm2020 mgm2020 Sep 14, 2014 9:15 PM Flag

    I was responding to agas's post imbecile.

    Sentiment: Strong Buy

  • mgm2020 mgm2020 Sep 14, 2014 9:12 PM Flag

    That's pretty much what we have all been saying since the approval and unexplainable drop in the stock price. The "warning" IS inconsequential to the doctors that will still be prescribing ferric citrate as if the "warning" never existed because it is COMMON SENSE to them. Anyone with half a brain can see that this was never a "warning" issue but a very well orchestrated smear and fear campaign to take the price of KERX down. The market will catch on and again realize that this drug will alter the way dialysis patients(and possibly pre-dialysis) patients are treated for hyperphosphatemia---AND anemia-----and it's definitely a change for the better by lowering REAL RISK of infection and IV complications, improving compliance, AND lowering overall cost of treatment. Thanks for the posts jake.

    Sentiment: Strong Buy

  • Reply to

    Are shorts out of their minds?

    by juldocj Sep 14, 2014 6:38 PM
    mgm2020 mgm2020 Sep 14, 2014 7:51 PM Flag

    Have ANY analysts lowered their PT since the approval? I don't think so---and Roth RAISED their target to $32 from $30. Everything going on here is nothing more than scare tactics to separate you from your shares before they start going up again. Only ONE firm---FBR----that didn't even have an opinion on KERX until 2 weeks before approval and came out with a BOGUS report saying that there was a likelihood that ferric citrate wouldn't be approved(which proved to be VERY FALSE) had a $16 PT which was the lowest by far-----but somehow, THEY were the firm quoted in the AP article! Does that ring of BALONEY or what??

    Sentiment: Strong Buy

  • Reply to

    Ferric citrate sales

    by ktw518 Sep 10, 2014 7:22 PM
    mgm2020 mgm2020 Sep 14, 2014 7:46 PM Flag

    Why would the iron warning for dialysis have an impact on CKD? These patients are not generally not on IV iron and have their anemia treated differently. We will find out if the ferritin levels reach any level of concern when the P3 data is released down the road. Hopefully they are running concurrent trials using different dosing levels of zerenex to predict ferritin and TSAT change. But I do not believe the P2 CKD trial raised any flags as far as the "iron overload" issue that is ONLY an issue if the patient is also on IV iron. And a lower dose MAY control iron levels, anemia, hemoglobin stasis, AND lower FGF-23 levels(if this is being evaluated also). JMHO MGM

    Sentiment: Strong Buy

  • Ron Bentsur discussing the OLE study results with patients on Zerenex for up to 2 years-----you will also read that IV iron was PROHIBITED for anyone with a ferritin level above 500:

    "I will now briefly speak about our ongoing open label extension study in dialysis. As a reminder, this open label extension study is not a regulatory requirement and is expected to be completed in the second quarter of this year. Importantly, this study provides us safety and efficacy information for Zerenex for up to two years of exposure and notably for the preliminary data cut off that we were reported on last November, serum phosphorus appears to be well controlled, ferritin and TSAT go up and plateau with ferritin starting to come down slightly after week 36.

    In addition, with IV iron use prohibited in the study as long as ferritin is above 500 or TSAT is above 30, as of this preliminary data cut off the IV iron use in the study appears to be very low with close to 70% of the patients not receiving even a single dose of IV iron and the use of ESA also appears to be considerably lower than the national average, and this while hemoglobin is being maintained. In summary, we believe that this preliminary data reinforces the long term Phase 3 data and the notion that Zerenex can potentially eliminate IV iron use in most patients for extended periods of time, lower ESA use and maintain hemoglobin."

    Sentiment: Strong Buy

  • mgm2020 mgm2020 Sep 14, 2014 6:21 PM Flag

    here is a clip from the long term P3 results taken directly from the PR:

    "Zerenex Administration Over 52 Weeks Increased Iron Stores
    In addition, approximately seventy percent of dialysis patients are truly or functionally iron depleted, suffer from anemia and require treatment with IV iron and/or ESA injections. The newly published clinical trial results show that, in addition to its efficacy as a phosphate binder, Zerenex also significantly raises iron stores as measured by serum ferritin and TSAT.

    The results showed Zerenex demonstrated a statistically significant treatment difference versus the active control group in mean change in serum ferritin (+306 ng/mL vs. +19 ng/mL) and TSAT (+8% vs -1.2%) from baseline (day 0) to week 52. In the PERFECTED study, subjects randomized to receive Zerenex required significantly lower dosages of IV iron and ESA; and hemoglobin levels were higher in Zerenex treated patients than in those receiving active control.

    The investigators cited an analysis of the trial results that indicated that the projected reduction in the need for IV iron and ESA use would result in significant pharmaco-economic benefits. In addition, the investigators wrote, "one would postulate that decreased IV iron and ESA usage could result in decreased nursing time to administer IV medications which could be redirected to other aspects of patient care and decreased risk of infections due to fewer IV injections." In the PERFECTED study, fewer serious adverse events (SAEs) due to infection were seen in the subjects randomized to Zerenex compared to active control."

    SIGNIFCANTLY LOWER DOSES!! Stop lying and read the data.

    The authors noted that, if approved, Zerenex would be the only phosphate binder that also increases iron stores and decreases IV iron and ESA use.

    Sentiment: Strong Buy

  • mgm2020 mgm2020 Sep 14, 2014 6:12 PM Flag

    Spill is obviously posting from prison where he is someone's b-tch--that's why he is so full of hate, Probably beats his kids and his wife too. He has NEVER been right about KERX yet---and his record will remain intact. The CKD study has iron and hemoglobin as the primary and secondary endpoint so it is not going to be considered as a binder but an anemia treatment. And no need to worry about iron overload since these people are not on IV.

    Sentiment: Strong Buy

  • Reply to

    Stop Replying

    by twincathy00 Sep 13, 2014 10:13 AM
    mgm2020 mgm2020 Sep 13, 2014 12:57 PM Flag

    Thanks for your appreciation. I have a small private office and see anywhere from about 8 to 20 patients per day. That does leave me with a nice amount of free time. I also don't start until 12 3 days/week and am off on Wednesday. So I really can post just about any time it strikes me except when I am actually face to face with a patient. You would think I was supposed to be seeing patients on an assembly line the way some people criticize me.

    Sentiment: Strong Buy

  • mgm2020 mgm2020 Sep 13, 2014 12:32 PM Flag

    They all think they are geniuses because the stock price fell after approval. No one was predicting that. The only reason anyone made any references to the price dropping was IF the launch was not a success-----not because of a contrived campaign to malign the company, the drug, and the stock because the FDA decided to list the greatest BENEFIT of ferric citrate on the label as a "precaution" which is common sense to EVERY PRESCRIBING doctor and will deter no one from prescribing it. The launch will be highly anticipated, hopefully the new name will be unveiled shortly---but I like ferriplex, and if we get any advanced word of ferriplex being added to insurance panels prior to launch that will also boost the stock. Enjoy your weekend.

    Sentiment: Strong Buy

  • mgm2020 mgm2020 Sep 13, 2014 12:26 PM Flag

    That should read UNEDUCATED before LYING.

    Sentiment: Strong Buy

  • by replying to all of the ignorant, bashing, brainless, insulting, worthless, asinine, rude, enducated, lying and deceptive pieces of garbage on this MB and at least FOR THE NEXT MONTH I will not respond to them---either directly or indirectly. The problem is, that when I don't post or respond then they post that I have left the board and abandoned the stock. That will not be true and I will keep posting positively, as is warranted. The stock will return in price, the RX numbers and sales from Japan will increase dramatically, the sentiment will begin to turn, and the launch of ferric citrate following it's MONUMENTAL APPROVAL with a "precaution" that insults the doctor's intelligence that will be prescribing it----will be surprisingly strong. Now---if anyone else cares to respond to the cowardly cockroaches---BE MY GUEST. GO KERX, GO ACAD, GO IDRA, and GO ISIS.

    Sentiment: Strong Buy

  • mgm2020 mgm2020 Sep 12, 2014 6:34 PM Flag

    Go back and read the P3 trial results because you are completely wrong-----the iron impact of ferric citrate improves and enhances red blood cell production, which is why many patients can be taken completely off their EPO. Why are you still posting the same negative garbage that is also incorrect? You TRY to sound intelligent but you are posting to longs here who know these results inside and out. And the ferritin levels plateaud at week 36 and then DROPPED during the remainder of the study----which has been ongoing now for 2 years------and not a SINGLE CASE of IRON OVERLOAD!!

    Sentiment: Strong Buy

  • mgm2020 mgm2020 Sep 12, 2014 6:26 PM Flag

    All of the bashers always seem to forget that medicine is about PROGRESS---and that progress allows for the engineering of safer and less toxic or even non-toxic compounds. That is how nearly ALL of the cancer therapies started out---with extremely high toxicity levels, and now they are much more precisely targeted. Same with MS---extremely toxic compounds at first and now----maybe an allergic reaction here or there, but the vast majority of patients tolerate the therapy very well and show tremendous progress. ISIS will flourish the same way.

    Sentiment: Strong Buy

  • mgm2020 mgm2020 Sep 12, 2014 2:36 PM Flag

    It's not just this board---it is the entire market! I had a friend text me saying that the warning was really bad. I said I thought he was smarted than that, and that the warning was nothing since the doctors already check iron levels and will take their patients off IV iron. WHERE ARE THESE PEOPLE'S BRAINS??? Same thing with Oliviero's "sale" which was an AUTOMATIC TAX SALE and would have occurred regardless of price, "warning" or if the stock was $10 or $30!! The selective ignorance is amazing!

    Sentiment: Strong Buy

  • mgm2020 mgm2020 Sep 12, 2014 1:20 PM Flag

    Why don't you be a man and not a coward hiding behind a new screen name and let us all in on who you were before you started posting with another new ID? There are only a few IDIOTS that would post like that and you have to be one of them. Which IDIOT are you? And you're right-----EVERYONE that listened to me PUMP KERX since I got in at $6.25 LOST MONEY---right? Everyon that BOUGHT on the dips when sentiment was terrible and I kept saying the stock would go back up LOST MONEY---right? Everyone that listened to me saying that there was NO WAY this drug wouldn't be approved was DUPED--right? What have I missed? And I will state that the stock is going to go back up from here and ferric citrate will be a huge success. We'll see how that pans out I the future---but that's what sock investing is all about. Now---you can say that I ws wrong about the stock price following approval----but no one could have predicted the blatant manipulation that took place----but now seems to be ending. YOU are just another vapid, brainless poster that ONLY comes on the MB to post a worthless reply regarding a post of mine----and there are only a few of you IMBECILES around-----so just let us know which imbecile you are.

    Sentiment: Strong Buy

  • It's not going to get any better than this if you are buying or looking to buy. Higher lows and increasing prices during the day(from the bottom) and a very nice recovery yesterday. This will be the trend for the next few weeks with higher lows as the shorts are pretty much exhausted and need to let the stock climb back up---AND the launch of ferric citrate is approaching. Roth INCREASED their PT to $32 and Brean reaffirmed, both saying that the label was merely a common sense alert if patients are already on IV iron------and nothing more. And as I have said-----the "warning" is an insult to the doctor's intelligence who will be looking forward to presenting this drug to their patients as a BETTER ALTERNATIVE to what they are currently on and prescribing it for it's enhanced benefits, lower overall cost, and fewer side effects. The rebound will continue and strengthen.

    Sentiment: Strong Buy

  • Reply to

    ISIS' is above the upper Bollinger Band,

    by casemarinecal Sep 12, 2014 9:58 AM
    mgm2020 mgm2020 Sep 12, 2014 10:53 AM Flag

    The only Bollinger band the stock is above is the 10 day band, which is not significant. It I still within the 6 month and 1 year bands. Many analysts say the best time to buy a stock is when it is moving the upper band higher and riding it up. That is a very bullish sign, and ISIS will begin to do that. Still 40% below the 52 week high, milestone payments coming, 34 programs in development and trials right now------and a PRIME TAKEOVER TARGET in the product and revenue hungry biotech and pharma arena.

    Sentiment: Strong Buy

  • mgm2020 mgm2020 Sep 12, 2014 9:49 AM Flag

    You know how many MB trolls were on the ACAD board over the last 2 weeks saying the same things you are? And ACAD was also spotlighted with ISIS----and where are all of the bashers and shorts now??? Exactly where you will be shortly-----GONE! SO why don't you save yourself the trouble and pain and just get lost now.

    Sentiment: Strong Buy

  • Reply to

    new brand name

    by hooclaus Sep 12, 2014 9:38 AM
    mgm2020 mgm2020 Sep 12, 2014 9:42 AM Flag

    I think ferriplex is a good name.

    Sentiment: Strong Buy

KERX
13.69+0.14(+1.03%)Sep 17 4:00 PMEDT

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