I am not any good at reading tea leaves. Looks like it has basically stopped trading. What does this indicate(besides that no one is buying/selling)? Stability-standoff-bottom-top-early lunch??
Applicants: ANAVEX LIFE SCIENCES CORP. [US/US]; 51 West 52nd Street 7th Floor New York, NY 10019 (US)
Inventors: MISSLING, Christopher, U.; (US).
DURRANT, Cameron; (US)
Agent: SAUNDERS, Thomas, M.; Novak Druce Connolly Bove + Quigg LLP 100 Cambridge Street, Twenty-first Floor Boston, MA 02114 (US)
62/065,833 20.10.2014 US
Title (EN) A 19-144, A2-73 AND CERTAIN ANTICHOLINESTERASE INHIBITOR COMPOSITIONS AND METHOD FOR ANTI-SEIZURE THERAPY
(FR) A19-144, A2-73 ET CERTAINES COMPOSITIONS INHIBITRICES ANTICHOLINESTÉRASES ET PROCÉDÉ DE THÉRAPIE ANTI-CONVULSIVANTE
Abstract: front page image
(EN)This invention concerns a dosage form comprising a therapeutically effective amount of A19-144 or A2-73 and a therapeutically effective amount of at least one AED. This invention further encompasses a method of treating a subject in need of such treatment comprising administering a therapeutically effective amount of A19-144 or A2- 73 in conjunction with an therapeutically effective amount of an AED.
(FR)La présente invention concerne une forme posologique comprenant une quantité thérapeutiquement efficace d'A19-144 ou d'A2-73 et d'une quantité thérapeutiquement efficace d'au moins un agent anticonvulsivant. Cette invention concerne en outre un procédé de traitement d'un sujet ayant besoin d'un tel traitement, comprenant l'administration d'une quantité thérapeutiquement efficace d'A19-144 ou d'A2-73 conjointement à une quantité thérapeutiquement efficace d'un agent anticonvulsivant.
big...me either I am just annoyed and curious as to just what is their motivation. Are they really trying to bring down a small company working to treat a scurge of a disease? I mean really? Somewhere in the pile of worthless human being activities (near the bottom) we should find these guys.
"perfectly positioned as just another pump and dump that will likely have little to no residual equity value as the story plays out."
Considering all the sub micro..mini me...micro bios out there w/uUUUgatz to offer, why are they obsessing here? What the hell are they afraid of? What #$%$.
Agree, If Dr M has made this kind of observation then he will recognize that although the science must be proven in endless, expensive testing an even better outcome is for patients to begin to function normally, to recover. Yes, the science must be done, analysis must be executed and exhaustive trials must be completed, that is how we do things till now. Unless, A2-73 makes the empirical case that it just works as an effective treatment, then a lot of $$/time will be saved. I expect something like this soon, certainly long before the endless(yada-yada) trials are done.
More reality in trials and people who are impacted directly. Not an obtuse-mumble-jumble interview. I think there are parts of the world where people lie as a matter of normal conversation if there is any money at stake. Places where you cannot believe one word not one record, document, certificate of authenticity, nothing is credible. My limited exposure to Aus. is they are honest and direct as a cultural norm. I am willing to accept the interview as evidence that what is being described could be true, as opposed to anything from China which I would have the opposite bias based on many years experience. There it is then, another anecdote, we could just as easily have one that says the whole thing is a farce.
We understand this is a risky investment. We also understand that risk is mitigated by information and by knowledge to apply what we learn. Trials data, pt's interviews, progress anecdotes, scientific evaluations, peer reviews all matter and sadly take forever. But, having a patient recover their mind/life is like having the blind recover normal vision, or a severed spinal cord patient get up and walk away, or a dear child w/autism rejoin their family. The risk of investing here is very high but the rewards may be worth it. Cannot happen soon enough for me which is why legitimate anecdotes help..
can not say from this , the thought suggests itself.But, we do not know.
another anecdote. Sounds like they are getting impatient with the glorious clinical trial process and all the REALLY BIG thinkers...HUH a rowdy bunch in Austrailia
Source: Xinhua 2016-04-29 10:22:40 More
MELBOURNE, April 29 (Xinhua) -- Australia will be the site of a world-first drug trail attempting to slow the onset of Alzheimer's disease by as much as a decade.
In what is being described as the "world's largest drug trail," Melbourne University has called on 600 healthy adults - who don't have any memory problems - aged 65 to 85 to volunteer for the first stage of the A4 study.
Early participants in the study will undertake a brain scan to determine if they have amyloid plaques, a sticky build-up which can accumulate on nerve cells around the brain.
Laureate Professor Colin Masters, from the University of Melbourne and the Florey Institute, said scientists believed the presence of amyloid plaques was a key reason some people developed Alzheimer's, a debilitating brain condition which affects memory.
"This is the first groundbreaking study to demonstrate whether we can delay onset by several years, at least five or 10 years," Masters, who will lead the Australian leg of the U.S.-based clinical test, told News Corp on Friday.
"This is the first attempt at stopping the disease before it starts and before it progresses to full blown dementia."
Only around 100 participants who show high levels of the substance will take part in the main study, which is set to begin returning results in 2020.
"In old age there appears to be a failure of machinery to get it out of the brain," Masters said. "This is the principal, underlying mechanism which causes the brain to degenerate."
Medical science has only been able to detect the presence of amyloid plaques in their early stages for the past few years.
"We can pick it up 10, 20 years before the onset of memory loss," Masters said.
"What we're trialling now is using an antibody and other drugs to help get (the amyloid) out of the brain."
The 100 study participants will be split into two groups, with half receiving a promising new anti-amyloid drug and the remainder a place
S/price action today has nothing to do w/science or results...these are the typical parasites who show up to see what they can infest...and who add zero value...kind of like politicians
Massive on the huge scale...w/Pfizer likely lead...added value w/A2-73/Viagra combo...standby for product naming contest....