Yeah, Hitler was passionate about what he was doing too. If your "passion" is destroying something and bringing others down, what good is it? If your "passion" only hurts you, fine, you have that right. But don't go around trying to pretend your "passion" is good for others when it's obviously destructive.
Dan, it's funny how after the Presidential election in which President Obama won a second term in a huge landslide, the GOP decided to distance themselves from the loser Tea Bags. Then, a couple months ago they decided to let them back on board-Palin rehired at Faux etc. Now, they are all slamming Cruz and his tactics that are bringing their party down again, while Palincomparison embraces doofusy Ted Cruz. The GOP would be doing themselves a big favor to distance themselves from these anti-American so called "patriots" once and for all which would bring independents and moderates back into their party to make it strong again.
hey longhorn, despite your constant yahoo i.d. name changes, your closeted gay fantasies keep rearing themselves every time you make a comment here, exposing who you are every time....The only thing that surpasses your stupidity is your blatant sexual frustration. PS, I didn't know "hutspa" was a synonym for complete egotistical loser. WOLF? More like the squealing of a mouse caught in a trap. LOL. Apparently my running of my "big fat strap(?)" had A LOT of MEANING and it got under your see through skin to the "nth" degree. LOL. you dope. LOL.
The threat of shutting down the country has already lead to uncertainty on Wall Street. Last time these fools pulled this stunt America's credit rating was lowered. Someone, anyone please tell me what is "Patriotic" about doing things that HURT this country. Anyone? There was an article in GQ about Cruz, and it wasn't about his modeling career. The guy is an egocentric self-absorbed fool who is more interested in showboating than he is in the overall well-being of The United States of America. Tea Party "Patriot"????? Really? No, these people are traitors to America.
What is with the endless, useless comments by this MotherlessTheresa fool. Hey idiot, could you try to keep maybe HALF of your stupid comments about ACTC? Either that or seek psychiatric help and medication.
Disease Indications Including Using Pluripotent Stem Cells.
MARLBOROUGH, Mass. — September 19, 2013 – Advanced Cell Technology, Inc.(“ACT”; OTCBB: ACTC), a leader in the field of regenerative medicine, announced today that it has filed an Investigational New Animal Drug (INAD) application with the Food and Drug Administration (FDA) to test its proprietary "off-the-shelf" mesenchymal stem cells (MSC) in a range of different disease indications.
The studies will evaluate the safety and efficacy of ACT's pluripotent stem cell-derived MSCs in ten spontaneous disease models in dogs, which are similar to various human inflammatory and immune-mediated diseases. While these companion animal studies represent research intended for ultimate licensure of veterinary therapeutics, ACT anticipates that the trial results may be relevant to its path to clinical trials in human patients and may provide a more robust assessment of safety and therapeutic endpoints than what can be obtained from inbred rodent models. The INAD is directed to ten canine disorders corresponding to hepatitis, glomerulonephritis, osteoarthritis, Crohn's disease, inflammatory bowel disease, spinal cord/disc disease, meningoencephalitis, hemolytic anemia, pancreatitis and sepsis.
"This INAD filing extends our ongoing work with world experts in veterinary and regenerative medicine," said Robert Lanza, M.D., chief scientific officer of ACT. "Preliminary studies in rodents have shown that our hESC-derived MSCs possess unique biological and therapeutic properties, and can dramatically impact a spectrum of diseases ranging from lupus to multiple sclerosis. In addition to veterinary applications, these large animal studies may help inform and optimize subsequent human clinical trials that the company may pursue. We believe the etiology and system-wide effects of naturally-occurring diseases in large animals, such as dogs, provide an excellent model of human conditions."
ACT's proprietary MSCs have been extensively characterized both in vivo and in vitro, and their effects have been shown to be superior in animals to those of their bone marrow (BM)-derived MSCs counterparts. ACT's proprietary MSCs are immunoprivileged and therefore, may be used "off the shelf" in a wide range of clinical indications. In addition to increased efficacy, hESC-MSCs can be expanded to large numbers in vitro (approximately 30,000 times greater yields per unit than adult BM sources). Since MSCs are derived from an inexhaustible starting stem cell line, the cost and regulatory burden of requiring many donors is thereby removed, as is the case with the adult sources of MSCs currently in the clinic. Having a single, donor-less source of pluripotent stem cells for manufacturing MSCs also removes the batch-to-batch variability in potency and the risk of communicable diseases that comes with relying on bone marrow or other adult tissue donors in the current MSC setting.
"The preclinical studies that Dr. Lanza and our team have carried out can now be translated into companion animal studies and, hopefully, human clinical studies in the not-too-distant future," said Gary Rabin, Chairman and CEO of ACT. "In addition to advancing our corporate strategy to apply our cutting edge stem cell technologies to bring human therapies to market, this step into companion animals also elucidates new potential market opportunities for our company. The veterinary market is a large and exciting market in which we may have a significant opportunity to apply our leadership in regenerative medicine. The development of these therapies may permit veterinarians and pet owners to manage pets' medical needs safely and effectively, and could result in longer and improved quality of life for pets."
Yeah, the GOP has tried their damnedest to spread propaganda via FAUX News and the millions dollars a year Limpbone and the rest of the over stuffed clowns. The Republican dominated media, you know the ones, Palincomparison referred to them as the "drive by media" has a stranglehold on what Americans hear. That's why the GOP tried to defund PBS, because PBS wasn't beholden to corporate advertising dollars and could actually put out truly informed programming. That was a huge threat to the vast right wing conspiracy. Once the Obamacare laws get implemented there will be no turning back and we will move forward so we can get OFF the list of the worst cared for citizens on the planet.
Really Prober? That's funny because all you do is #$%$ and moan and complain about this country now. I guess you should "leave it" huh? Either that or turn back the clock to a time when you didn't have to pretend you actually had something worth taxing, and spent your days draft dodging instead of sitting on your can blabbing on a penny stock blog. What an idiot.
Yes notthat, Texas is one of the biggest drains as far as states go on the U.S. Economy. They get so much in tax giveaways and they don't pay nearly as much in as they get. Let them handle their own debts for a change.
Hey, the right wingnuts can't help it. They tune into Faux News and gobble up all the racist anti-American tirades and then like mother Robins turn around an puke that garbage onto anyone within earshot. They can't think for themselves and they are so scared now that they see they as white men will no longer be the majority in this great country of ours.
Hey #$%$, they only thing sad on here is you. You are pathetic and a lousy excuse for an American.
Lonesome, you're another fool. The only Gestapo was you man Bush and Cheney who lied, cheated and stole all in the name of "Patriotism". We as a country are still trying to recover from their stupidity (ignoring the 911 warnings one month prior, Cheney revealing names of CIA members, Cheney meeting with the oil companies in secret, Cheney hiding in a bunker on 911 while the rest of us were above ground and vulnerable) but oh yeah, all that #$%$ about "support our troops" and "don't criticize the president". Hey, where did all you friggen flag wavers go anyway? You all have such anti-American sentiments these days you FOOLS. LOL. Go ahead though, that's why you keep losing, traitors !!!
No one gives a damn what you believe #$%$. You're just a douchebag white racist who is afraid to let go of the past and let progress take over. It's OK though, it will happen whether you want it to or not and you'll be left with your sad bitter party to comfort you. LOL Go away fool ...
#$%$ pipes up again. Was this before the 5 shots of Bourbon? Simmer down big guy, no one gives 2 sh'ts what you say but I'm having fun with your stupid A today for sure. DUMAZZZZZ
I'm afraid we're stuck with them, besides it's not the entire state-just a few rich aholes who haven't go a clue and probably never fought to protect this country. Chicken hawks like CHENEY.
Oh, there's the highly moral and sane #$%$ passing judgement again. Wow, you never cease to bore me #$%$ What a dud. Go back to sleep.
Yeah, for once I'd love to see ol' Jorge W. Bush having to work for the Mexicans instead of the other way around. Let him get paid peanuts for working his A off. Oh wait, I AM talking about G. W., and him working his A off? That'll never happen. LOL
No, your not Democrat or Republican, yeah right. You're just an idiot I guess.
slurpin' down the ol' Bourbon so early in the day #$%$? IF? GUTTY? LOL LOL LOL. Brilliant !!!! Wow are you deep !!! LOL LOL LOL What an #$%$.