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Trius Therapeutics, Inc. (TSRX) Message Board

nowwhat654 37 posts  |  Last Activity: Oct 11, 2014 3:54 PM Member since: Jul 13, 2012
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  • nowwhat654 nowwhat654 Oct 11, 2014 3:54 PM Flag

    I'm very much hoping that "Turtle will have the last laugh and your mockery will haunt you"!!!

    Info from trials either blinded or Open (like Direct) generally leak like a sieve and tutes get on-board. Very high Tute ownership BIO stocks that POP generally have 70%+ ownership. It's because tutes generally are very well connected and know how to make money.

    It doesn't seem like this is happening with NWBO, even with the "open label" trial of direct. I'm pretty sure the last cash raise the financing company did DD with MD Anderson before they demanded free warrants and subsequent unloading of the stock, just like the last cash raise they did. (I'm guessing they bought quite a few puts right before they started ditching the newly acquired stock (look at put options in OCT).

    And the NAT GEO guy was not televised on Stand up Cancer. It was a video on NAT Geo's web site. I watched it hoping for some air time that didn't come (why wasn't he on the show if NWBO is so promising?).

    Given all the info you shared along with everything else "retail" stockholders pump, why is it that the share price continues to decline and the Tutes invest elsewhere if it's such a promising technology?

    And yes, I'm underwater like everyone else so I'd like to reverse this trend as well, I just don't know what it's going to do it. And don't say it's because it's a "phase one" trial. Look at what happened to SRPT with phase one few months ago, also just under 70% tute ownership....

    My gut is telling me something is wrong, I just hope my gut is wrong.

  • From all the "striking results" and owning NWBO stock?

  • nowwhat654 nowwhat654 Oct 11, 2014 10:45 AM Flag

    It would be nice but it won't happen.

    You will get to hear some words that sound like "striking results"

  • nowwhat654 nowwhat654 Oct 10, 2014 8:28 PM Flag

    "DILUTIONS under not so favorable terms or OUT OF BUSINESS"

    I agree with # 6 however, if Direct was showing tumor regression in phase 1 as per the slides Powers likes to show on what happened to mice, this stock would not have slid to 4 bucks. The only tid bits we have (and I don't know if it's the same guy) but the Nation Geo guy from Canada and the one case that started the MD Anderson/AF debacle. That is the only glimps into the COMPLETELY OPEN LABEL TRIAL.

    Published results the only thing going to save this stock. Powers has stated she wants to start a phase 2 PRIOR to the Direct results. If she does this, Why is the big question mark I have. And the answer I'm guessing is going to be to keep "hope" alive and retail buying in on "hope". Positive results from Direct need to be published or this stock will go back to penny land. (it technically still is as NWBO did a reverse split of 16 to 1, which would put today's price at .25 prior to the split.

  • nowwhat654 nowwhat654 Oct 10, 2014 6:48 PM Flag

    Really? I'm the dumb one? You are underwater on your shares (as well as I am on options) and it seems you are basing it on "hope" to make your money back or are being paid by NWBO to post on these boards.

    I have listened to the webcasts. Maybe Linda didn't share those webcasts with those who were financing the last 2 deals which is why those terms were so poor... They should listen to webcast I guess...

    So you believe Powers is sandbagging the results from Direct in order to get poor financing deals? If the results were stellar or "striking" as Powers would put it, there would people lining up to buy discounted share blocks. So why do you think that is? No one but retail investors has listened to the webcast? Is that what you think?

  • nowwhat654 nowwhat654 Oct 10, 2014 6:28 PM Flag

    "Only the shareholders are blinded"

    It freaking sure seems that way.

  • nowwhat654 nowwhat654 Oct 10, 2014 6:19 PM Flag

    Well, to further your point, the Direct trial is open label, started 18 months ago and the last patient was 6 weeks ago. Do you really think the CEO (Powers) doesn't know how the unblinded open label Direct tria is doing that NWBO is funding?

    The last two increasingly poor terms on the latest cash raise does not give me confidence that Direct is working like she had hoped.

  • It's been over a 18 months now since the trial started, Power's herself stated the response will been known quickly and since it's an open label phase 1, it's not blinded.

    So who here thinks Linda knows no more than anyone else on these boards about Direct? I personally think she knows everything (and why wouldn't she? It's open label and she is the CEO funding the trial). Why also do you think we have had 2 cash raises in a few months and very poor terms.

    Why do you think that is? I'm not bashing, but the stock price has been on a downward spiral and something tells me Direct isn't the end all we are hoping for.

  • nowwhat654 nowwhat654 Oct 10, 2014 5:44 PM Flag

    well, lets hope he makes it. hard to tell currently if it's the transfusion, the "drugs" or both together that had the positive response to those who survived. The billion dollar question is if Duncan would have survived had he be given the drug within the first couple of days.

    We will know in a couple of weeks after testing if CMRX's drug can work alone or not. I'm sure they are doing testing on primates as we speak. If it's proven to work alone (within an acceptable time frame from diagnosis, not 2 weeks later) things are bound to look very "up" for CMRX as their drug is the best choice due to ease of administering/storing and transporting it. On the flip side, it could be the antibodies that are saving these people, but I don't know if antibodies can be mass produced.

  • nowwhat654 nowwhat654 Oct 9, 2014 8:21 PM Flag

    "there are trials with "striking results" all the time that catch the market unawares"

    True, very true. Most all of them have a couple of things in common that NWBO seems to lack. 70+% tute ownership and a market cap north of 500 million when it happens.

    NWBO has almost zero tute ownership, 8 people working there and a CEO who likes to use the word "striking" without anything to back it up. If the results from Direct are ever made public and they are "striking" I will gladly eat my words and gladly watch my account balance spike. But for now, all I have is "hope" and a diminishing value on my NWBO stock.

  • nowwhat654 nowwhat654 Oct 9, 2014 7:52 PM Flag

    I think it's because what he wrote this time is actually spot on. I'm not bashing and I'm long on call options, but with all the people involved in the clinical trials, it would be difficult to keep "striking results" hush hush and funds would be falling over each other for discounted shares.. which isn't happening.

  • Reply to

    SCIENCE and FUNDAMENTALS have NOT CHANGED

    by turtle065 Oct 9, 2014 4:47 PM
    nowwhat654 nowwhat654 Oct 9, 2014 7:46 PM Flag

    I've done a fair amount of reading on DC cells and the potential they may have. In theory NWBO may be on to something but they haven't shown ANYTHING that it works other than the words "striking results".

    Why do you think each financing deal is worst than the last one? If NWBO was holding the "cure" like I would like to believe, word would be out and people would be begging to give them money for discounted shares.

    The Direct trial has been going on for well over a year now, it's open label so everyone knows and can talk about the results they are seeing. Given the recent financing "deals" my guess is results aren't as "striking" as Powers wants everyone to believe, which is why -L increased it's size and Powers wants to start a phase 2 with Direct BEFORE results are even published for the phase one.

    Powers may be able to pull a rabbit out of a hat and surprise everyone with her mixture of "special sauce", but I think there are too many people running the trials to keep "striking" results under wraps.

  • Reply to

    SCIENCE and FUNDAMENTALS have NOT CHANGED

    by turtle065 Oct 9, 2014 4:47 PM
    nowwhat654 nowwhat654 Oct 9, 2014 5:18 PM Flag

    Just curious, but can you elaborate on "NWBO SCIENCE IS STRIKINGLY POSITIVE !!!!!!!"

    NWBO hasn't really shared any "science that is strikingly positive" other than a very old study for -L and one brief case of Direct which is an open label study and has already treated everyone enrolled.

    So until Direct results come out and come out very positive showing NWBO is the real deal, I'm afraid this will continue to slide back into penny stock land with no results, the continuing erosive share price and even worse financing deals.

    I'm long options which are now out of the money.... and I'm tired of Power's using the word "striking" without anything to back it up.

  • Reply to

    Something is very wrong

    by nowwhat654 Oct 9, 2014 10:29 AM
    nowwhat654 nowwhat654 Oct 9, 2014 10:49 AM Flag

    "Do you know the clinical trial is blinded"

    Do you really think Doctors are idiots and are unable to tell if a patient is responding to the drug or to placebo?

  • nowwhat654 by nowwhat654 Oct 9, 2014 10:29 AM Flag

    If Direct was working, don't you think the Doc's at Anderson would be blabbing their mouths? What about the GBM Doc's? The only blabbing we get is Powers stating "striking results" without presenting ANY striking results.

    I'm long (on options) but this stock wouldn't drift down like this if in fact it was working. At least that is my opinion.

  • Reply to

    Confirmed. Robert Demeger passed away.

    by rrrichmond Oct 6, 2014 9:06 AM
    nowwhat654 nowwhat654 Oct 6, 2014 5:24 PM Flag

    Seems that this is true. Guy didn't even make it year.

  • Reply to

    Interim analysis - DcVax-L

    by anotherday1225 Oct 2, 2014 1:05 PM
    nowwhat654 nowwhat654 Oct 2, 2014 5:01 PM Flag

    I think it's 88

  • nowwhat654 nowwhat654 Oct 2, 2014 4:39 PM Flag

    Wow, if this is true, you are going to make a lot of money or look back at what a bad idea this was.

    I'm long, but have my doubts (won't give numbers on enrollment for L, little info on direct which is open label of all things, MFG is very "expensive" given the size of the current trials).

    I'm hoping NWBO pulls a live rabbit out of the hat.. but that's all Power's is giving investors is hope instead of clinical results...

  • stellar direct results if they ever publish them.

  • nowwhat654 by nowwhat654 Sep 26, 2014 10:40 AM Flag

    that is the fork that kills this... another study needs to be done

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