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Osiris Therapeutics, Inc. Message Board

oldfolks95610 21 posts  |  Last Activity: Sep 29, 2014 10:28 PM Member since: Dec 27, 2006
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  • oldfolks95610 by oldfolks95610 Sep 29, 2014 10:28 PM Flag

    Released good data from trial today to expand usage of already approved drug and dumped 7 %.
    "That said, we do have this from Needham and Co." "This morning Seattle Genetics reported positive top-line data from the pivotal AETHERA trial of ADCETRIS. The trial met its primary endpoint with a highly significant and meaningful increase in progression free survival (PFS). Investors, however, appear to be reacting negatively to the disclosure that a pre-planned interim overall survival (OS) analysis was not statistically significant, despite the fact that these data are not yet mature. We are buyers of SGEN shares on weakness

    today as we believe concerns over the interim OS data are overblown." Less
    May catch a good trade over the next couple days. I made good money on her but sold too soon at 25-28
    last year.

  • oldfolks95610 by oldfolks95610 Sep 25, 2014 1:03 PM Flag

    Good to get a bit of help for the fires. Market could be better, not trading much but trying to hold some stocks.
    Maybe better to put money in tin cans ehh. Go A's and Gigantes still a little hope.
    Old and wet

  • oldfolks95610 by oldfolks95610 Sep 10, 2014 3:49 PM Flag

    Another genetic ipo with good partners but not very far along.

    Rare disease biotech Xenon Pharmaceuticals files for a $52 million IPO


    Xenon Pharmaceuticals, an early-stage biotech with a gene therapy discovery platform for rare diseases, filed on Wednesday with the SEC to raise up to $52 million in an initial public offering. Xenon has a number of collaboration and licensing agreements with large pharmaceuticals including Teva, Genentech and Merck for its preclinical research.

    The company's discovery platform was used to develop uniQure's Glybera treatment for orphan disease lipoprotein lipase deficiency, the first gene therapy approved in the EU. February IPO uniQure (QURE) priced above its range but ended the first day down 14% and now trades down 36% below the IPO price. Xenon is eligible to receive mid single-digit royalties on net sales of Glybera. Teva is in Phase 2 trials for a gene therapy discovered by Xenon that is being developed to treat osteoarthritis. Genentech was cleared to begin a Phase 1 trial for Xenon's pain treatment and Merck is in preclinical development for cardiovascular disease. Xenon also has a variety of preclinical therapies for both orphan diseases (such as Dravet Syndrome) and large-market conditions (including acne).

    Primary shareholders include Medpace (16%), Lipterx (11%), InterWest Partners (9%), Fidelity (7%), Invesco (5%) and CEO Simon Pimstone (4%).

    The Burnaby, Canada-based company, which was founded in 1996 and booked $27 million in collaboration revenue for the 12 months ended June 30, 2014, plans to list on the NASDAQ under the symbol XENE. Xenon Pharmaceuticals initially filed confidentially on August 16, 2013. Jefferies and Wells Fargo Securities are the joint bookrunners on the deal. No pricing terms were disclosed.

  • Reply to

    Sularia and one dollar gas.

    by oldfolks95610 Sep 1, 2014 12:48 AM
    oldfolks95610 oldfolks95610 Sep 2, 2014 3:12 PM Flag

    Sr. Hola, I have to assume this new tech will take time to mature. The amount of venture capital raised seems to add some validation.
    As with anything you can be blindsided by some other new breakthrough like in batteries and Mr. Tesla wanting a huge battery factory and the technology changing so quickly.
    Now we may soon have a good quantity of Hydrogen produced by genetically altered moss.
    What a fun job being a venture capitalist.
    Old and new ventures.

  • oldfolks95610 by oldfolks95610 Sep 1, 2014 12:48 AM Flag

    At Siluria Technologies, we're replacing crude oil with natural gas. Our catalytic process transforms methane—one of the most abundant, inexpensive and widely available hydrocarbons on earth—into transportation fuels and commodity chemicals in an efficient, cost-effective, scalable manner using processes that can be seamlessly integrated into existing industry infrastructure. With our technology, we can reduce oil imports, lower prices for consumers and businesses, increase profits for gas producers, reduce environmental emissions and bring about greater global stability.
    They say they can make gas for a dollar from methane or natural gas etc. They have raised 96 million venture capital already, not public yet. Could have some pins in Natural gas etc. Any ideas on her I wish I had a few bucks in her but maybe other ways to play and just watch for now.

  • oldfolks95610 by oldfolks95610 Aug 29, 2014 3:42 PM Flag

    Spent the day yesterday on the SF. Bay in a 16 ft aluminum boat fishing with the oldest son. A little adventurous for an old guy, it gets rough in a hurry. Only caught a couple of small sharks and a striper and put them back.
    Bio's doing well lately on merger magic I believe. How long before we retrace again in our uncertain world.
    Best all Old

  • Reply to

    Kite day.

    by oldfolks95610 Aug 26, 2014 9:58 AM
    oldfolks95610 oldfolks95610 Aug 26, 2014 11:47 AM Flag

    ISIS going along with KITE in my little basket, trying to retake 40. Nice while it lasts. May add to KITE later on the strength of the trials. Only phase 1 but great results for an early trial. Small sample but is leading KITE to expand trial for another indication and expect earlier approval maybe 2017.
    Old and expanding.

  • oldfolks95610 by oldfolks95610 Aug 26, 2014 9:58 AM Flag

    Nice for KITE up over 15% at the minute. One of mee basket of Genetics.
    Old Kiter

  • oldfolks95610 by oldfolks95610 Aug 24, 2014 11:30 PM Flag

    Oliver (aka Mr. Fluffy) woke me at about 3:30 Sunday mourning with the doors shaking. The kids in San Jose felt quite a bit more. Very lucky that hour kept the injuries down
    Old stirred not shaken.

  • Reply to

    Hola, Old friends...

    by naturalpastime Aug 19, 2014 6:58 PM
    oldfolks95610 oldfolks95610 Aug 22, 2014 1:18 PM Flag

    Maybe a little too much wine with my last post.:) Natural I found Captpussy on a message board with a few people about like our little board here. They are at AGCYF. I haven't posted anything there but I like a couple of there calls.
    Old watcher

  • Reply to

    Hola, Old friends...

    by naturalpastime Aug 19, 2014 6:58 PM
    oldfolks95610 oldfolks95610 Aug 20, 2014 11:48 PM Flag

    Sr. Hola, Mister Natural, Welcome back to the world Mr. Natural. Seems a lot of trouble everywhere now that has creep in during the night and stains everything.
    My family has been spread far and wide by the Irish diaspora many members in all parts of the world. The family surname is Foley and although very distant it has had an effect on all.
    Perhaps time to consider other means to a just end if any can be found.
    I'm still pinning my hopes on a bunch of genetic engineering stocks with promise and trying not to watch too much.
    Babysittnig two Grandkids tonight, life is good

  • oldfolks95610 by oldfolks95610 Aug 14, 2014 10:29 PM Flag

    ARNI gamble for two shots on goal cancer drugs. Early but cheap. Found this from some bio guru and haven't really studied up on her much.
    Old better do more dd.

  • Reply to

    CLDN to heal a barely beating heart.

    by oldfolks95610 Aug 11, 2014 10:44 PM
    oldfolks95610 oldfolks95610 Aug 12, 2014 10:30 PM Flag

    Secondary priced at 9.50 and down 6 percent plus. I'm going to grab a bit when the smoke clears a bit more.
    I have a little basket of almost all now. SGMO, KITE, BLUE,QURE, ISIS, and now CLDN. I believe Juno may do an ipo also. I'm sticking them away for awhile.
    Old with a tear for Robin

  • Another genetics company starting trial in UK. I may get in as soon as secondary is priced.
    I own a small piece of most of the genetic engineered co's. Now let's keep Janet quiet.
    Old going slow

  • oldfolks95610 by oldfolks95610 Aug 3, 2014 5:48 PM Flag

    Best of luck surviving the default and the troubles that follow.

  • oldfolks95610 by oldfolks95610 Jul 15, 2014 12:42 PM Flag

    - The Federal Reserve on Tuesday voiced concern about stretched valuations in certain corners of the U.S. equity markets, including the small cap, biotechnology and social media sectors.

    The unusual comments from the Fed's monetary policy report - the first time in 14 years that the Fed has commented specifically on valuation of a particular equity sector - that accompanied Fed Chair Janet Yellen's semi-annual testimony to Congress, hit stocks in riskier sectors of the market.

    Yellen said in remarks to the Senate Banking Committee that valuations across equity markets remain generally in line with long-term averages, but the Fed's report said the forward price-to-earnings multiples for smaller companies and those in the biotechnology and social media sectors appear "high relative to historical norms."
    No need to speak about Bio stocks until you talk to me.
    Old being spanked by Jan

  • Reply to

    Must be playing soccer (football)

    by oldfolks95610 Jul 7, 2014 3:43 PM
    oldfolks95610 oldfolks95610 Jul 14, 2014 8:38 PM Flag

    Sr Hola. the Germans are a machine butt your home team put up a great effort.
    110degrees F here today. Not playing for a few days. I found an old poster from WFR days.
    CaptionPussy and a few people have a board about like ours. I
    didn't say much there, I'm using them for some ideas. AGCYF I believe is the symbol,
    Old just win baby

  • I must be playing soccer, getting kicked around all day today and never scoring.
    Old and insulted and injured.

  • oldfolks95610 by oldfolks95610 Jul 4, 2014 12:10 AM Flag

    Doing well for me up 75 % since Sr. Hola mentioned it. How about another 40%.. starting to get some market buzz

  • Wow the best song in the history of r&b-no really
    I think that is what those people are drinking over at USU-a bankrupt company that received a small contract from the Government for 2.5 million. This stock went from about 3 to a little over 12 in short time. Can you short a bk stock? Maybe time to put the others on a close watch.

    STEM taking off on a upgrade, put in a limit order at about 2.15 and don't think I'll get filled, maybe next week.
    Old dancing with Pointer Sisters.

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