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Titan Pharmaceuticals Inc. Message Board

papaalien2000 8 posts  |  Last Activity: May 21, 2016 9:50 AM Member since: Jun 16, 2003
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  • Reply to


    by kellermath May 20, 2016 5:47 PM
    papaalien2000 papaalien2000 May 21, 2016 9:50 AM Flag

    share your feelings, have been in ttnp for quite some years, suffered through iloperidone and other candidates that never materialized, but now I am hoping for a well deserved and long awaited for reward.

    btw, what happened to my long time friend windsurfar, he more than a decade ago pointed out that implants would some day be the most valuable titan product.

  • papaalien2000 by papaalien2000 May 6, 2016 5:09 AM Flag

    AbbVie ($ABBV) has expanded its cystic fibrosis deal with Galapagos ($GLPG), positioning the Belgian biotech to pocket $250 million (#$%$218 million) more than under the original agreement if it hits all of its milestones. The dialed-up deal follows a shift in focus from double to triple combinations of cystic fibrosis drugs, an evolution that has increased the early-phase workload Galapagos is shouldering.

    Galapagos is aiming to start testing its triple combination in humans next year.

  • papaalien2000 by papaalien2000 Apr 4, 2016 12:13 PM Flag

    Orkambi: Investors can't seem to reach a consensus trajectory for the drug's early launch, except that it's been slower than everyone first believed it would be.
    The sell side and the buy side already have cut Orkambi sales estimates this year. The worry now is that another downward revision might be necessary if Vertex's first-quarter earnings coming later this month come up short.

  • Reply to

    Leiden should be fired

    by gladpick Mar 29, 2016 2:04 PM
    papaalien2000 papaalien2000 Mar 31, 2016 7:04 AM Flag

    q, VRTX pipeline certainly would warrant a higher share price, but fact is, VRTX has lost much more value than its peers. So there must be specific reasons. In my opinion it is the lack of forecast for Orkambi sales. Management indicates that in real life application Orkambi might not be as good as expected. VRTX needs to give reliable forecasts for Orkambi, if they do not provide that guidance the sp will continue to decline.

  • Reply to

    God, what is going on?

    by whtthefk Mar 23, 2016 12:20 PM
    papaalien2000 papaalien2000 Mar 24, 2016 8:55 AM Flag

    VRTX refusal to issue forecasts for sales of Orkambi has contributed significantly to investors uncertainty. Highlighting potential drop-out rates for patients on Orkambi has confused investors, too. Next CC with quarterly sales of Orkambi in April may bring some clarity. Until then I expect more volatility in sp.

  • Reply to

    Barclays Healthcare Conference

    by papaalien2000 Mar 16, 2016 3:45 AM
    papaalien2000 papaalien2000 Mar 17, 2016 7:51 AM Flag

    is it really a worthwhile effort to highlight potential problems of the lead product? VRTX ought to focus on the big picture: sales potential iva and orkambi, VX-661, second gen. compounds, non cf pipeline etc.
    Right now VRTX keeps providing the impression that it is facing problems with orkambi. The sp reacts accordingly.

  • papaalien2000 by papaalien2000 Mar 16, 2016 3:45 AM Flag

    why is VRTX participating in such conferences when they have nothing to talk about, but potential drop-out rates for orcambi? Such discussions will not enhance investors trust in the company.

  • Reply to

    How much is thing worth in a buyout?

    by garroty Mar 9, 2016 1:22 PM
    papaalien2000 papaalien2000 Mar 10, 2016 11:46 AM Flag

    I agree that a take-over is highly unlikely. Guess, all of us don't understand why VRTX has lost one-third of its value in the last few months. There have been no negative setbacks that might explain the drastic loss in value.

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