Irish , i truly have appreciated all your kind posts.. and to be honest they where a relief to read that there was hope ... please don't go ..Many of us really appreciate your updates... hope John is doing wonderfully..
Baked Foods Distributor will Add 25 Natural Gas Vehicles to its Delivery Fleet that Services McDonalds Corporation
MIAMI--(BUSINESS WIRE)--Ryder System, Inc. (NYSE: R), a leader in commercial fleet management and supply chain solutions, announced today that Northeast Foods has signed a full-service lease agreement for 25 compressed natural gas (CNG) tractors. Northeast Foods, a baking company and food distributor based in Baltimore, Md., will use the trucks to support its distribution and delivery operations that exclusively service McDonalds Corporation. Northeast Foods has been a key supplier to the McDonald's fast food chain since 1965 and is now the largest supplier of buns in the United States. This will be Ryders first natural gas lease customer in Maryland. Ryder will provide maintenance for the 25 CNG vehicles from Ryders Baltimore service facility, which is being upgraded for compliance with natural gas standards.
When companies like Northeast Foods choose Ryder to manage their fleets, they can focus on driving what matters to them managing their core business and servicing their customers.
With several years of experience operating and maintaining natural gas vehicles, we are in a unique position to help businesses leverage our expertise by making advanced fuel vehicles available through our lease and rental arrangements, said Ryder President of Global Fleet Management Solutions, Dennis Cooke. When companies like Northeast Foods choose Ryder to manage their fleets, they can focus on driving what matters to them managing their core business and servicing their customers.
Northeast Foods is a family-owned business that has been in operation since 1943. The large baked goods distributor is owned and operated by four brothers; Steve, Bill, John Jr., and Chuck Paterakis, who took over the company from their father, John Paterakis Sr. Northeast Foods distributes ba Less
interesting snippet .. " Specifically, we found that two unrelated
pharmacological inhibitors of p21, sorafenib and UC2288, could
function synergistically with imetelstat. Notably, in both cases,
growth inhibition could be counteracted by ectopic expression of
p21, indicating that sorafenib and UC2288 functioned by inhibiting
p21 and not through an off-target effect. The induction of apo-
ptosis by simultaneous inhibition of p21 and telomerase may
greatly reduce the likelihood that resistance to telomerase
inhibitors will develop through additional secondary genetic
alterations or activation of ALT pathways. Finally, we show that
simultaneous inhibition of telomerase and p21 also suppresses
growth of tumors containing mutant p53 following pharmaco-
logical restoration of p53 activity.
Overall, we anticipate that simultaneous inhibition of telo-
merase and p21 can potentially overcome the current limitation
of single-agent telomerase therapeutics and provide an effective
method to treat a large number of cancers that rely on telo-
merase activity for survival, including the p53 mutant cancers.
The part that Jak inhibitors are being tested with other agents ? you think Imet?
i have written them as well.. i usually get a reply ..but nothing from my email yesterday.. .. keep up the fight.
they don't give us any updates...... all up to us.. its ridiculous... only good thing is we have a chance to accumulate at these levels..
good luck .. i have seen the mm mess with options alot and it scares me to be honest... we need the hold to be lifted.. asap
Good question...... i have been trying to search and search but it seems to be top secret............. i seem to remember they had .. some agreement for vaccine testing in bio terror...but obvioulsy not a word since.... anyway .. i just hope some company has something that works ..so we can get on with our lives and not worry about this horrible disease..