According to Yahoo stats more than 110% is owned by institutions + insiders, while ~20% is being borrowed by shorts: effectively twice owned by institutions. Even if only 5% is owned by indies, any real competition to cover shares will quickly result in an intense squeeze... on paper anyway.
Don't know if the everydaybiochemistry piece has made the rounds
Google "Belviq may be repurposed for cocaine addiction" and it'll come right up.
Sorry to see so many lose sight here.
It's not just about today's SP or current failures in marketing a bio that results in incremental improvements.