Get this drug approved and available in the marketplace. Seroquel and clozapine have not improved my father's Parkinson's dementia. This drug is so necessary for Parkinson's. I cannot speak for other maladies.
Don't you get the feeling that they are one in the same? One day long, the next short. I agree with you, except what is a jojo? Did you mean yoyo?
My father was until recently on quetiapine (Seroquel generic). His new psychiatrist has put him on clozapine. I don't know what clozapine costs, but quetiapine is inexpensive (at least relative to my middle class standards). Quetiapine did not work well (possibly the dosage was not high enough), so I'm expecting great things from Pima. I can't wait.
I'd prompt the Doctor at the first signs of dementia (assuming covered by insurance/medicare). By the way, what is a monthly dosage of this going to cost?
Its difficult to say when the Parkinson's dementia sets in. My father was 1st diagnosed in 1996. He's been acting pretty squirrely since 2005. Now in 2013, he - to use a medical term - is nuts. Caregivers will definitely notice changes after 10 years of the disease. I don't know how much more time my father has, but if Pima was available I would pressure the Parkinson's specialist to prescribe it. This thing will have a big market (assuming it is approved).
I don't know too much about Pima, but I do know about Parkinson's dementia (since my father is deep into it). Advanced Parkinson's patients can be quite crazy and it takes a big toll on the family and caregivers. There is a need for a drug that works (of course, the patient has to actually take the thing). My father takes Seroquel and clonopin for his dementia. I'd love for all advanced Parkinson's patients with dementia be given the opportunity to take Pima. As for Michael J. Fox, all Parkinson's is different. He may not have dementia (or get it). His did not have deep brain stimulation (like a pacemaker for the brain), he had something different. Maybe his surgical decisions were made based on the technology at the time. Regardless, he would be a good candidate.
I just returned from the hospital tonight. My father was sent via ambulance from a rehab facility because he was combative and the facility didn't wish to deal with it.. He has had parkinson's disease since 1996. He tolerated it quite well till around 2005 or so. Then things got very strange. For the last couple years, life has been very difficult. My mother could not take it anymore and moved out a couple months ago. He stayed in the house for a while longer with family help until he broke his hip. He has been in and out of hospitals and rehab facilities ever since. Parkinson's changed my father. I don't think my father will every see a dosage of pima, but others will. If this drug works, it will be huge.