FUD is kinda like the Teabags masters focusing them on Obama's birth certificate while Carlyle and the kochsuckkers rob them blind.
She let the cat out of the bag. End of story. How does she know they are living longer??? She tries to cover up her mistake by saying we are still blind. But the DMC is NOT blind and they have an interim look at 148. I have already told you that IMO the interim look has already occurred and is NOT good (more or less confirmed by Liau's slip of the tongue "bad for our study"). My guess is that they closed enroll,int short 0f 348, broke the blind and are now torturing the data for sub groups. There is ZERO chance that they haven't reached 148 events by now.
Most don't think it is a scam. They just think DC-Vax isn't going to succeed. Basing your decision on two board members is a very poor way to analyze your speculation. Looking for love in all the wrong places.
You might learn a bit about the science and clinical trials.. Looking at the history of this trial would also be helpful
"Isn't the ideal cure one that once given, you feel better as it kills the cancer?"
Since you asked the answer is no. Th ideal cure is to click your heels together and say "begone cancer you have no power here". Unfortunately those of us living in the real world realize that the same process that provides the therapeutic benefit also should cause toxicity. If you are not seeing AE's the product is probably NOT working.
NWBO fools keep living in fairyland. Although the jury is still out, it is not looking good for DC-Vax.
Good article. You didn't understand it but it just confirmed what I already knew. Toxicity = efficacy. Lesson learnt. The MOA that makes it effective also makes it toxic, that's what donks like you don't understand..
If it's not about DC-Vax why post?
If it's about CAR-T's I already know there are AE's associated with them as I done told you before. The AE's are evidence of their efficacy. That's probably the part that has you confused. NO AE's probably no efficacy. See e.g. DC-Vax.
PS - NOTHING necessitates any of your gibberish.
That's because CAR-T works. Efficacy comes with toxicity. No toxicity-no efficacy.
Enrollment is not gonna be 348. Take it to the bank. PS They have already had the interim look and are torturing the data for subgroups. Take that to the bank as well.
Cherry picking and failure to screen for subtypes are two different issues. They did , in fact, cherry pick. This isn't uncommon in p1 trials. In fact Liau refers to this aspect of p1 trials in her video. Researcher call it "selection bias" but us common folk call it cherry picking.
Go to your nearest community college. Enroll in remedial grammar course and logic 101. It will be money well spent.
What Phase 2? Two very tiny p1's total about 33 patients. Patient were cherry picked much younger than avg. Well known that younger patients do dramatically better., Both trials used different protocols than this one. Not al patients were GBM--- All of that is That is EVIDENCE but doestn't the meme. The trouble is that schools uno longer teach critical thinking. That's why we have REPUBLICANS.
You must be a Republican. Did you like Palin's incoherent babble?
Several of the posters have posted FACTS, you just choose to ignore them.
1) The first interim look did occur over 2 years ago-Fact.
2) The trial was changed very shortly after the interim look- FACT
3)The trial size was increased to "show increased statistical power" - FACT (Do you know why?. You should)
4) New enrollment was halted before 348 patents were enrolled.
5) The halt was initiated over 5 months ago with no news since then- FACT
Draw any conclusion you wish (or none at all) from those FACTS
You're like the Polacjk who fell from a 40 story building and after he passed each floor said "I'm OK so far."
BTW you could ask D2 if hew's ever seen anything like this before. ONCY pans trial was about 15 months late in preventing data-- Must be good news right? Everyone is living longer. Psych!!!! isasterrous results . Company refused to give OS. Take it from one who know --Longer is NOT better in clinical trials. My guess (based on formidable intuition) is that NWBO has already broken the blind and is torturing the data looking for some subgroup that is doing well, as we speak.-- hence the 5 months and counting. I also think they will wait as long as they can before relasiing results.The data is still trickling in and they are praying for a miracle. But miracles rarely happen in statistics. FYI there is NO timetable for reporting 8-k "other" material events
Jut what it said. An esteems and 348. With the fad shutdown you can throw the 348 out the window.
No longer recruiting is as a result of the FDA imposed halt. It doesn't mean it's fully enrolled-- at least according tot eh original estimate of 346 or whatever it was. Full enrollment is an estimate . NWBO may have closed recruitment permanently which by definition makes it "fully enrolled" but it ain t wit the original estimated number. That's a fact.
Hers's a defense clown-- You can't read
No longer recruiting refers to the "temporary" halt. It design not mean the trial is fully enrolled
You moron. It does not mean they are fully enrolled. It means recruitment is HALTED you donkey. Also the initial poster is wrong. You don't need full enrollment to reach a median. He is correct that it may take longer.