You nailed it Whipper, and I am glad you did. He likely will not retort.
I will add one well known quote from R. Reagan...
--"The trouble with our Liberal friends is not that they're ignorant; it's just that they know so much that isn't so."
Christie is so bad that NJ made him governor twice. He is so bad, that a Democrat state like NJ could not field a candidate to win.
If Christie is as bad as you say, just how bad are the Democrats in in NJ?
That's because Cy is all concerned his queen is losing the election. He is off the charts attacking the only black man running for office this cycle.
Just look at who is authoring most of the new post that have nothing to do with Celldex. Yes, it is Cy.
Cy, if you wish to make charge against me, back it up.
---"YOU constantly make up horrible things about people and groups of people you don't like"
Otherwise, watch your mouth. And yes, you should be careful for the reason I stated, and simply because you are coming off sounding like a little leftist punk, afraid your little Clinton queen won't be anointed, and willing to say and do anything to protect the queen. And if that means destroying the black man who is conservative, you are certainly willing to cast the first, second, and third stone.
Cy, have you ever heard of confession and redemption? He was 14, and fatherless. Yes, he was lucky as well, and he has stated such.
And he knows he has "only his self to blame", a lesson from his mother. Which is why he owned it and changed it.
Cy, careful with what you continue to write, God is always watching.
Cy, Hillary clinton lies over and over again, and you give her a pass, Ben Carson does not lie and you suggest he is like Brian Williams. Why would you do that? Actually, we know why you would do that.
mike, "NOT QUALIFIED FOR A HIGH STRESS JOB"
Have you lost your senses? The man is a world class pediatric neurosurgeon, and led a team to successfully separate conjoin twins at the head. Do you have any idea how stressful his chosen career has been? By all accounts, he excelled at this HIGH STRESS career.
So #$%$, Respectfully of-course
"The Company will present an update on overall survival and long-term survival in a podium presentation at the 20th Annual Scientific Meeting of the Society for Neuro-Oncology (SNO) on Friday, November 20th at 1:30 PM CT/2:30 PM ET."
cyntiques, thanks for offering your qualified perspective. Your position as a person in a similar circumstance and time certainly helps to shed additional light on Carson's possible circumstance. Thanks for speaking up.
"The immune stimulating and Treg depleting effects of varlilumab were also observed in Celldex's Phase 1, single-agent ((((clinical trial of varlilumab in patients)))) with refractory, advanced cancers. Specifically, varlilumab administration was associated with a rapid and transient induction of pro-inflammatory cytokines, activation of T cells as assessed by increased HLA-DR expression and a significant decrease in circulating Tregs. The study also demonstrated promising clinical activity. Two patients experienced durable objective responses including a complete response in Hodgkin lymphoma (18.9+ months) and a partial response in renal cell carcinoma (13.6+ months). Thirteen patients experienced stable disease (3-36.2+ months). Varlilumab was very well tolerated and demonstrated minimal toxicity, even in elderly patients. There was no indication of immune-mediated adverse events often seen with other immunotherapies. Varlilumab is currently being studied in multiple ongoing Phase 1/2 clinical trials with several anti-tumor agents, including nivolumab (Opdivo®), ipilimumab (Yervoy®) and sunitinib (Sutent®) in advanced-stage cancers. Efforts are underway for additional Phase 2 studies with varlilumab, including a combination with atezolizumab (Roche's anti-PDL1 antibody), and the Company will provide updates on these studies as they are initiated."
Actually communist cujo,
"Our collection of preclinical and clinical results to date support Celldex's broad clinical development program across tumor types and in combinations with other anti-tumor agents.""
'"Our data show that CD27 modulation through varlilumab results in immune activation and suppression of Treg activity, either of which can be independently responsible for a therapeutic effect, depending on the cancer model," said Tibor Keler, Ph.D., Executive Vice President and Chief Scientific Officer of Celldex Therapeutics. "Because individual human cancers are also likely to have different sensitivities to these anti-tumor activities, varlilumab's ability to act through both mechanisms provides the broadest potential for therapeutic benefit. Our collection of preclinical and clinical results to date support Celldex's broad clinical development program across tumor types and in combinations with other anti-tumor agents."
To better understand each mechanism separately, scientists engineered varlilumab to possess either strong co-stimulatory activity (varli-mG1) or strong Treg suppression activity (varli-mG2a) and analyzed their efficacy in several preclinical tumor models. The data indicated that potent co-stimulation activity was required for therapeutic activity in a BCL1 lymphoma model, whereas control of Tregs was required for activity in several other models, such as E.G7 thymoma, CT26 colorectal and colon 26. Importantly, varlilumab has a combination of immune co-stimulation and Treg depleting activity and demonstrated potent anti-tumor activity in all the models."
Thats because they had a 92% tax rate with 78% deductions. Why else would the tax code be so vast?
Frank, that guy is just mad we have him on iggie. I personally just did not want to deal with his lies. What ever he said, thanks for speaking up. I'm sure this post will set him off again, but then I will not have to read it.
Frank, this is just another American Leftwing Lynching of a prominent black conservative. Disgusting to a degree which the left will have to pay a price for their uniquely specialized black conservative attack.
And if the Republican establishment had anything to do with this witch hunt and lynching, they must pay a price as well.
Conservatives are watching...
halftrack, I would expect a comment like that from a guy that hears of a Muslim American lopping of a coworkers head, and you call it workplace violence only.
Because beheadings at work happen all the time in America. Oh wait, they never happen, except the one time, due to workplace violence. You know, much like Nidal Malik Hasan in Fort Hood. Workplace violence.
We sure are seeing a lot of workplace violence in the middle east, that seems to be spreading around the world.