Frank, I listen to most of them. And as leftist as Bloomberg is, their interviews with top business leaders, disrupters of industry, and general content is by far the best. IMO
Almost a "yellow brick road", grey. We may have to throw some water on that wicked witch Dorris, the evil witch of the south moving SP.
You know who else expects a positive result? Celldex management. I don't think they could legally telegraph their thoughts on the matter any more than they have been doing. They have been very clear about ramping up for commercialization, and that is backed up by a whole-lotta hiring going on around here.
This is going to be such fun...
Dorris, Dorris, Dorris, when the final ReAct data is known, and if that data maintains it's previous "statistical significance", (and according to Celldex, it could get even better) the SP pressure will be significantly to the upside as Celldex and company marches said ReAct data over to the FDA for potential early approval. You know the same ReAct data that earned Celldex's Rintega a shinny new moniker called "breakthrough therapy designation".
"Everytime you have a disagreement with me you call me a leftist. "
Cy, If the left shoe fits, wear it. Though I do hear you questioning your previously held leftist assumptions, on occasion, recently.
I get the feeling your son is a thoughtful one, and the two of you may be engaging in some healthy bantering on occasion.
Kay, for a moment, put down your politics, and your emotion. The facts are the facts, TM viciously attacked Zimmerman, and attempted to sustain such injury on the neighborhood watchman as to have the watchman pleading for help while he lay on his back, having his face pounded, and the back of his head repeatedly slammed against the sidewalk in an effort to cause at least significant injury to the victims head.
How long are you personally going to sustain such an attack before pulling your lawful weapon in hopes of defending yourself, by firing one shot at your attacker, who has no regard for your continued existence?
For a moment, think, put yourself or your family member in that moment. Then respond. But don't say such an event could never happen to you you or your family. It happens.
Do you, and others know better than the jury charged with deciding the truth, a jury instructed to apply the law when coming to their decision?
Well, there is the OJ Simpson case. I'll give you that much.
"Beating up women and shooting a black kid"
Do you read your post, Cy? Let's see how you would do mentally when the leftist press, the US president, and most of the black community treat you like a murderer, even after your complete acquittal of all charges.
A double edged sword, another Glioblastoma treatment prospect fails, but leaves Celldex investors in good stead with Rintega.
If by "took arms against the oppressors", you mean, killed a violent attacker in self-defense, and in fear of his life..., then yes, he may be your kind of hero.
Totally? Totally unproven? Not regarding Rintega & Varli my friend. Not approved, but certainly not totally or completely unproven.
Hey Shorts, are you paying attention to this??? You guys are nuts.
"Pt. 2, AACR'15: Varli + PDL1 inhibitor combination in solid and hematologic cancers"
Thanks for the post long_vrts2, I just like reading that post, and the post below that one that speaks of Celldex's ownership of IP on antibody based CD27 agonists, is a good bolt on to anyones thoughts of shorting Celldex. These guys are have lost their minds shorting Celldex like this.
"I know of one academic lab that is working on CD27 antibody agonist, but CLDX owns the IP on antibody based CD27 agonists, so nobody can advance a CD27 program without CLDX's approval. And I don't see CLDX approving anything in this area because of the substantial potential of CDX-1127."
"Pilot Study of SBRT and CDX-1127 in Prostate Cancer (Prostate-04)
Estimated Enrollment: 21
Study Start Date: November 2014
Estimated Primary Completion Date: March 2017 (Final data collection date for primary outcome measure)
ClinicalTrials.gov processed this record on May 07, 2015"
So what is that, 29 months?
Now this is a small study, but may give you some kind timeline as to completing a similar trial of 1127. I suspect a more complex or larger combo trial would take more time to complete, but combo trials with previously approved drugs could fill faster due to increased interest in said trials, and may shorten the time to completion by a few months as they may meet enrollment faster than most.
I think 2017 will be a pivotal year for Varli combo data. But I think the general trend of how Varli combos are doing will be generally known before 2017. Just too many trials taking place for early speculators to get at least early anecdotal info. There is reason for real optimism regarding these combo trials, and they will be eagerly watched by all. IMHO.
In your calculations, take a look at how the Rays are decimated by injury. It's hard to believe such a young team could have so many injuries so early.