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Cleantech Solutions International, Inc. Message Board

rchites 1072 posts  |  Last Activity: 1 hour 14 minutes ago Member since: Apr 12, 2004
  • Reply to

    Is Caliber going to get a contract?

    by tddaytrade Dec 3, 2014 11:11 AM
    rchites rchites Dec 3, 2014 12:51 PM Flag

    Bayer and NOMAD is ICON..... Bayer is nothing in the field with out ICON. WILL or national security depend on Germany-Bayer? Prove in the press or any of the DOD NIH statements say they feel comfortable with KBP???? THEY all say the world needs more supplies/suppliers and are looking elsewhere. DDaaa,... IN the testimony AMGEN is also getting help...... The government is covering their $%^&* on this with many suppliers and drugs.... And with all your wisdom , Caliber the largest maker will not be used as it was designed for this purpose.

  • Reply to

    Is Caliber going to get a contract?

    by tddaytrade Dec 3, 2014 11:11 AM
    rchites rchites Dec 3, 2014 12:46 PM Flag

    Robert stated his patents are good in the USA and ICON can not ramp plant ZMAPP in the USA over current production levels with out IBIO plant technology -period. I have not seen any thing different from ICON or Kentucky other then 20 doses a month. IF schinzo is so informative and right make him prove it..... HE CANT ! period. He is like a little kid saying my $%^&* is bigger... Its time for him to prove his BS.

  • Reply to

    Is Caliber going to get a contract?

    by tddaytrade Dec 3, 2014 11:11 AM
    rchites rchites Dec 3, 2014 12:38 PM Flag

    YA right...... That's why BARDA is producing animal ZMAPP also... because KBP can do it. .. GET a clue and brain. BECAUSE they can ramp... I don't believe you over the CEO of IBIO. He knows ICON. BAYER is a Germon firm and quit the plant program many years ago. All the experts agreed and it was in the press early that KBP could not ramp. That is why BARDA went out to the other manufacturers because KBP has it under control. Caliber is the biggest and will most likely be used KBP is very small. I believe the White house when they said they would support the ramp and optimization... That leaves Kentucky out or it would have been done with the same exact 3 doses. MY GUESS is you don't know what you are doing and cant read about KENTUCKY and ICON license and patents. BARDA has been in talks with Caliber.... cant you read. NOMAD products that were made with ICON patented technology in EUROPE... The IBIO CEO maintains the IBIO hold precedence over ICON patents.....

  • Reply to

    who is this schinzo123 guy?

    by starteam003 Dec 3, 2014 11:54 AM
    rchites rchites Dec 3, 2014 12:03 PM Flag

    He is most likely a day trader that will never tell you his agenda. He could be working for Aspire or a hedge fund trying to get cheaper shares. He could be a complete whack job asking the same questions displaying the same negativity every day. Some guys just like being stupid and getting beat up.

  • Reply to

    Is Caliber going to get a contract?

    by tddaytrade Dec 3, 2014 11:11 AM
    rchites rchites Dec 3, 2014 11:28 AM Flag

    your an FOOL. The White house fact sheet just said they will support plant technologies ZMAPP. ITS CLEAR they want the new contract to ramp and be optimized. BARTA called on three manufacturers...... ONE ) Kentucky cant ramp. 2) Medicago is tied up with influenza vaccines 3) GSK/TEXAS? Caliber..... KENTUCKY could license. Other Ebola plays could license to ramp a lot faster. The field will get attention and the door is open. YOUR a bashing fool. The amount of companies involved are mostly Vaccines .... DAaaaa. This is a cure and the fastest one available. The rest are mammal based........ 6.2 billion is a lot of money. The testimony of Robinson and the White house fact sheets say you have no point.

  • Reply to

    what happen to IBIO?

    by starteam003 Dec 3, 2014 10:07 AM
    rchites rchites Dec 3, 2014 10:22 AM Flag

    every thing looked up..... Maybe it has some thing to do with the offering and the S-3. Nothings changed as the offering is registered and effective. Its their for a major development or contract. could be used against hostile take over.

  • Reply to

    richites..

    by starteam003 Dec 3, 2014 8:59 AM
    rchites rchites Dec 3, 2014 9:36 AM Flag

    when was the last chance you got an 80% chance of a double and triple in less then a year? You have a 10% chance of a 10% move down on the flip side. ICON could get the optimizing technology and produce over seas some where. I DONT think BARDA was designed for that as the testimony said Domestic. Plantform and our partner FCMB could use IBIO technology with out a license and license later as production develops. NOVICI and Caliber could win big contracts. IBIO could be the big winner with no direct contracts to the rest of the EBOLA field and wind up with a huge royalty wind fall. ZMAPP is being studied by many researchers . They may break it down to a couple serums and doses. It may be tested against many diseases once it is field tested.

  • Reply to

    richites..

    by starteam003 Dec 3, 2014 8:59 AM
    rchites rchites Dec 3, 2014 9:24 AM Flag

    Now, I am 80% sure the technology will be used. YOU may never hear IBIO from BARDA but GSK and Texas A&M., NOVICI and Caliber could get press Roberts words still ring true...... IBIO license and technology will be used in the US if they produce (over ) currant levels. ICON

  • Reply to

    max and richites..

    by starteam003 Dec 3, 2014 7:21 AM
    rchites rchites Dec 3, 2014 8:32 AM Flag

    InfrastructureGE Healthcare has KUBIO plant design that makes it affordable for most countries to have their own ability to make medicine through IBIO's platform. KUBioTM, an innovative off-the-shelf, modular factory designed to save manufacturers of biopharmaceuticals both time and money. KUBio’s pre-made modules Fraunhofer USA Center for Molecular Biotechnology , GATES, DOD, DARPA, Kanematsu Chemicals Corporation- Japan ,Oswaldo Cruz Foundation-brazil, China building 3 IBIO plants all with out contracts the basher would like you to think.......its about many successes and diseases. ...... , ITS disruptive- iBioLaunch platform has been proven - Huge pipeline. Once the door is open with approval of a plant based product..... (Malaria, YELOW FEVER, Hookworm, HPV, H1n1, H5n1, H7n9, Fibrosis on and on).
    • Monoclonal antibodies
    • Interferons & cytokines
    • Enzymes for replacement therapy
    • Plasma-derived proteins
    • Growth factors
    • Protease inhibitors
    • Clotting factors
    • Vaccines The company’s product candidates comprise IBIO-CFB03, a product for treatment of idiopathic pulmonary fibrosis; C1 Esterase Inhibitor, a plasma-derived protein; Alpha-Galactosidase, an enzyme replacement protein; and Palivizumab, a monoclonal antibody for the therapeutic protein market. Its vaccine products include H1N1 Influenza and H5N1 Influenza products that have completed Phase I human clinical trials, as well as yellow fever vaccine; malaria and hookworm parasitic pathogen vaccines; and human papillomavirus therapeutic vaccine. The company’s product candidates also comprise Anthrax/Plague bacterial disease vaccine; and Anthrax, a monoclonal antibody for the biodefense market.

  • Reply to

    max and richites..

    by starteam003 Dec 3, 2014 7:21 AM
    rchites rchites Dec 3, 2014 8:22 AM Flag

    on the 3rd generation plant based level.... BARDA is going to have AMGEN make plant based methods with the help of GENENTECK and Regeneron. It came out earlier that ZMAPP antibodies did not grow well using the animal traditional ways. The traditional ovary method has many different manufacturers and a vast network but they have hurdles to get over first. This is why I feel Robinson in his last director testimony called for Genentech and Regenerons help. A week later this White House fact sheet was very good for plantibodies developments. **** Right now, we are in the early innings of the greatest profit opportunities of the 21st century. A biotech boom is about to hit epic proportions thanks to Ebola. Ibios’ foot is in the door and its pipeline will flow through the door. iBio said the "superior homogeneity of antibody glysolylation," or the addition of sugars to proteins, in plants could have significant efficacy advantages compared to similar antibodies produced in Chinese hamster ovary (CHO) cells. *** Lower-clost, plant-based drug production will not be replacing current methods using mammalian cells in the near future but some early adopters are betting that it's only a matter of time. Washington journal – John Kerry, we know the science and what is needed. All hands on deck. Licensing could take off = If they can strike deals with MAPP and ICON. The Icon Genetics unit of Bayer AG is currently conducting a Phase 1 clinical trial of individualized cancer therapy based on their transient expression technology for producing proteins in plants. PIPELINE FOR MAPP Clostridium, HIV/HSV, Junin, Marburg, a repertory Virus, Risin, Staphylococcal enterotoxin, encephalitis. PIPELINE for the whole industry .......... Ibio pipeline is about to blast off with approvals.

  • Reply to

    max and richites..

    by starteam003 Dec 3, 2014 7:21 AM
    rchites rchites Dec 3, 2014 7:56 AM Flag

    Even if iBio fails to become part of the Ebola response the ZMAPP production ramp is a huge catalyst for PMPs. Success with plant ZMAPP would be a pivotal event for the PMP movement. IBIO has the major foot print in the industry and should do well. *****Barriers broke- To date there have been no FDA approved plant-made pharmaceuticals (PMPs). This has made a barrier to entry for iBio and any other companies focused on PMP production. ZMAPP is a game changer… IBIO has their own pipeline. This could be worth hundreds of millions with FDA approved methods.... The whole industry could ramp.... IBIO platform will be looked at by other companies. They and licensed partners could be the hottest thing in biotechnology. ALL the vaccine makers should be taking note. IBIO could be a partner to many of these EBOLA plays. They could be the biggest winner in the industry and the one link pin they all use for future out breaks. EBOLA has mutated 300 times according to researchers.... Will we be prepared??? I hope so and I hope it don't take a year and a half to get ready. SERUMS in two years ((( give me a break)))) IBIO IBIO IBIO !

  • Reply to

    rchites..

    by starteam003 Dec 2, 2014 10:13 PM
    rchites rchites Dec 3, 2014 7:37 AM Flag

    IT is official they are supporting the making plant based ZMAPP. I would even guess NOVICCI is involved with ZMAPP already and gave the thumbs up. They have ran live fire testing of IBIO technology. Before the White house gave us the press about plant ZMAPP they did their research and went over the BARDA proposals. I would grab enough shares in pre market as this is another green light. We have had bashers study the industry as well as us longs. Roberts statements still stand true. ITS worth adding a few more. I AM COUNTING my shares............. The door for plantibodies just OPENED and the major players will get press in a couple weeks to a month. BE PREPARED with enough powder.

  • Reply to

    rchites..

    by starteam003 Dec 2, 2014 10:13 PM
    rchites rchites Dec 3, 2014 7:27 AM Flag

    Please inform me of others that have 3rd generation plant solutions to replace Animal Antibodies with plantibodies and the fast, cheaper, scalability and optimizing science IBIO does...... The bashers here are short on words with facts.... READ the press---- . KENTUCKY DONT . Now, when you do the home work you will find that other technologies take much longer and can not do it in terms of weeks...Show me a cure that states they can be ready in a couple months??? IBIO has did it before ((( LIVE FIRE TESTING)) .The government sponcered the test.... ... Most say they can ramp in something like a year. Very unfortunate for every body. Then read about the scalability , ramping put out by the white house press release.............. 1st generation, transgenic –plants are genetically engineered – slow process… . 2nd Generation- is based on transient virus-delivery of genes into non-transgenic plants,( non-engineered plant) . You target the whole plant and fundamentally alter a host cell’s DNA changing the plant …… 3rd Generation- there is no need to isolate and expand rare, high-producing cell clones to production level. A gene of interest can be cloned and inserted into the iBioLaunch vectors and be ready for production at scale within a month’s time.

  • Reply to

    scale up to produce millions

    by rchites Dec 2, 2014 9:12 PM
    rchites rchites Dec 2, 2014 9:14 PM Flag

    Who do you think they will go to scale and optimize ???? any body know where they can get 3rd generation mass production?

  • Reply to

    scale up to produce millions

    by rchites Dec 2, 2014 9:12 PM
    rchites rchites Dec 2, 2014 9:13 PM Flag

    HELLO FDA approval of plant antibodies ------ we will hit the moon. Its in the cards

  • I have died and went to heaven. BARDA with FDA assistance is supporting the rapid scale-up and optimization of vaccine manufacturing for these vaccine candidates to ensure that the capacity exists to produce millions of vaccine doses in a timeyl way if mass vaccination campaigns are able to occur in 2015 in Africa.

  • Reply to

    can it hit at least $1.25 tomorrow?

    by starteam003 Dec 2, 2014 8:52 PM
    rchites rchites Dec 2, 2014 9:09 PM Flag

    REREAD this little gem of a statement from the White House........ BARDA with FDA assistance is supporting the rapid scale-up and optimization of vaccine manufacturing for these vaccine candidates to ensure that the capacity exists to produce millions of vaccine doses in a timeyl way if mass vaccination campaigns are able to occur in 2015 in Africa. CATCH the (optimization) part....... OMG... , ZMapp’s antibodies are produced in specially grown tobacco plants and have only been produced in limited quantities. YESSSS and now they will be mass produced.. IT IS NOW A eIND...... Other clinical studies are slated to begin in affected African countries in early 2015. This therapeutic candidate has been used under an emergency investigational new drug (eIND) application in Ebola-infected patients in the United States, Africa, and elsewhere. Mapp Biopharmaceutical produces ZMapp. It could very well do it as nobody will sell now.......... I may buy some more in pre market if it don't spike.

  • Reply to

    one more thing i forgot to mention..

    by starteam003 Dec 2, 2014 6:25 PM
    rchites rchites Dec 2, 2014 8:01 PM Flag

    early retirement plan.

  • Reply to

    Hmmm NO AH for IBIO?

    by shipleych Dec 2, 2014 7:24 PM
    rchites rchites Dec 2, 2014 7:46 PM Flag

    1,000 shares just went through at .96. With the white house news this could jump tomorrow.

  • Reply to

    New Link Vaccine Elicits immune response!!!

    by schinzo123 Dec 2, 2014 7:10 AM
    rchites rchites Dec 2, 2014 7:24 PM Flag

    they could be a valuable customer as the animal antibodies go to plantibodies. Its a race and time is critical for the different companies making vaccines and cures. If you have listened to Robert and the 3rd Generation platform and technologies can make the difference. To be first would be a big plus for the animal antibody, protein companies. AGAIN IBIO does not have a vaccine or CURE............. They can help many of the companies that do have the serums ...............

CLNT
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