Come to think of it, my favorite yogurt and chocolate also comes from Switzerland! You don't think this is just coincidence, do you?
No question they have an NDA in place regarding Diabetes. Dr. Lowe's not mentioning it at all in his interview clearly indicates an NDA. Certainly at the least we should get diabetes data soon. There is also a decent chance of some kind of collaborative arrangement with one or more Big Pharmas.
Here is some of my history and reasons for believing that Amarantus might be entering into a MANF/Diabetes partnership, soon.
1) Watsonhelper and Bigbang and JP first introduced the idea to me. I didn't believe it though.
2) I asked Gerald in Las Vegas about why he hadn't commented on the grant Mart Saarma had received to study MANF/Diabetes. He said: "You won't hear me comment on that now either."
3) I told Gerald in Las Vegas that some people were saying that Novartis was researching MANF/Diabetes. And he said: "Yeah, people know that. But you won't hear me comment on that, either." (Laughing)
4)Gerald then told me of our clinical trial with Generex....and I said "Yeah, but they stopped it." He said, "No, we stopped it." I don't know why Gerald brought up the Generex trial in this context, but he did as if he were giving me a clue, but I still don't know what to make of it.
5) At the LA Conference I asked Gerald if a sub-set of Diabetes might qualify as an orphan? I said "wolf...wolf?" I couldn't remember the name. He said: "Wolfram's Syndrome?" I said "Yes, that is the one. It is probably so small though that you could never get a large enough group together to do a clinical trial on it." Very animated he said: "Oh no, we know where everyone in the world lives that has Wolframs. They are a very tight knit community. It would be very easy to do a clinical trial on them!" (He announced two weeks later that we were licensing Dr. Urano's invention on Wolframs)
6) Gerald told us a month ago he would be announcing some "diabetes data soon."
7) In Dr. David Lowe's interview a couple weeks ago the interviewer asked him about MANF. Dr. Lowe glowingly talked about every indication of MANF except....Diabetes/Wolframs!! (He went out of his way to not mention it.
8) Zoomboom's email from Dr. Saarma about his releasing some MANF/Diabetes data in April.
9) Dr. Urano's blogs about how MANF had tested positive and they were looking for a Big Pharma collaborative partner.
Maybe if MANF/Retinitis were in clinical human trials there would be a chance Boone Pickens could have become a participant in those trials, but we haven't even submit an IND yet to the FDA to start the process.
august: Excellent post! I think you are right. We are going to be walking through a land mine field for the next two years. It's so important we have people with experience guiding our footsteps.
Professor Fuller: Don't forget to mention your disdain over everyone's else's lack of RESEARCH! That is your alias' distinguishing characteristic..."the angry under appreciated PhD." I've noticed you've soften up the last day or so and are sounding more and more like "bankerboy". To be an effective basher you need at least a dozen well defined, iron clad, different aliases! Yours all seem the same after awhile.
Hey I think that this test looks even closer to our test than the one you tweeted. What do you think?
In summary, the bill that was past and the finding of this code suggests LymPro is on track to get reimbursement...as Gerald hoped? Why does this increase LymPro's Net Present Value? Gerald said it would speed up the regulatory process by 18 months. Why?
So perhaps this is the code Gerald found back in December and they are in the process of amending it now for reimbursement with LymPro? Cool. Nice jobs guys!
Zoom: Gerald told us about the codes...so you have found the actual code number...confirming it. But, was it in doubt? I saw you mentioned Quest.
gary: Trust me, I'm not going anywhere. I just feel safer then I'm asking the toughest questions I can. That's how I get my bearings. I do wish management would disclose more. But like everyone else, I see indirect evidences that LymPro is moving along: the hiring of new people, Gerald's saying they have confirmed previous results, etc. I appreciate your finding that CLIA regulation and emailing Aimee about it. That was helpful.
You and bankerboy are the only ones that interested in me. My wife isn't even as interested in me as you are! For being such a smart, busy, researcher....you sure seem interested in spending your time talking to me. That's pretty weird!
Sorry if I mistook you for Bankerboy. You undoubted must have a prestigious background in biomed stocks. I just got confused because you've come off as such a jerk. You must be really smart and a really good researcher and so super busy doing important things to justify you being so arrogant! I won't waste any more of your time.
mkeeryfuller: You remind me of someone i know: Bankerboy, Bigbuffoon, Coldcoffee, & Bigbang. Your new alias' theme is the arrogant PhD with a chip on his shoulder routine, utterly disgusted with people more successful than himself. Good one.
jpcalm: Excellent post! I think I am asking the right questions and I hope your answers are correct! I don't think we should become complacent. Placing greater trust in David Lowe than Robert Stern is probably the right choice, but not by much. AMBS is in a good place with LymPro, no doubt, but there are landmines in the terrain we have yet to travel. (Further testing to be done, Reimbursement, FDA approval, etc) That's the case with all pioneering, but I'd rather be here than in Georgetown's place.