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Puma Biotechnology, Inc. Message Board

rniesen77 68 posts  |  Last Activity: 1 hour 41 minutes ago Member since: Mar 15, 2013
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  • Sage advice.

    Sentiment: Strong Buy

  • rniesen77@gmail.com rniesen77 1 hour 55 minutes ago Flag

    New Report -- PennyStocksWeekly does no DD and can't be trusted!

  • Reply to

    QUESTION TO THE TECH SAVY

    by pdb3838 Jul 10, 2014 1:01 PM
    rniesen77@gmail.com rniesen77 1 hour 56 minutes ago Flag

    Related -- took this from the Motley Fool article on the topic:

    3D Systems (NYSE: DDD ) told analysts at its investor day event last Tuesday (Published Jun-18) that it expects the high-speed, continuous fabrication-grade 3-D printing platform that it's developing for Project Ara to be 50 times as fast as current systems. And now the largest 3-D printing company by market cap has released more details about its super-speedy platform -- as well as a video.

  • Reply to

    QUESTION TO THE TECH SAVY

    by pdb3838 Jul 10, 2014 1:01 PM
    rniesen77@gmail.com rniesen77 4 hours ago Flag

    Here is what little I know:
    A) EMB works at a higher temperature and is split into 50 beams.
    B) DDD has a video showing that they are working on speeding up laser-sintering by running the bed beneath a series of nozzles, i.e., like a race track, so there is more than one way to speed things up.
    C) This is a European initiative that Arcam is part of that is focused on speeding up printing by at least a factor of 50.
    D) HP says it is focusing on speed and quality for its entrance into the market.
    E) GE's Morris said in his speak at a conference in Dec. 2013 that they were current focused on DMLS, most likely EOS's machines, because the intricacy of the spaces within the LEAP engine nozzles makes it difficult to get the powder out.

    All of the current technologies will still be in use 10 years from now. It is like an arms race. They will all keep improving because each one has its strengths and weakness IMO. However, the most money is being spent right now on perfecting DMLS because Arcam is the only significant player using EBM -- their focus appears to be medical. GE is likely to buy many different printers, but my bet is EOS is their primary supplier as it always appears in their videos, they appear to be in the lead, and because Sigma Labs just acquired their printer for testing their IPQA product suite -- they are intertwined with Morris to optimize GE Aviation's the printing process. Most analysis favor SSYS in the short term as you know, but their chart has its issues. Everyone is pressing for additive manufacturing to become a production line so that is where this is heading. It will get there much faster for specialized, low volume, high-cost items than it will for the opposite.

    Sentiment: Strong Buy

  • rniesen77@gmail.com rniesen77 4 hours ago Flag

    Buy on rumor, sell on news!

  • Reply to

    Product Launch?

    by author1976 4 hours ago
    rniesen77@gmail.com rniesen77 4 hours ago Flag

    I did a search on the event named on ONVO's site which is described as being dedicated to one individual, Yuichi Sugiyama. From the website of his laboratory, see below, it is clear he is a KOL in the optimization of early-stage clinical decision making; an ideal individual for ONVO to use to evaluate their tissues. The event could yield another key endorsement of their tissue being superior to what exists now ... or not. Let's hope it is.

    Description of Sugiyama Laboratory: Yuichi Sugiyama (Ph.D.) Head

    "Many drug candidate compounds are synthesized in the early stage of a drug discovery. For these drug candidates, binding affinities to the target molecule (related to pharmacodynamics), rates of metabolism and membrane permeabilities (related to pharmacokinetics) will be studied by in vitro experiments. By comparing the various parameters obtained in these experiments, drug candidates will be selected and introduced into clinical trials. However, efficacies expected from animal experiments and in vitro experiments are not always reproducible in clinical trials, and it is also true that most of drug candidates drop out before the market. Since clinical trials require a lot of money, it is very important to select good drug candidates before going to the stage of clinical trials. RIKEN established Sugiyama Laboratory to promote the construction of an integrated support system for efflcient drug discovery. In Sugiyama Laboratory, we will establish a new methodology to select a reasonable drug candidates in the early stages of drug discovery. In particular, mathematical models that incorporate parameters obtained from a variety of in vitro screening will be constructed, which can be used for the quantitative simulation of pharmacokinetics and pharmacodynamics."

    Sentiment: Strong Buy

  • rniesen77@gmail.com rniesen77 Jul 1, 2014 11:33 AM Flag

    As other 3 D's are running up it is typical of SGLB to lag and then jump. Check out the weekly chart yourself and you will see. We are entering an interesting time for them because many of the moves they have made a scheduled to pay off between now and the end of the year therefore I am holding on for what I expect to be multi-bag upside when they go from a non-revenue (essentially) company to having significant orders.

    Sentiment: Hold

  • Reply to

    RE:would google take these guys out ?

    by nordiqqwolf Jun 30, 2014 2:45 PM
    rniesen77@gmail.com rniesen77 Jun 30, 2014 4:22 PM Flag

    Sorry, I was thinking Apple because they are most associated with InvenSense right now but the logic would be the same for Google unless the wanted to deny Apple access.

  • Reply to

    RE:would google take these guys out ?

    by nordiqqwolf Jun 30, 2014 2:45 PM
    rniesen77@gmail.com rniesen77 Jun 30, 2014 4:21 PM Flag

    Apple's only reason would to be to create a proprietary moat using Invensense's chips, but that is probably not what they are thinking. It is the Apple product-sphere or ecosystem that they compete with. Why buy when you can keep your supply chain fresh by keeping your options open?

  • Reply to

    Microsoft's new smartwatch

    by marmike80 Jun 30, 2014 10:24 AM
    rniesen77@gmail.com rniesen77 Jun 30, 2014 4:19 PM Flag

    Wall Street Journal is betting their reputation on a multiple model release of iWatchs this fall.

  • rniesen77@gmail.com by rniesen77 Jun 30, 2014 4:16 PM Flag

    Can anyone verify what I read in a comment to a posting on Friday that there are more KOLs working on reports for ONVO? Just a point in the where to look up this company commment. Thanks.

    I doubled down today. I hope other will too!

    Sentiment: Strong Buy

  • Any insight into why ONTX took off in the last 45 minutes of trading? Was this shorts covering or is something brewing? Please share!

    Sentiment: Strong Buy

  • Reply to

    SGLB Scam Report Released

    by britaneyvernizzivev May 31, 2014 11:54 PM
    rniesen77@gmail.com rniesen77 Jun 24, 2014 4:07 PM Flag

    Someone wrote this exact same things months ago. Your scamming tripe is not even fresh!

  • Reply to

    EOS Machine Cost

    by kmey3434 Jun 24, 2014 10:18 AM
    rniesen77@gmail.com rniesen77 Jun 24, 2014 4:06 PM Flag

    I would not expect Sigma to pay outright, at least not the full amount. My guess is that they bartered their technology for a discount or other favorable terms (lease amount) because if their technology is tightly integrated it would be a selling point for EOS machines. Just a guess however. Regardless they still are in a good cash position.

    Sentiment: Strong Buy

  • 1) Demonstrating to customers exactly how PrintRite3D works -- w/o a printer of their own this would be difficult and time consuming.
    2) Revenue -- while Sigma isn't large enough to compete with the large service bureaus they can certainly generate revenue for themselves offering to produce highly specialized parts for aerospace, aviation, and other extreme tech applications. Think of the bump up if SpaceX, who uses EOS printers to produce their SuperDraco rocket engines, let it be know they use PrintRite3D!
    3) R&D -- PrintRite3D testing will certainly be sped up by having their own printer to work with.
    4) Partnering -- EOS is a clear leader in the metals space. By employing their machine Sigma can build a direct relationship with EOS that could lead to EOS offering PrintRite3D on new purchases. They can also share intelligence on where innovation has to develop and steer their directions together.
    5) Enhances their role in industry programs -- with their own printer they can contribute more to industry programs, receive higher grants for doing development work, etc.

    These ideas are just top of mind, but it shows me despite how small of a company they are, they are thinking out of the box, continue to demonstrate they can "hit above their weight", and are progressing ever closer to commercializing PrintRite3D.

    Sentiment: Strong Buy

  • Reply to

    Carefully worded. Was it bought and how much?

    by pierre_narusse Jun 19, 2014 11:51 AM
    rniesen77@gmail.com rniesen77 Jun 20, 2014 12:25 PM Flag

    pdb3838 -- if you have read my other posts you might consider that they worked a deal with EOS. They are both serving the same customers and hence may find mutual benefit in exchanging technologies or at least providing each other the chance to work with each others equipment. Regardless, this demonstrates that Mark is taking steps to commercialize PrintRite3D. He has to have a way to show customers how it works and what stats they can expect. Without their own printer that would be hard. Second, by providing printing services they get revenue and allow customers to see how PrintRite3D can enhance quality and save time and cost.

  • Reply to

    So are they now becoming a Protolab competitor?

    by minhan64 Jun 19, 2014 12:35 PM
    rniesen77@gmail.com rniesen77 Jun 20, 2014 10:42 AM Flag

    IMO Sigma is too small to compete with any established service bureau like Materialize, Protolab, Shapeways, etc. My guess is they want to speed up development of PrintRite3D by having their own machine to work on as well as demonstrate to the many new customers that they will have to start showing it to starting in the next couple of months. They can't just walk customers into GE or Honeywell. However, EOS machines are costly so they will differ the cost - i.e., may operate at a loss - by producing highly specialized parts (read -- difficult to produce even for a 3D printer) in small quantities for industry. The patter goes something like this ... hey Rolls Royce, let me produce your most difficult part on my EOS machine so you can see exactly the data we can provide your from PrintRite3D. This will give you a specific cost savings estimate as well as demonstrate how quality will improve. We will only charge you what it costs you today to do it.

    It ultimately means to me that they are progressing SERIOUSLY toward commercializing PrintRite3D.

    Sentiment: Strong Buy

  • Reply to

    Carefully worded. Was it bought and how much?

    by pierre_narusse Jun 19, 2014 11:51 AM
    rniesen77@gmail.com rniesen77 Jun 20, 2014 10:33 AM Flag

    If I was Mark Cola I would negotiate a deal with EOS. Develop PrintRite3D on an EOS machine together with them and then market it together as the best metals printing machine in the world with the only IPQA. This is just speculation, but if it demonstrates a partnership developing between the two companies I would be hard pressed to suggest to Sigma a better manufacturer which I am sure they already know.

    Sentiment: Strong Buy

  • Reply to

    Carefully worded. Was it bought and how much?

    by pierre_narusse Jun 19, 2014 11:51 AM
    rniesen77@gmail.com rniesen77 Jun 19, 2014 12:02 PM Flag

    I do not know, but you may put a message into the company to ask. I don't think they would announce it, however, if it wasn't true. They are very well plugged into to market community that EOS provides to, especially GE Aviation which uses their machines extensively. You can always wait to buy in on the pullback if there is one.

  • Reply to

    buy why?

    by moorthiusa Jun 12, 2014 11:25 AM
    rniesen77@gmail.com rniesen77 Jun 19, 2014 10:56 AM Flag

    Got it.

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