David - I'm sure there are many things you want to include in your article, but I think you should try to stress very strongly the positives of not having acetaminophen. This usually gets mentioned briefly (when it is at all) in terms of liver toxicity. But liver toxicity over a long period of time is not the only problem with acetaminophen. Many people have medical conditions that make acetaminophen harmful even with short term use. For example, acetaminophen can cause internal bleeding in people with ulcerative colitis and other gastrointestinal disorders. I believe acetaminophen use is discouraged among people with renal insufficiency also. I'm sure there are many other examples, and I have read testimony from many doctors who feel strongly that acetaminophen-free options need to be available in the pain management field.
Well - it's just a thought. Good luck with your writing.
Skeesby, thanks for tipping me off to SYN. I took a small position immediately, and it looks good already.
And Mr. Kirk just bought some insane number of shares, so I feel like I'm in good company.
Green or not, I think it's held pretty strong since the huge run up. This isn't acting like a pump and dump, in my opinion. I've seen those go into straight vertical drops after the pop...this is acting different.
I got in a bit too high, but I plan on holding on to this and see what happens.
I totally agree with you about the direction of the price being tied to enrollment. But you're also saying that the enrollment and eventual Firdipase approval is very likely and I agree with that, too. And if you believe that, i think we're clearly talking a triple from here, or even more. That's a much less dour negative outlook that Mr. bigred is projecting. That's all I'm sayin'.
Ha, ha...right on, SL. I did the same, although I didn't pull the trigger at $9.80. I'm a little annoyed with myself about that.
I understand what you're saying. If you go by their statement, it's a much looser guideline than December 31. Hopefully, if we go into next year a bit, it won't be perceived as a problem.
Smart move? Hmmm....
Well, even if they don't meet the deadline and we take a hit, I think they will successfully get enrollment for these trials eventually, and we'll head back up again, at least to 5 sometime next year. So it would seem that it's not a bad risk.
I guess the real risk isn't the deadline, but the unlikely scenario of failing to enroll for months afterwards.
That seems REALLY unlikely, for the reasons I gave before about desperation. It's a very serious condition and the treatment is pretty much known to be effective, so who wouldn't jump at the chance? Jacobus is helping less than 10% of the US population, and their product is inferior. It seems crazy not to go with CPRX.
But the population is so small, it makes a quiet, behind the scenes "pressure campaign"
possible. I would like to have a better idea of how LEMS sufferers and their doctors are perceiving this whole situation. Are people buying into this "CPRX is the villain" nonsense? Are possible participants being pressured not to step forward?
Does anyone have any feeling for this? Are there online LEMS support groups with message boards, or things like that? I'd love to hear from some actual patients.
I seem to recall one person showing up here on our board claiming to be a patient, but he wasn't making much sense, as I recall.
Anyway...even if you wait for the enrollment announcement and miss an initial pop, you're likely to make major profits afterwards, and it's less risky.
Sorry for writing so much - too much caffeine!
I bought some AVNR right before earnings. It's been a crazy ride, but I'm hanging on.
I can't add much of value to what the veterans have to say here, but I have some courtroom experience, and I'm surprised at the disrespect being shown to Judge Stark by the plaintiff. That's not going to work out too well for them, in my opinion.
I don't understand the gist of your comment. Are you suggesting that because they said it would be done by the end of the year that it will be? That seems a little too complacent, if that's what you mean. I'm a little concerned about missing this deadline, and how it will be perceived. I have some personal experience with clinical trials, and I know that people with serious unmet medical needs are absolutely desperate - frantic sometimes - to get into trials that might help them. So that makes me believe that enrollment will be met easily. But on the other hand, we're dealing with a very uncommon condition, and that might make it hard to round up enough participants. Also, CPRX has been made out to be the "bad guy" (unjustly, in my opinion) and I hope that's not preventing people from stepping forward to participate.
I think it's clear from my post history here that I'm a supporter, and not a basher. I'm just presenting my concerns honestly. One thing I'm sure of - if they release a timely PR that enrollment has been met, we'll start a rocket ride up that won't stop for a long time.
If the information on this board about the JP Morgan presentation is correct, we might get a boost from that in mid-January. A little warm-up for the earnings, hopefully.
I hear ya. It's very frustrating. I might have bailed out today, but it's a down market day and I thought I'd give it a little more time. Good Luck.
AVNR is getting massacred every day, day after day. But they have a court case coming up - patent issue - and if they win, there will be quite a bounce. Any gamblers out there might want to look at those bargain prices and think about it.
in order to get involved in a class action lawsuit.
"I'd like to put the presents under the tree, honey, but this is the DEADLINE!"