Thu, Apr 17, 2014, 2:27 PM EDT - U.S. Markets close in 1 hr 33 mins

Recent

% | $
Quotes you view appear here for quick access.

Rosetta Stone, Inc. Message Board

rrtzrealmd 173 posts  |  Last Activity: Mar 24, 2014 11:10 AM Member since: Aug 24, 2011
  • rrtzrealmd rrtzrealmd Feb 15, 2014 2:02 AM Flag

    ...HAW!!!...the ONLY two things that Raptor has sold in its 10 plus years of existence are "jack" and "sh_t"...HAW!!!...they may THINK they're going to charge a quarter mil a year for "Procysbi," but when the insurance companies have a choice of "cystagon" at only $8,000 a year, I kinda suspect patients are just going to have to put up being unable to sleep all night without having to go to the bathroom...

    ...and as far as QCOR, it shouldn't take long for synacthen to gain FDA approval -- especially with so many patients and docs griping about the buttrape QCOR is attempting on patients...then QCOR will move rapidly back to the sub-dollar zone where it so deservedly belongs...HAW!!!...

  • Reply to

    The curious case of RE-021...

    by rrtzrealmd Feb 14, 2014 8:44 PM
    rrtzrealmd rrtzrealmd Feb 15, 2014 1:15 AM Flag

    ..."Focal Segmental Glomerulosclerosis (FSGS) is a disease that affects the kidney’s filtering system (glomeruli) causing scarring and loss of large amounts of protein in the urine."...satisfied?...

    ...and one of the odd things is that they AREN'T devloping it for hypertension since it has ALREADY completed phase 2 trials for that...I presume someone at Ligand felt it wasn't worth it...too bad for RTRX since there is a whole LOT more hypertensive disease than there is glomerulosclerosis...

    ...not to mention that they've found the agent thta triggers the cascade leading to the disease -- "suPAR" aka "soluble form of the urokinase plasminogen activator receptor"...plus the FDA just last year approved a device that can be used to treat patients that don't respond to the standard therapies -- the "Liposorber LA-15 System...although the study was small, the gizmo proved remarkably adept at inducing remission of the disease...but then, you probably already knew all that, huh?...

  • Reply to

    $4.19M Private Funding

    by profitzone Feb 13, 2014 12:12 PM
    rrtzrealmd rrtzrealmd Feb 14, 2014 9:36 PM Flag

    ...HAW!!...yeah, the fun begins for MANAGEMENT!...they've got a few million more to pay their salaries, benefits, bonuses and perks...as shareholders watched their ownership get diluted and the stock price dropped 20%...HAPPY DAYS ARE HERE AGAIN!....HAW!!

  • Reply to

    A number came to my mind for ORMP

    by yinvestor Feb 14, 2014 3:55 PM
    rrtzrealmd rrtzrealmd Feb 14, 2014 9:32 PM Flag

    ...some time ago, a number came to mine as well...the day I first read the stuff on page 14 of Orascam's website, the number that came to mind was ZERO...

  • rrtzrealmd rrtzrealmd Feb 14, 2014 9:30 PM Flag

    "My guess is most got out long before or at the point of the 1 for 11 split."????...oh, you're "guessing" now?...well, let's say someone DIDN'T get out, and today they sold the 100 shares of ENMD they bought on January 31 of 2000, and you called them up and asked them how much they LOST on the transaction -- tell me now, what would they say the total loss was...feel free to "round off"...

  • rrtzrealmd rrtzrealmd Feb 14, 2014 9:20 PM Flag

    ......you keep talking about dividend growth...

    ...first, that ignores another key element -- shareholder equity...CCG is trading at about a 10% discount to book value...compare to ACC and EDR trading at about a 40% PREMIUM to book value...

    ...second, even if you want to focus on dividend growth, CCG has not been "basically" flat...it has increased its dividend by $0.038 since its IPO while ACC has increased its dividend by only $.022 during that period of time...and BRE increased its divi only $0.02 in that time...so it's not exactly "lagging" in that department...

    ...also bear in mind that CGG's IPO was only about three years ago, so it's not like it's had a long time to establish a dividend history...besides which, they invest a great deal of cash flow in construction projects which hopefully will translate into significant future dividends...also, I would rather they exercise caution in managing the dividend early on -- given what happens when an REIT announces a dividend cut...

  • ...originally it was developed by Bristol-Myers...in 2006, EIGHT YEARS ago, it was part of a group of compounds they licensed to Pharmacopeia...Pharmacopeia ran phase 1 and 2 trials as a possible treatment for hypertension...two years later, Ligand came along and bought Pharmacopeia for 70 million dollars...

    ...for the next FOUR YEARS, Ligand -- probably recognizing what an expensive black hole further development of sparsetan (aka RE-021) would be, totally ignored it -- UNTIL along came RTRX who acquired a license for it...

    ...and now:

    "Ligand will receive a net upfront payment of $1 million, and may receive, net of amounts owed to third parties, over $75 million in milestone payments based on clinical and regulatory progress as well as 9% in royalties on potential future worldwide sales by Retrophin."

    ...hmmmmmmmm...isn't it more USUAL for the tiny biotech to receive the "upfront payment" as well as the milestone payments from the bigger company for maneuvering a drug through trials?...

    ...as it is, RTRX investors won't start making a dime until profits from sales tops $76 million -- an event likely to occur about the same time that pigs start flying through snowstorms in Hades...HAW!!!...

    ...I accidentally posted this earlier as a reply to a question about RE-024 -- that was not spamming, just a mistake on my part.

  • rrtzrealmd rrtzrealmd Feb 14, 2014 8:35 PM Flag

    ..."Why does SRPT have a billion dollar mcap with no revenue and phase 2 data in only 12 kids?"????...hmmmmmmm...probably because the average biotech investor has the IQ of a grapenut...HAW!!!...

  • rrtzrealmd rrtzrealmd Feb 14, 2014 8:33 PM Flag

    ...PLEASE IGNORE my previous post which is about RE-021and FSGS, NOT about RE-024 -- which is aimed at PKAN...

    ...in answer to your question.RE-024 apparently has undergone NO human studies yet...

  • rrtzrealmd rrtzrealmd Feb 14, 2014 12:31 PM Flag

    ...well, so far they've only shown it works in MICE that have been treated to MIMIC a PKAN phenotype...and there is a WIDE gulf -- think in terms of the distance from earth to "z8_GND_5296" -- between some poisoned varmint and a real live human being with a true genetic abnormality...you might want to consider that before believing that some hedge fund manager is going to be able to pull a magic rabbit out of his hat...

  • rrtzrealmd rrtzrealmd Feb 14, 2014 12:24 PM Flag

    ...??????...do you even understand how CCG works?...

    ...first, in terms of the dividend growth, compare growth to EDR and ACC and you'll find they're roughly the same...not to mention that CCG's yield is 50% higher than either one of those...

    ...second, note that CCG builds a lot if not most of its facilities -- consequently, one reasonably expects increasing debt...indeed, that's the basic idea, isn't it?...borrow at a fixed rate and then collect at a higher adjustable rate?...that's why you won't need to worry so much about "higher interest rates in the future"...

    ...third, note that CCG's adjusted FFO has DOUBLED in the past year -- "adjusted" to exclude the write-off of unamortized deferred financing fees, transaction costs and fair value debt adjustments on equity method investments...that's a better figure to follow for CCG...

    ...finally, note the recent rally in ACC after its earnings report -- an indication that there might substantial rewards ahead for CCG as well...

  • rrtzrealmd by rrtzrealmd Feb 14, 2014 11:51 AM Flag

    ...mediocre products and amongst the worst customer service...I bought some funny teeshirts and hoodies for my kids at christmas -- after ONE washing they are so faded you can barely read what's on them...I bought a few other things that turned out to be "junky" made in china -- where else, right? -- stuff...I suspect PRSS will need a major overhaul in order to succeed...

  • rrtzrealmd rrtzrealmd Feb 14, 2014 11:40 AM Flag

    ...HAW!!!...you posted the same thing TWICE in a row????...what was the matter -- upset by something I said?...gee, bagholders sure are a sensitive bunch!...HAW!!!...

    ...I suppose IGNORING the 1 for 10 reverse split allows you to say that -- in ONE sense -- no one ever paid over a $100...but the FACT remains that ONE share bought at the high of the year 2000 has LOST -- calculator please! -- 99.8 per cent of its value!...

    ...of course, that's "if one stupidly" bought the thing in the first place!!...and THEN "held on"...HAW!!!!...

  • ...dang!...try saying that three times in a row real fast!...HAW!...anyway, I see the frequency of this disease is about ONE in a MILLION!...whooeeeee!...that makes the total number of patients in the US around -- what -- 200 , give or take..
    .
    ...200????...ain't it going be kinda hard to make any money off a drug for just 200 people?...well, what's a few shareholder bucks when you're trying to do domething noble -- right?...

    ...and RTRX thinks this RE-024 has potential because of this:

    "Retrophin, Inc. (OTCQB: RTRX) today announced that it has received positive survival results from interim preclinical tests for the Company's compound, RE-024, for the treatment of the ultra-orphan disease Pantothenate Kinase-Associated Neurodegeneration (PKAN).....Tests were conducted on mice that were administered a PANK inhibitor to induce a PKAN-like phenotype....The interim results of this two-week study assessed the effect of RE-024 in mice...(37/40) of the mice..."

    ...now, let me get this straight -- RTRX is planning on spending who knows how many millions of shareholder equity on an "ultra-orphan" disease based on a TWO WEEK study of FORTY MICE that were INDUCED to have a "PKAN-like" phenotype -- in other words, they didn't even have the mutation in the PANK2 gene?...is that about it?...hold on a second:

    HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW!!!!!

    ...oh, that's a good one!...but be a whole lot easier just a take pickup filled with hundred dollar bills down to the landfill and dump'em!...HAW!!!...

  • Reply to

    Will wonders ever cease...

    by rrtzrealmd Feb 14, 2014 1:48 AM
    rrtzrealmd rrtzrealmd Feb 14, 2014 1:51 AM Flag

    ...oops!...my mistake!...they're actually spending 62 MILLION -- not 52 million...sorry, I was laughing so hard, the tears must have obscured my vision...

  • ...a two bit biotech -- two bits actually being a very generous assessment of the value of its stock -- goes out and commits to spending 52 million dollars -- even though they're probably near broke -- to buy a company that likely has less than 10 million in revenues -- given that either no one uses the drugs they offer or else there's maybe only 20-30 patients with a disease the drug can treat...

    ...is that about the size of it?...hold on a second while I get this off my chest:

    HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW!!!!

    ...whew!...I feel much better now!...

    ...well, let's see, per the last 10Q, RTRX lost 20 MILLION dollars in the preceding nine months -- typical biotech...ten MILLION of that was in just the preceding three months -- probably issuing bonuses to management...about 15 mil in cash at the time -- but burning 3-4 million a month means by NOW they must be just about BROKE!!!...

    ...why, makes perfectly good sense!...broke, losing money hand over fist, no prospects for improving cash flow anytime in the near future -- how are we going to justify a SECONDARY OFFERING?...

    ...oh, wait!!...I know!...I know!!!...call on me!!!...ahem!...let's go out and spend a fortune buying another near worthless company!...that'll justify a SECONDARY and let us rake in some extra cash just in time for BONUSES!...there's a motion on the floor -- all approving say, "aye"!...AYE, AYE, AYE!!!!!!!!!!...the motion is carried!...now, excuse me, I have to run down and pick out a color for my new Mercedes...HAW!!!!!...

  • Reply to

    How are they paying for this deal???

    by t0psecret.leader Feb 13, 2014 9:40 PM
    rrtzrealmd rrtzrealmd Feb 14, 2014 1:31 AM Flag

    ...why, son, don't you realize this is a biotech?...can you spell the word S-E-C-O-N-D-A-R-Y?..HAW!!!!

  • Reply to

    HAW!!! Still reading the 8K...

    by rrtzrealmd Feb 13, 2014 11:14 PM
    rrtzrealmd rrtzrealmd Feb 14, 2014 1:26 AM Flag

    ...awwwwwwww --- what's the matter, bunky?...you got the BAGHOLDER blues or what?...HAW!!!!...

  • rrtzrealmd rrtzrealmd Feb 14, 2014 1:11 AM Flag

    ...all you gotta do is click the ENMD graph on this page...then -- presuming you didn't faint from the intellectual effort required on your part to do that -- click on the "max" button on that graph and look at the year 2000...you can right click on the tippy tippy top of that spike and it will tell you the closing price for day...on January 1st of 2000, the SUCKERS lined up and traded 1,093,719 shares...and the closing price was:

    ONE THOUSAND AND EIGHTY THREE DOLLARS AND FIFTY CENTS!!!!!!!!!

    ...or $1,083.4892 if you want to be picky!...HAW!!!...

    ...let me whip my little calculator a second...hmmmmmmm...that means that around 1.2 BILLION dollars changed hands that day!...say, what's ENMD market cap now?...

    ...anyway, from there on, it was NOTHING but a trail of tears all the way...bagholders to the left!...bagholders to the right!...bagholders up, down and all around the town!...

    ...and through it all, there were always a few CHUMPS on this board trying to defend ENMD...I still remember "cancerkills" badmouthing my posts about what a pathetic scam ENMD was and how their data was as phoney as a three dollar bill -- ahhhhh, the good ol'days...I wonder whether cancer ever did kill him -- sure as hell nothing from ENMD ever cured him!...HAW!!!!...

  • ...just filed which has a presentation in it...they finally get around to revealing the "unique indication" they are seeking approval for:

    "Focused on reducing the excessive nocturnal glucose production from the liver"

    ...ta-da!!!...aren't you impressed?!...away with all that nonsense about enabling diabetics to discard their needles!...we now know that ORMP is aiming to control liver production of glucose at night!...

    ...hmmmmm...okay...why?...how exactly is doing that going to help the diabetic?...indeed, what kind of problems does "nocturnal" release of glucose cause?...hmmmmm...they don't appear to have provided an answer to that...

    ...and isn't it odd that -- as best I can determine -- ORMP has yet to do a trial where they just gave ORMD-0801 before bed?...or, for that matter, any trial where they measured nighttime glucose levels...ohhhh, but I'm sure that they'll get around to doing all that...at some point...maybe...but no doubt AFTER they've fleeced an adequate number of naive investors...then again, for most biotechs, there never seems to be enough naive investors...

RST
11.29+0.1400(+1.26%)2:22 PMEDT

Trending Tickers

i
Trending Tickers features significant U.S. stocks showing the most dramatic increase in user interest in Yahoo Finance in the previous hour over historic norms. The list is limited to those equities which trade at least 100,000 shares on an average day and have a market cap of more than $300 million.