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Fidelity National Financial, Inc. Message Board

rrtzrealmd 171 posts  |  Last Activity: Mar 24, 2014 11:10 AM Member since: Aug 24, 2011
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  • ...that Orascam submitted on the recent 8K...they say at one point, talking about type 2 diabetics:

    "Elevated FBG levels are a major issue in T2DM...main cause: excessive nocturnal glucose production from liver...Current treatments for correction of elevated FBG are suboptimal"

    ...HAW!!!...well. let's see, elevated blood glucose levels are the problem, period, in diabetes 1 or 2, fasting or otherwise...the core issue being the failure of the body to utilize the glucose due either to lack of insulin (type 1)or insulin resistance (type 2)...

    ...the "main cause"???...proof???...where I come from, the "main" cause is insulin resistance that arises in consequence of the fat #$%$ inability to stop cramming food down their gullets!...not to mention that insulin resistance is demonstrated bay BOTH fat and liver cells so delivery via the portal vein is not necessarily going to affect it...moreover, I can't find any evidence that portal vein delivery would improve outcomes period...in which case, the FDA would expect ORMP to shoulder the burden of demonstrating that an oral insulin would in fact produce better outcomes in treatment -- something that would likely require who knows how many hundreds of patients and who knows how many years....

    ..."current treatments...suboptimal"?????...hardly!...most current treatments work fine!...the sulfonylurea drugs enhance pancreatic islet sensitivity to glucose, leading to increased insulin secretion, suppression of hepatic glucose production, and a decline in the steady-state fasting glucose level and work just fine...unfortunately, the two BEST ones -- STOP eating so damn much and get off your lazy butt and EXCERCISE -- are the ones patients find difficult to comply with...

  • rrtzrealmd rrtzrealmd Feb 13, 2014 8:58 PM Flag

    ..."...was never a $918/share company"?????????????...begging your pardon, but you might want to click on the "interactive chart" and hit "max available"...In February of 2000, ENMD, one of the biggest biotech scams ever, traded at -- drum roll, please!...are you ready?...you might want to sit down or slip into some heavy duty depends before reading further!...a high of $1,083.50!!!!!!...

    ...yes, folks!!!...somewhere existed the BAGHOLDER "par excellence"!...THE bagholder by which all other bagholders are measured!...yes, there walked this earth in 2000 a FOOL dumb enough to chuck out ONE THOUSAND EIGHTY THREE DOLLARS AND FIFTY CENTS for an absolutely WORTHLESS stock...

    ...and which stock did he/she choose to achieve this acclaim -- ENTREMED!!...how about a big round of applause, please!!...thank you!...

    ...and remarkably enough, people STILL throw perfectly good money at ENMD stock even though it is still WORTHLESS!...well, except for its ability to enrich management and stockbrokers, that is...and somewhere P.T. Barnum sits with a large, satisified smile on his face!...HAW!!!!...

  • rrtzrealmd rrtzrealmd Feb 13, 2014 8:40 PM Flag

    ..."SCAM? get real this is business as usual in the Bio world."????...well, actually, it's fair to say that "SCAM" is essentially interchangeable with biotech -- at least on Wall Street...basically an amalgam of worthless companies that exist only to line management pockets and enrich stockbrokers...hardly a one will likely ever produce anything in this lifetime...it's thanks to naive, dimwitted, and otherwise intellectually insufficient investors -- take yourself, for example -- who are willing to buy such nnonsense that they continue to survive...

  • rrtzrealmd by rrtzrealmd Feb 13, 2014 8:02 PM Flag

    ...attracted some attention today...although, given that I am again the only one to post about it, it seems hardly worth discussing...

  • rrtzrealmd rrtzrealmd Feb 13, 2014 12:34 PM Flag

    ...HAW!!!...where do you get that "more advanced trial" nonsense?...have you looked at the presentation they filed in the latest 8K?...in the past SEVEN YEARS, they have dosed only 158 subjects...of those only 87 were diabetics...

    ...they also reported that the TOTAL number of doses given in those SEVEN YEARS was 1632 -- that is only about TEN doses per test subject, or only about THREE DAYS worth of treatment...in SEVEN YEARS...

    ...if you think Novo is going to pay "1.5" billion because of Orascam's "trials," you need a good psychiatrist and a couple of doses of haldol...

    ...not to mention that Orascam has yet to demonstrate any VALUE to their pill...won't get rid of needles they finally clarified...MAYBE will help type 2 diabetics if given "early" in treatment -- but don't provide any data supporting the claim...geez, a single sheet of USED toilet paper is worth more than this "company"...

  • rrtzrealmd rrtzrealmd Feb 13, 2014 12:23 PM Flag

    ...yeah, they also own a big wad of ECTYQ too -- and I presume you know what that "Q" means...not to mention significant chunks of INO, ITI, LRAD, DAEG, LTBR, OVRL, PEYE, PLUG, REMI, RGDX, TWOC, VRNM, CRMB, CDTI -- average price somewhere south of $2...no doubt ORMP will be joining that "club" in the not too distant future...

  • rrtzrealmd rrtzrealmd Feb 13, 2014 12:08 PM Flag

    ...Schwab may be more "thorough" but it still includes what they call a "momentum grade" which includes "analyst sentiment" and "price performance vs market"...so things pumped by analysts and outperforming the market get higher ranking -- in other words, stocks that are "popular" are favored while unpopular ones are "beat down."...

    ...they still don't give specific timing or buy/sell recommendations... and, as best I can determine, no one has reported any results from efforts at using their the system...I certainly can't find anyone bragging about their success with it...

  • ...on better than expected earnings...hopefully bodes well for CCG...earnings due in a couple of weeks...

  • rrtzrealmd rrtzrealmd Feb 13, 2014 1:38 AM Flag

    ...that's easy!...why not?...if they succeed -- great -- they make a lot of money!...if they don't -- big deal -- they pass the cost -- plus a little "extra" for "future research" -- on to YOU!...and when your health insurance bill jumps another 5% and your social security and other taxes jump, you'll be able to write Novo a note thanking them for milking you like a Wisconsin guernsey!...HAW!!!...

  • ...from the presentation submitted on the 8K filed today:

    "ORMD-0801 is NOT a substitute for insulin injections, but rather a new earlier treatment option."

    ...note that, although I can't show it here, the "not" was heavily emphasized in the presentation...I'm glad they finally cleared that up; I was tired of reading the assorted BS about diabetics being able to throw away their needles, etc, because of Orascam's "discovery"......

  • ...Orascam just filed an 8K with the SEC...I haven't yet read the whole thing...I got interrupted by falling out of my chair laughing at the graph that says -- you might want to slip into some comfortable depends before reading further:

    "ORMD-0801 Total Administrations to-date 153"

    ...so let me get this straight -- the sum TOTAL of test subjects in the SEVEN YEARS since the trials began is just ONE HUNDRED FIFTY EIGHT?...excuses me a second...

    HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW,HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW!!!

    ...the TOTAL number of type 1 diabetics given the pill -- in SEVEN YEARS, mind you -- was THIRTY SEVEN...the TOTAL number of type 2 diabetics given the pill -- remember SEVEN YEARS -- was FIFTY...the rest were "healthy subjects...

    ....so let me get this straight -- the sum TOTAL of ACTUAL diabetics tested over SEVEN YEARS jusr EIGHTY SEVEN?...sorry, I can't help myself...

    HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW,HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW,!!!

    ....but WAIT!...it gets better!...get this: "total number of human doses 1632"...??????...1632 DOSES????...ONE THOUSAND SIX HUNDRED THIRTY TWO???...DOSES???...in SEVEN YEARS???...

    ...so let me get this straight -- the SUM TOTAL of doses amounted to only about TEN doses per test subject, or only about THREE DAYS worth of treatment...ahem!...a moment please...

    HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW,HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW, HAW,!!!

    ...ahhhh! I feel much better...now I'll go on and try to read the rest...

  • rrtzrealmd rrtzrealmd Feb 12, 2014 12:00 PM Flag

    ...so many scams, so little time...HAW!...another Israeli company that reeks of con is DRIO which -- surprise, surprise -- has Itamar Raz -- as in GNBT Itamar and ORMP Itamar -- as "Head of the Scientific Advisory Board"...

    ...they claim they're going to market a device that plugs into your cell phone which will send glucometer data to wherever you want...wonderful -- the only thing is, there are already several other devices on the market that do the same thing WIRELESSLY automatically -- a detail that DRIO management never seems to mention...I'm sooooooooo disappointed at P.T. Barum's insight into human behavior....

  • rrtzrealmd rrtzrealmd Feb 12, 2014 11:42 AM Flag

    ..."Novo is wasting its time and money by being number two in this race..."...race???...what race???...I don't consider a 100 yard dash between a one-legged rooster -- aka Orascam -- and a greyhound -- aka Novo -- much of a race...

    ...and I don't think they are even in the "same development race"...the only thing Orascam is likely interested in developing is bagfuls of money for management and the Kidrons...

    ...as far as Novo wasting their time -- beats me...I do know that after SIX YEARS of phase 1 trials, Novo is STILL in phase ONE...they probably could care less, actually, since it accomplishes what they likely really want -- i.e. a good excuse to raise their regular insulin prices and boost profits...hmmmmm...come to think of it, maybe they are in the "same development race"...chasing the almighty dollar is so much more rewarding than helping diabetics...

  • rrtzrealmd rrtzrealmd Feb 12, 2014 10:35 AM Flag

    ...well, in this case, if you believe in the "proudakt," then consider yourself either very stupid or otherwise severly mentally incapacitated..."in the end u will get your money and more"???... well, I suspect all anybody dumb enough to buy the stock will get is exactly what GNBT and EMIS investors got -- and what they got in their "end" was very large and probably not even lubricated ...

  • rrtzrealmd rrtzrealmd Feb 12, 2014 10:28 AM Flag

    ..."an easy way to take insulin"???...well, yeah, IF it worked -- which it DOESN'T...which is why Orascam keeps trying to hide the data...they already admit the pill won't replace the needle -- of course it won't; the typical type 1 diabetic would need to take THIRTY to FIFTY ormd-0801 pills each DAY to meet their insulin needs...get over it already; ORMP is just as phoney as GNBT and EMIS...

  • rrtzrealmd by rrtzrealmd Feb 11, 2014 11:51 AM Flag

    ...from form 4 filed by Regals Capital Management:

    "On November 2, 2012, the Fund purchased units representing 405,405 shares of common stock and the 202,703 warrants described in this Form 4 for $0.37 per unit."

    ...dang!...I just gotta open me a hedge fund!...I reckon that there insulin wasn't worth much -- uhhhh, let's see -- fifteen MONTHS ago...HAW!!!...

    ...okay, okay!...I know they had a one for twelve reverse split after that...but it still means he paid $4.40 -- a pretty capital gain in just 15 MONTHS...but has Orascam's clinical situation changed -- no...the THREE phase 1 trials and FOUR phase 2 trials done between 2007 and 2010 are as useless as ever, evidently...and the new "trials" have added nothing substantive -- or at least nothing that the company is willing to prove by releasing data...

    ...the only other changes I could find were the prospectus for the "5,189,267 shares of common stock ..., filed February 1, 2013" to be sold for $7 a share -- what a difference a year makes, huh?...HAW!...

    ...then, of course, there's the more recent 100 MILLION dollar shelf registration...I imagine management figures to make hay while the sun is shining -- shining for ORMP management, that is!...or until investors find out what the data in those "trials" REALLY says about their insulin pill!...what was that?...I swear, I keep hearing howling every time I get on this board!...HAW!!!...

  • rrtzrealmd by rrtzrealmd Feb 11, 2014 11:07 AM Flag

    ...I got a kick out of this header which I nabbed from a post on the LGDI message board...someone here mentioned the purchases of ORMP stock by an "insider" identified as "Regals Capital Management"...well, it turns out that Regals is the "vehicle" of one "David Mark Slager"...

    ...although totally irrelevant, Dave was a graduate of "Haberdashers' Aske's Boy's School" -- I say, no doubt a jolly good school, cheerio and all that!!...HAW!!!...

    ...in any case, he was a partner in the Atticus hedge fund -- until it closed down after losing 43% of its value in 2008....not to worry though, since in earned 450 MILLION dollars in 2007 alone...(note to myself -- start a hedge fund!)...he then co-founded Attara Capital -- another hedge fund -- which was forced to liquidate in 2012 "as a result of adverse trading conditions and difficulty raising new money from investors"...not on a big winning streak, huh?...

    ...so what has this all got to do with my header?...welllllll...it turns out, for whatever reason, Dave got interested in an Australian "mining" company called "Legends International"(LGDI)...he ended up buying and/or owning around 100 plus million shares...he paid anywhere from a nickel to a dime a share and it currently is quoted at 3 CENTS...

    ...when Dave got involved there were about 200 million shares outstanding...two years later there are 400 million shares...in the meantime, assets dropped from 23 million to 18 million...there were quite a few transactions involved and, I dunno, I keep getting this image of Leonardo DiCaprio flipping the bird two-handed at a telephone and laughing...oh, well, in any case, I suspect Dave is one of those fortunate investors who does well no matter which way the stock price goes...consequently, I can't get real enthusiastic about his recent purchases of Orascam...

  • Reply to

    460 units of insulin per meal???

    by rrtzrealmd Feb 10, 2014 12:59 PM
    rrtzrealmd rrtzrealmd Feb 10, 2014 9:25 PM Flag

    ..." there have been 4 phase 2 studies since 2010 and none of the data from those have been published" -- the list is at the bottom of page 14 of Orascam's website; feel free to search for reported results because I sure couldn't find any...

    ..."How were they able to raise 16 mill in December?"...may I recommend a very educational movie called "The Wolf of Wall Street"...

    ..."...stock purchase made last week by their holding company"?...I'm not sure what you're referring to...are you talking about the reported insider purchase by "Regals Capital Management"?...if so, you might want to look at their other holding -- "Legends International Holding" (LGDI)...it's history makes GREAT reading...just google "Slager"(aka Regals) and "legends international"...also read LGDI's last 10Q and see how safe you feel about his involvement with ORMP...wait!...what was that?...I swear I just heard something that sounded like a wolf howling...HAW!!!...

  • Reply to

    460 units of insulin per meal???

    by rrtzrealmd Feb 10, 2014 12:59 PM
    rrtzrealmd rrtzrealmd Feb 10, 2014 2:06 PM Flag

    ...hba1c????...surely you jest!...have ANY of the trials lasted more than a week or two?...hardly enough to time to affect hba1c...of course, I'm not sure what the THREE phase 1 studies and the FOUR phase 2 studies done between 2007 and 2010 found since I can't find reports of that data published ANYWHERE!...

  • Reply to

    460 units of insulin per meal???

    by rrtzrealmd Feb 10, 2014 12:59 PM
    rrtzrealmd rrtzrealmd Feb 10, 2014 1:33 PM Flag

    ...Henry Schein charges $145 for 1000U of Humulin R --- that price is to hospitals and docs; I don't know what consumers have to pay...so figure the 460 units Oramed gave as costing around $70...if required to take three times a day, you get around $200...bear in mind that insulin dosing varies widely -- ranging usually from 30U per day to 70U in type 1 diabetics and 50U plus in type 2 diabetics...

    ...note that Oramed NEVER discusses this issue ANYWHERE -- they NEVER point out how many UNITS they are actually giving...they NEVER point out that what little data they offer in their trials suggests less than 1% absorption -- indeed, they NEVER discuss the efficiency of absorption at all...they NEVER mention the cost of the insulin being given...I'm really amazed at their audacity -- to claim they have an oral insulin and then put out PRs about releasing data -- but NOT release it -- and more PRs about trials -- despite the TEN or so "trials" they've already done...etc, etc...they make Generex look like a piker in terms of dis/mis-information...

    ...I know of no other mistakes, but I'm going to look at those two reports from their wesite again...I sort of skimmed the first time through because they were both clearly useless studies in terms of design -- that and the absurd amount of insulin in each pill -- they just weren't worth the effort...

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