buul ssshht !! FDA granted the Break Through Designation status for a reason.. because these compounds have NOT demonstrated statistical significance..
if it works so well as you claimed, why stock price is still in the mid $20s ? ..LMAO ..
your intelligence is horrible, you don't even know how to find this information on gxxgle.. "The literature is littered with examples of therapies that work well in mice but fail "
1. statements_by_scientists links
“This [over reliance on mice] has skewed the field so much that most clinically trained immunologists keep at least a few (and usually a lot more) mice in the “back room” so that they can have a steady flow of papers, grant funding, etc., and some have abandoned human work entirely as a lost cause. But this is just the price of progress, no? Well, except that mice are lousy models for clinical studies. This is readily apparent in autoimmunity and in cancer immunotherapy where of dozens (if not hundreds) of protocols that work well in mice, very few have been successful in humans. Similarly, in neurological diseases, the mouse models have also been disappointing.”
- Davis, MM, Director Stanford University Institute for Immunity, Transplantation and Infection. “A prescription for human immunology.” Immunity. 2008 Dec 19;29(6):835-8.
Mice are not always reliable as preclinical models for human disease and the scientific
literature is littered with examples of drugs that worked well in animals but turned out to be
ineffective in clinical trials on humans. These failures cost the pharmaceutical industry
millions of euros.
2.jimmunol dot org links
“The history of cancer research has been a history of curing cancer in the mouse … We have cured mice of cancer for decades, and it simply didn’t work in humans.”
- Dr. Richard Klausner, National Cancer Institute, LA Times, May 6, 1998.
if it is NOT about the CLDX, then should it be the competition ?
how is it good when too many drugs compete for small number of patients ?
publication in 2007 ? where is the FDA approval after 8 yrs of this article ? was you in the coma for the last 8 yrs ?
Many biotech companies found the failure in late clinical trials because :
When experiments are run in small animals like mice and rats, the immune therapy works well. In experiments with larger animals, however, you don't see the same effect. Don't bet your farm on this preliminary lab results ... GL
I'm an investor, not a biotech researcher nor biologist.. and don't wanne be one...
the problem with these "experts" in biotech field is that they marginally know enough to lose their money, but not smart enough to think logically..
why do you need to understand every cancer cell in human body before you can invest in Biotech company ? ...unless you're working for Celldex, you know nothing about CLDX either.. your knowledge is based on the information on the Celldex websites, and your knowledge is based on articles published by analyst's opinions... enlighten me...
thegreyfog, new week is not over yet.. are you still hang on to 2000 shares you bought yesterday at $29.38? CLDX PPS should be above $50 by next week.. don't give up your shares to MMs... you're very good of catching a falling knife.. LMAO...
huh ? CLDX dropped more than 18% for the past 3 days, and you think shorts going to need more luck ??? pass me what you're smokin'... LMAO..
paid pumpers are posting the similar message on every biotech MB, talking about M&A from BMY, MRK, PFE, SNY and other major pharmas.. hold on to your shares... price could pop 100% overnight when the M&A news is announced... poor retail investors who are not aware of these kind of activities by paid pumpers..
The worse thing is that they're not listening and not learning from their mistakes... because they only know "one trick pony" of how to make money.. LMAO...
typical boiler room's paid pumpers, they created confusion, misinformation and controversial to divert attention from the crisis at hand.. Same players with various screen names to calm down retail investors so they won't cut their loss and leave...
they encourage retail investors about buy 'n hold while they milk the cow dry... it is funny to watch these dump cows standing still while they're being scammed... LMAO..
it went up because the sunrise in the EAST...and it happened under the leardership of BHO.. does it sound right ? LMAO...
retail investors settlement date is 3 days, margin and wholesale investors settlement date is the same day..
"Daily short" data is for smart investors, "delayed short and IO" data is for "dump" retail investors who like to make big deal of outdated data..
Did you see that I said: "My daily short report shows shorts volume increased 5 days after the news announcement.."
Since you like to use outdated data to make your investment decisions, then let it be... why change ??? GL..
temp, you look for evidences to fit the crime.. you already made up your mind of how to interpret data that always favor long position, so there's no reason to talk about other data that may neutralize the short interest report...GL
CLDX get the FDA BTD on 2/24/15 and the secondary on 2/25/15, the NASDAQ short interest reported on Feb 27th, and it shows SI not lower 3 days after the announcement. That is the indicative of shorts have not covered after the news hit. My daily short report shows shorts volume increased 5 days after the news announcement.. what data do you have to show the linkage between the stock moves from 24.25 to 32 were due to short covered ?
Settlement Date Short Interest Avg Daily Share Volume Days To Cover
3/13/2015 17,737,036 2,385,254 7.436120
2/27/2015 21,498,843 3,394,334 6.333744
2/13/2015 21,275,300 1,295,008 16.428702
Read more: http://www.nasdaq.com/symbol/cldx/short-interest#ixzz3VMPKGrQe,
you pumpers are funny.. you claimed that high short interests is good because when the news hit, shorts covering will propelled stock price to the $40's and beyond...
Now short interests dropped, you say it is good news because "smart money is covering"... so I guess when the good news hit, stock price won't go up as much because lower short interests... is that it ????... LMAO..
watching videos ? no, that video were circulated around 12 yrs ago.. if you didn't watch back then, you must live in a cave... that kind of manipulating techniques were ancient and for newbies only.. smart investors accept market manipulation is part of the game and they will find ways to protect their equities.. Not crying foul like a bunch of old fools...
looks like you guys are praising outdated articles, very old videos, irrelevance publications as the official source of news .. I like to be on the other side of your trades... LMAO..
this video was over 10 yrs old, is it your secret weapon to use on the down days ?
This is NOT 2000's anymore, WS manipulating stock by HFT algos.. everything is automated now.. not manually done by the way Cramer and his Goldman Sach traders were doing back then..
In order for them to manipulating stock down, don't you think they have to drive it up first ? what do you call when CLDX stock goes from $12 to $32 ? I know you would claim " it was the science ".... LMAO