Yes I particularly liked Dr Pierce making the point the interim data on the combination trial will be released soon and it will also be used in discussions with the FDA in constructing the registration trial requirements, and not needing to wait for the final readout of the combination trial later next year. Very bullish hint that what they see so far is very good.
Sentiment: Strong Buy
I'm having a hard time figuring out why after releasing what to me is very solid positive results, at least doubling the typical response rate to pembrolizumab we aren't seeing a continuation of the immediate strong up trend right after it was revealed.
I looked at the presentation on the company site but didn't see a link to the oral.
Can you give me it. Thanks
I know this has been under way for about a year "A prospective clinical trial combining IT-pIL12-EP and pembrolizumab in advanced melanoma is ongoing at the University of California San Francisco" however under Oncose on the ClinicalTrials.gov site I don't see it.
Is "prospective" the word that qualifies it as not a full blown trial that meets the criteria of "ClinicalTrial"?
Per the 8-K he will receive $30,000 per month (yikes) for 12 months minimum even if terminated for cause or no cause. So $360K for strategic advice. In addition his share options continue to accrue.
Seems a bit much unless he is seriously adding value to the company.
Mix this news which I classify as a negative with the abstract of the upcoming oral presentation at AACR which I see as a positive and what do we see for a share closing price for Monday?
The AACR abstract looks very good and being given an oral presentation slot is usually because the news is both positive and potentially has significant impact in the cancer involved.
Your point about chronic neuroinflammation as the driver of AD reminds me of an article I read many years that at a facility for AD patients there were a number that did not progress at the rate typically seen. They looked at all the various factors that could explain it and found that those patients tended to have other conditions such as arthritis that required rather large doses of aspirin daily! Since aspirin is an anti-inflammatory could this be supportive of your theory. After reading this article I opted for a daily 325 mg aspirin instead of the 80 mg since although not much maybe some help. My father died from AD and maybe that could help me avoid it.