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The Blackstone Group L.P. Message Board

sam_0534 218 posts  |  Last Activity: 19 hours ago Member since: Feb 8, 1998
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    Intellipharmaceutics Augments its Rexista™ Oxycodone Development Program with Novel Overdose Deterrence Technology

    Toronto, Ontario, August 28th, 2014 – Intellipharmaceutics International Inc. (NASDAQ:IPCI) (TSX:I), a pharmaceutical company specializing in the research, development and manufacture of novel and generic controlled-release and targeted-release oral solid dosage drugs, today announced an enhancement of its Rexista™ abuse-deterrence technologies with a significant improvement designed to prevent overdose when more pills than prescribed are swallowed intact. Intellipharmaceutics’ new platform technology is branded PODRAS™ (Paradoxical OverDose Resistance Activating System).

    The PODRAS™ platform technology is covered by patents pending with the U.S. Patent and Trademark office.

    “We believe this significant advance in our abuse deterrence technology has the potential to positively differentiate Rexista™ from other abuse-deterrent technologies of which we are aware, and represents an important step towards helping patients manage their pain safely,” said Dr. Isa Odidi, Chief Executive Officer of Intellipharmaceutics. “In addition to its use with oxycodone, the new technology is potentially applicable to a wide range of drug products that are intentionally or inadvertently abused and cause harm by overdose to those who ingest them.”

    Intellipharmaceutics’ most advanced application of the PODRAS™ platform to date is to its Rexista™ product candidate (oxycodone hydrochloride extended-release tablet), which is designed to deter abuse by both physical interference and overdose.

    Preclinical studies of Rexista™ suggest that, unlike other third-party abuse-deterrent oxycodone products, if more tablets than prescribed are deliberately or inadvertently swallowed, the amount of drug active released over 24 hours may be substantially less than expected, even possibly approaching zero. However, if the prescribed number of pills is swallowed, the drug release should be as expected.

    In January 2013, the United States Food and Drug Administration (“FDA”) published a paper titled, Guidance for Industry: Abuse-Deterrent Opioids — Evaluation and Labeling, which cited the need for more efficacious abuse deterrence-technology.

    In this draft Guidance, the FDA stated, “Opioid analgesics are often manipulated for purposes of abuse. Most abuse-deterrent technologies developed to date are designed to make product manipulation more difficult or to make abuse of the manipulated product less attractive or rewarding. However, these technologies have not yet proven successful at deterring the most common form of abuse – swallowing a number of intact pills or tablets to achieve a feeling of euphoria.”

    Dr. Ed Sellers, an internationally recognized clinical pharmacologist and Professor Emeritus, University of Toronto, and President of DL Global Partners commented "The risk of overdose due to taking more opiate analgesic than prescribed is a real one. The lack of delivery technologies to reduce that risk is an unmet public health need. The announced technology is promising. Confirmation of its clinical importance in human clinical studies would be a significant contribution to deterring abuse.”

    Intellipharmaceutics currently expects to begin a series of clinical trials in Canada and the United States in the coming months to further evaluate Rexista™ incorporating its PODRAS™ platform.

    There can be no assurance as to whether or when the FDA will approve any Intellipharmaceutics' Rexista™ oxycodone application.

    Sentiment: Strong Buy

  • Blackstone Planning NYC Tower Sale for More Than $2 Billion, Near Record for U.S. Skyscraper

    Sentiment: Strong Buy

  • Reply to

    Will break out soon :)

    by sam_0534 Aug 27, 2014 12:30 PM
    sam_0534 sam_0534 Aug 27, 2014 1:44 PM Flag

    BX is a world wide investor.. great company.. great now those who are looking

    Sentiment: Strong Buy

  • Top Expectations
    DOW JONES & COMPANY, INC. 4:37 AM ET 8/27/2014
    Symbol Last Price Change
    BX 32.82down -0.28 (-0.85%)
    QUOTES AS OF 11:14:02 AM ET 08/27/2014

    Michaels Cos.'s fiscal second-quarter sales increased more than expected in the arts-and-crafts retailer's first earnings report since it went public again at the end of June.

    Shares of Michaels rose 5.7% in premarket trading as the company's full-year guidance also exceeded analysts' views.

    Michaels said it posted sales growth at existing locations of 3.2% in the period, up from a decline of 1.2% a year ago.

    "We are very pleased to build on our solid start to fiscal 2014 with another quarter of strong performance," Chief Executive Chuck Rubin said. "Broad-based sales strength was accompanied by healthy margins and our characteristic expense discipline, even as we invested in our strategic initiatives."

    The company offered full-year earnings guidance of $1.38 to $1.42 a share, above the $1.35 projected by analysts polled by Thomson Reuters.

    Michaels acknowledged the pending affect of its popular rainbow loom toy kit on its second-half results. The company enjoyed big-box exclusivity for the bracelet kit, driving a large spike in sales late last year, while analysts have expected the fad to die down.

    "We enter the back half of 2014 confident in our business, our outlook and our initiatives," Mr. Rubin said in a news release. "While we will be lapping the huge success of Rainbow Loom, the Michaels' team is enthusiastic, energized and aligned on our priorities to serving our customers and maximizing our sales and margin performance."

    Michaels, which had been taken private in 2006 by a Blackstone Group LP(BX)-led consortium of private-equity firms, has toiled in its battle with growing competition from smaller stores and the Internet.

    The market's reaction to Michaels's initial public offering was widely seen as tepid. The stock's debut came as retailers contend with persistent sales and traffic sluggishness as cash-conscious consumers seek bargains through online marketplaces.

    For the period ended Aug. 2, Michaels posted a loss of $48 million, or 26 cents a share, compared with a profit of $17 million, or nine cents a share, a year earlier. The most recent period included $68 million in debt-extinguishment and refinancing costs.

    Excluding one-time items, per-share earnings were 15 cents.

    Net sales rose 4.9% to $948 million.

    Analysts had projected eight cents a share in earnings and $943 million in revenue.

    Sentiment: Buy

  • sam_0534 by sam_0534 Aug 26, 2014 2:50 PM Flag

    still a lot of overhead stock to overcome....

    Sentiment: Buy

  • BX selling at 32.98 and earning 3.86 for 2014.... not including dividends.. Our day will come..if we just wait awhile.....

    Sentiment: Strong Buy

  • Reply to

    open post to potential investors here

    by meifud Aug 25, 2014 5:43 PM
    sam_0534 sam_0534 Aug 25, 2014 8:55 PM Flag

    Potential readers here..this guy has his own agenda... why does he post here if not a stockholder? shorts like to give the negative view...he has posted the message before..

    Sentiment: Buy

  • Reply to

    Dilution question

    by foxhsmart Aug 19, 2014 10:45 AM
    sam_0534 sam_0534 Aug 25, 2014 1:56 PM Flag

    I do not trust the managment.. just greedy guys...I bought some on 15 August but will look to see..just curioous about the Sept CC.....I was in SNH before and the just kept selling stock to increase their fees...

    Sentiment: Hold

  • sam_0534 sam_0534 Aug 25, 2014 10:57 AM Flag

    It does test ones patience...but as has been said,the longer the base , the bigger the move...stocastics as expected is oversold.. oveall chat is good.. no need to panic :)....

    Sentiment: Strong Buy

  • Reply to

    whole system collapse of markets

    by kopach Aug 24, 2014 6:16 PM
    sam_0534 sam_0534 Aug 24, 2014 9:46 PM Flag

    make it problem spending over 1 Trillion and terrible loss of life and disabled to take care of.. Mission Accomplished......I went to UVA as a state resident.. very afforable..

  • Reply to

    Possible cup and handle forming?

    by srikantmarakani Aug 21, 2014 1:38 PM
    sam_0534 sam_0534 Aug 22, 2014 7:14 PM Flag

    BX is an example of cup and handle..

  • Reply to

    Chart dosn't look to good.

    by irepoyou1 Aug 22, 2014 6:18 PM
    sam_0534 sam_0534 Aug 22, 2014 7:13 PM Flag

    looks good to me !!!! lots of support here.. cup and handle anyone ??

    Sentiment: Strong Buy

  • Blackstone Up to Strong Buy on Solid Q2 & Acquisitions
    By Zacks Equity Research
    8 minutes ago

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    On Aug 22, Zacks Investment Research upgraded The Blackstone Group L.P. (BX) to a Zacks Rank #1 (Strong Buy).

    Why the Upgrade?

    Over the past few days, Blackstone entered into a number of acquisitions. Notably, this investment manager announced a deal to acquire 50% Haynesville assets of SWEPI LP and Shell Gulf of Mexico Inc., affiliates of Royal Dutch Shell plc (RDS.A) for $1.2 billion, thus marking its foray into the energy sector. Given the ever-increasing demand for energy and expected long-term investment benefits, we believe this deal will work in the company’s favor going forward.

    Further, Blackstone is making investments in the European market, which is showing signs of recovery after a long period of sluggish growth. This could turn out to be favorable for the company in the future.

    Impressive performance fees also drove Blackstone's second-quarter 2014 results reported on Jul 17. Economic net income (ENI) of $1.15 per share outpaced the Zacks Consensus Estimate by 64%. Also, the figure was up 85% from 62 cents earned in the prior-year quarter.

    Organic growth was reflected in the quarter riding on higher revenues (up 57% year over year). Fee-earnings assets under management (AUM.TO) grew 19% from the year-ago quarter to $209.9 billion. Total AUM as of Jun 30, 2014 was $278.9 billion, up 21% year over year.

    Blackstone has been witnessing rising earnings estimates over the last 30 days with a year-to-date return of 9.5%. Further, it has now delivered positive earnings surprises in three of the last four quarters with an average beat of 42.52%.

    The Zacks Consensus Estimate for 2014 increased 3.2% to $3.84 per share, over the last 30 days. For 2015, the Zacks Consensus Estimate advanced around 1% to $3.53 per share over the same time period.

    Other Stocks to Consider

    Sentiment: Strong Buy

  • O.58 and .35 and .55 for a total of $1.48 cents......bringing it to 34.23.. so one one lost any money :) and has doubled the performance of KKR without looking at the dividend... this is the group you need to compare performance.... I have made a lot of money on BX and will comtinue to hold it..those indoubt maybe need to look for other investments...

    Sentiment: Strong Buy

  • Reply to

    bx $31 june 2007 ipo

    by sandy.criscione Aug 21, 2014 5:33 PM
    sam_0534 sam_0534 Aug 21, 2014 6:14 PM Flag

    Patience will pay off :)......

    Sentiment: Strong Buy

  • Reply to

    Something doesnt feel right

    by dugas.daniel Aug 21, 2014 3:59 PM
    sam_0534 sam_0534 Aug 21, 2014 4:25 PM Flag

    NO.. just nervous people selling into market strength.. above the 100 and 200 dma..below the 50...chart is still constructive..just a lolng it a great base to move from when it decides to move :)...

    Sentiment: Strong Buy

  • Reply to

    Possible cup and handle forming?

    by srikantmarakani Aug 21, 2014 1:38 PM
    sam_0534 sam_0534 Aug 21, 2014 3:52 PM Flag

    dont see that pattern at all.. sorry

  • sam_0534 sam_0534 Aug 20, 2014 4:15 PM Flag

    go post on FOX and your opinnionis worthless here..jerk

  • sam_0534 sam_0534 Aug 20, 2014 4:10 PM Flag

    do you know how much hell Bush caused by invading Iraq? how many USA dead and wounded...coasint over 1 Trillion dollars... bet you voted for him..jerk...

33.17+0.02(+0.06%)Sep 19 4:04 PMEDT

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