Researchers may have found a cancer cell's 'off' switch
Aside from their abnormal growth rates, cancerous cells aren't that much different from normal healthy tissue.
That's why radiation and chemo treatments can't effectively target just tumors. However, a team of researchers from the Mayo Clinic believe they've discovered a mechanism that can rein in cancer's uninhibited growth by retraining these wayward cells to die like they're supposed to.
See, when cells get old and prepare to die, they're supposed to stop dividing. This process is controlled by "biological processors" called microRNAs which feed the cell just enough of the PLEKHA7 protein to inhibit division. But in the case of cancer, the microRNAs don't deliver enough of the protein and the cells begin to divide out of control, resulting in a tumor. In a recently published study in the journal Nature Cell Biology, the Mayo Clinic team found that by injecting microRNA directly into a tumor, PLEKHA7 levels returned to normal and the cancerous cells stop reproducing.
"This is an unexpected finding," Chris Bakal, a specialist at the Institute for Cancer Research in London, told The Telegraph. "Normal cells touch each other and form junctions, then they shut down proliferation. If there is a way to turn that [process] back on, it would be a way to stop tumors from growing."
JnJ/Janssen better get this thing rolling...others with similar ideas are rushing in:
google: Researchers may have found a cancer cell's 'off' switch
interesting...thing that is great about Imetelstat is it can be used in combo with everything else, not just as THE solution...
Hi Rokky -- Damn! I'd love to go to that game...haven't been in the Stanford stadium since I lived in Santa Cruz and made the trek for a UCLA/Stanford game over twenty years ago. Unfortunately (or fortuntately) the wife, kids and I will be in Maui during that week and can't make it...otherwise I would seriously consider it!
well, technically i said your statement was a lie, not that you are a liar...but that's splitting hairs. and, i apologize. i jumped to conclusions, that you were one of those shorts who try to scare folks with stock dilution. you're right, I didn't understand the context of what you said in response to Marango. I apologize. However, I still feel insulting people to make your point is not only unnecessary but undermines your argument. explaining as you just did, goes much farther in making your point.
the reason i jumped to conclusions was your name, "yellowsumbarine," who I thought was a longtime short. i read your post with that filter in mind.
"hey idiot" ??? ...amazing how quickly some turn to insults when their assertions are challenged...perhaps they protest too much? my assertion is you are disingenuously trying to worry investors that Geron wantonly has quarterly share offerings, diluting their share price, when in fact, a shelf registration was done long ago for such occasions as demonstrated in the 10-Q and those "issuances" are already reflected in the share price.
them and everyone else. so really, your accusation is nothing.
well, that's strange and depressing. that FB page was one of the best sites for news on Geron -- aggregated information from across the web without all the troll posts. too bad it's gone. wonder what's up.
well, then your original statement is misleading. besides which, shelf registrations are already reflected in the share price.
Perhaps I don't understand issuance of stock as well as you do, but where in the above quoted paragraph does it say "new" stock? you can issue stock from stock on hand at any time without issuing "new" stock, much in the same way when you grant an employee stock options, you aren't generating "new" stock to issue to them.
this is what YOU wrote: " it issues new stock every quarter to pay for leasing corporate space, etc. Look at any SEC filing."
nor do I see "new" stock issued EVERY quarter, certainly NONE in 2015.
well, that's an outright lie. nothing subtle about it.