Was yesterday a test, a warning, a mistake, or just a sign of things to come? It sure was fun to watch unfold and I hope we see it again.....SOON!
They don't pay much and in some cases get paid for churning amongst themselves!
from Bloomberg 2014-06-17/high-speed-trading-fees-under-scrutiny-by-u-s-senators
.." Levin specifically questioned a system of incentives between exchanges and high-speed traders known in the industry as “maker-taker.” The system is the predominant way exchanges attract orders from brokers. Traders who are ready to buy or sell shares as needed, known as market makers, are paid rebates by an exchange. Traders on the other side, the “takers,” instead pay a fee.
Most stock exchanges charge about 30 cents per 100 shares to firms that trade against standing buy and sell requests. The exchanges pay less to brokers who supply them with liquidity, and profit off the difference between those fees."
You are most welcome....facts will prevail in the long run (and the stock price will take care of itself.)
Design and Characterization of a Multicellular, Three-Dimensional (3D) Tissue Model of the Human Kidney Proximal Tubule
Shelby King1, Olivia Creasey1, Sharon Presnell1 and Deborah Nguyen1
Research and Development Organovo, Inc. San Diego CA United States
Renal toxicity is a major cause of drug attrition at the clinical trial stage, and the primary site of this toxicity is within the proximal tubule. Conventional renal cell culture models lack the complexity of native tissue and thus have a limited capacity for predicting tissue-level responses. In addition, the predictive potential of pre-clinical animal trials is limited due to species-specific differences between human and animal renal functions, including differential sensitivity to insults. We designed and fabricated a human three-dimensional (3D) tissue model of the tubulointerstitial interface in which human renal interstitial tissue is supporting proximal tubule epithelial cells to facilitate their optimal morphology and function. Histological characterization demonstrated that the interstitial layer is viable and well organized, containing well-developed CD31+ endothelial cell networks. Method optimization resulted in the formation of a polarized layer of renal epithelium on top of the interstitial layer, and formation of a basement membrane between the layers. Gene expression analysis showed that the renal tissues expressed key enzymes involved in metabolism and protein processing (CYPs, renin-angiotensin system), suggesting that physiologic function is retained. These bioprinted human tissues may provide an opportunity to accurately study how compounds affect the renal proximal tubule as well as modeling pathogenic processes that involve tubular transport, cell-cell interactions, and the development of tubulointerstitial fibrosis. This work was supported with internal funds.
Moo, don't take advice from strangers (nor candy!) Seriously, from what you've posted, you don't need my advice, just time.
75,000 of those are mine and I'm not selling anytime soon (nor am I losing any sleep over the day to day gyrations.) Now back to enjoying my retirement!
looking forward to what they unveil next week at SOT ....maybe the link will reappear and be active this time!
Yes and liver tox testing is only one part of the puzzle. I always felt it was a way to fund all the other amazing potential products. We will see, I'm not going anywhere.
Well, if his mouth is moving he must be lying. But since he (she?) is on ignore it all just is a big waste of time. Best not to encourage the idiot with a response.
yes, 22 trading days for shorts to try and cover between now and then (with 28+ Days to Cover at current levels!)
from the website...........
Home » Tissues & Services » exVive3D™ Human Tissue Models & Services for Research » Download: SOT
2015 exVive3D™ Bioprinted Human Kidney Tissue Poster
Download: SOT 2015 exVive3D™ Bioprinted Human Kidney Tissue Poster
Thank you for your interest. Please use the link below to download your PDF of the poster.
I have a google news alert set so if they ever do go public I hope to get in cheap like I was able to do with ONVO.
I think it will be skin for cosmetic testing and/or individual customized breast tissue for treatment. So many exciting possibilities that I'm not concerned with the day to day as long as key milestones continues to be met or exceeded.