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Sarepta Therapeutics, Inc. Message Board

simp08801 469 posts  |  Last Activity: 12 hours ago Member since: Apr 10, 2000
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  • Reply to

    oy vey......

    by manonthemountain77 12 hours ago
    simp08801 simp08801 12 hours ago Flag

    mano

    I cannot hate a country that has graced us with hunan chicken and pork fried rice

  • simp08801 simp08801 18 hours ago Flag

    mau

    I am a mindless stock monkey

    and different people define "binary" different ways

    for example, my buddy copp appears to include bio rhythums in his definition

    but since you asked

    I do consider the impending data releases to be "binary"

    why?

    1. the information in clinical information that appears to be the exact type the FDA has been gyrating over for the the past 2 years

    2. the filing of the nda was a procedural matter, although its filing does speak to the substance of the application

    3. there can be no confusion that given the FDA's publicly displayed 2-year consternation over dystrophin, that the dystrophin related impending data will likely directly impact directly on the fda staff write up for adcom

    4. the impending data may be the last data to be released for 2015

    it got binary written all over it for me

    and IMO, the stock price will move big up or down off it, depending upon how it is perceived

  • simp08801 simp08801 20 hours ago Flag

    mano

    today is september 1

    if impending srpt clinical data to be publicly released by october 1 is good, I believe there will be fireworks here regardless of macro market

    data will inform market as to projected adcom outcome

    and IMO you have strong reason to believe that all such data is at least decent

  • Reply to

    email encryption is 90s technology

    by umntorch88 Aug 31, 2015 5:24 PM
    simp08801 simp08801 20 hours ago Flag

    dear um

    if you seriously believe zixi is "milking a dead cow", I encourage you to immediately report this to the USDA and FDA !

    and I am stopping my weekly receipt of zixmilk deliveries!

  • simp08801 simp08801 Aug 31, 2015 3:55 PM Flag

    my dear devil

    one must adapt one's views as new information emerges

    the b 4 was not available

    now it is

    it is no different that when originally said your ability to shuffle board aliases was spectacular

    based on new info, I am revising that to super duper spectacular!

  • shorts marking books

    and they got creamed on this one this month, so they are pushing here to save a tiny bit of face today

  • simp08801 simp08801 Aug 31, 2015 1:27 PM Flag

    next up, 192 week data

    using timelines for the last 3 weekly data releases as a guide, it appears the 192 week data could have been publicly released up to 37 days ago

    what would srpt do with such data and when?

    first, lets assume the data was at least decent

    what do you think the odds are that srpt would give that good data to FDA before it knew for sure that the FDA would accept the srpt nda for filing?

    I say 100%, with a margin of error of ZERO

    conversely, lets assume the data was bad

    what do you think the odds are that srpt would hide such bad data from the FDA before the FDA accepted the srpt nda for filing, only to then drop the bad data on the FDA after the FDA filed the nda?

    I say ZERO % (especially with ed kay in charge), with a margin of error of ZERO

    so at this point, it seems megla reasonable to me that the FDA had both the d recount and 192 week data prior to filing the srpt nda

    next up, the b4 data

    ...

  • I am so tired of carrying al these dumb doctors on my back, step by step, without even a single offer of a free 714 scrip

    but I digress

    I believe all who follows srpt know the impending srpt data releases on 10/1 at WMS will DIRECTLY inform srpt's future more than anything else on the horizon

    and such potential data points are b4/d recount/192 week data

    well guess what?

    I believe there is compelling reason to believe THE FD HAD ALL THOSE DATA POINTS BEFORE IT APPROVED THE SRPT NDA FOR FILING

    and I highly doubt the FDA would have filed that nda if any of SUCH data points were bad

    which means our short friends are FFFFFF'd already whether they know it not

    first up ... the d recount data

    see this May 7 quote from Srpt CEO call transcript (yes, waaay back on May 7)

    "So if you – you know I think probably the best way to frame this is typically for a confirmatory phase III trial if you are using an end point such as dystrophin and some of the things that I’ve done in the past is usually we’ll have three independent pathologist who will read the sample and then come to agreement on the data. So what was done in our 202 study is that was one site with one pathologist. And typically the FDA does not like only one person reviewing the data they want conformation by at least two other sources. So what we have done is we’ve used the same images that were read by national wide children’s hospital, but they have been mixed and blinded and then along with other samples, so we have pre and post the samples that are blinded and some of the same samples were reread, turned to 180 degrees and reread and so the three pathologist then read the samples, we looked at concordance among the read and then also looking at the basically what the outcome was. So all of that data is completed and will be presented to the FDA."

    that was May 7, over 3.5 months ago

    so what are the odds that this data was given to FDA before August 25?

    I say 100%, with a margin of error of ZERO

  • simp08801 simp08801 Aug 31, 2015 8:16 AM Flag

    dear Is

    you want to consider embracing the inner beauty of our Beloved Pearsby's posts

    you may then realize that she is a shinning light in a sea of heart wrenching and insulting postings

  • Srpt presents at WMS on October 1

    CEO publicly stated that new clinical data will be released at such presentation

    such data can include all or some of the following: b4, d recount 192 w 6mwt

    poster boards will be provided to WMS at some point

    but safe assumption is that nothing will be public until srpt issues a pr either late on September 30 or early or October 1

    that is 31 or 32 days (23 or 24 trading days), from now

    for reasons that should be obvious to all, the caliber of such data is likely more informative of srpt's future than the fda acceptance of the srpt nda

    unless of course, you drill a bit deeper and consider how long the recount and 192 data have probably been available to the company, and the related consideration of whether the FDA had at least such data when it accepted the srpt nda

    the short thesis here finally becomes 100% incomprehensible to me if the new data to be publicly released by October 1 is at least decent

    if I were short, I would be pondering what the FDA may have already seen when it accepted the srpt nda

    ...

  • simp08801 by simp08801 Aug 30, 2015 11:58 AM Flag

    Why, I have no idea

    I am just following today's trend

  • Reply to

    There is not one Drug on Planet earth

    by pearsby09 Aug 28, 2015 4:29 PM
    simp08801 simp08801 Aug 28, 2015 4:52 PM Flag

    my dear pear

    714s have zero side effects

    I have been in a 42 year trial and so far so good

  • Reply to

    Someone is bailing on this stock....

    by s.eranger Aug 26, 2015 11:52 AM
    simp08801 simp08801 Aug 28, 2015 4:50 PM Flag

    no, insiders

    robertson filed a form 4 today and just sold another 80,000 shares

    all the spur loyalists are selling

  • Reply to

    Sold my shares a few minutes ago. Good luck all!

    by simp0801 Aug 28, 2015 1:25 PM
    simp08801 simp08801 Aug 28, 2015 2:05 PM Flag

    you are so wrong

    all the dumb doctors care, deeply

  • Reply to

    Sold my shares a few minutes ago. Good luck all!

    by simp0801 Aug 28, 2015 1:25 PM
    simp08801 simp08801 Aug 28, 2015 2:04 PM Flag

    its worse than you know

    I sold all your shares too

  • Reply to

    Sold my shares a few minutes ago. Good luck all!

    by simp0801 Aug 28, 2015 1:25 PM
    simp08801 simp08801 Aug 28, 2015 2:03 PM Flag

    johnny87778

    you know better

    think about this

    what are the chances the fda had certain additional data when it determined to accept the nda?

    I think we have a BIG winner here

  • I come on this message board this am, seeking to learn about the inner zen of dystrophin, and what do I find instead?

    a series of nonsense posts about nonsense quotes

    I have reviewed the Yahoo TOS and consulted with my lawyer and I believe I have a solid case for intentional infliction of emotional distress, with malice aforethought

    RU, I particularly feel misled, if not, betrayed, by you

  • rather, it appears quite safe!

    signed, pear08801

  • simp08801 by simp08801 Aug 27, 2015 12:43 PM Flag

    today's trading so far fosters my belief that yesterday's front end was MMs unloading stock they had accumulated

    I would explain why further, but I am too hurt to type any more over the attacking posts aimed at pear today

    I am not ashamed to admit it has made me cry

  • simp08801 simp08801 Aug 27, 2015 8:23 AM Flag

    db

    the thouht that there is no real net short is ridiculous and mathematically provable

    but why interject reality into the discussion?

    I mean after all, there we no net shorts on 10/2/12 either ...

SRPT
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