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slegermark 521 posts  |  Last Activity: 14 hours ago Member since: Jan 1, 2012
  • Reply to

    Zogenix Reports Granting of Inducement Awards

    by kennebunkm Mar 5, 2014 8:45 AM
    slegermark slegermark Mar 5, 2014 9:06 AM Flag

    It looks to be an effectivly fair system. Only 900k shares to incentivize a billion+ in sales over the next three years is good use of capital.

  • Reply to

    Looking for advice

    by pillicotheguy Mar 4, 2014 2:16 PM
    slegermark slegermark Mar 4, 2014 4:06 PM Flag

    Trade common shares for a while before you get into options, and if you do options, go significantly in-the-money on a dip.
    Naw stay away from options until you feel more confident.
    Twosmallgems gave reasonable ideas.
    Pharmaceutical issues can be tricky. Zog is less speculative than others.

  • Reply to

    Comments about appeal arguments on Monday.

    by willie7 Mar 4, 2014 12:59 PM
    slegermark slegermark Mar 4, 2014 1:10 PM Flag

    spambot on the loose

  • Reply to

    down on 1,900 scared shares

    by daddylonglegs6075 Mar 3, 2014 8:39 AM
    slegermark slegermark Mar 4, 2014 12:34 PM Flag

    He's got a job interview today in Ukraine.
    He should do well there.

  • Reply to

    down on 1,900 scared shares

    by daddylonglegs6075 Mar 3, 2014 8:39 AM
    slegermark slegermark Mar 4, 2014 12:16 PM Flag

    Are you going to change your name to "Daddylongtrader"?

  • slegermark slegermark Mar 4, 2014 10:16 AM Flag

    someone here said that someone else here said it is going to zero.
    You're right, they should hold their short position until then.

  • Reply to

    Are we ready to PARTY ???

    by daggidoodle Mar 4, 2014 9:43 AM
    slegermark slegermark Mar 4, 2014 10:03 AM Flag

    nice little bonus opportunity by the shorts yesterday in the low 4's. They will have to cover the shares they shorted to me in the high 6's

  • Reply to

    It's kinda funny....

    by soulec Mar 3, 2014 9:59 AM
    slegermark slegermark Mar 3, 2014 9:57 PM Flag

    Nope, still posting to prove his tenacious stupidity.

  • Reply to

    Huge support

    by firecaptain9 Mar 3, 2014 3:11 PM
    slegermark slegermark Mar 3, 2014 9:55 PM Flag

    Accumulation is a short killer. Cover here and short higher. I don't mind as long as the march upward is steady.

  • Reply to

    any chart people ?

    by ryan1982boy Mar 3, 2014 4:38 PM
    slegermark slegermark Mar 3, 2014 9:40 PM Flag

    One doesn't hear the word colloquy in .....
    those that trade biotech tend to be higher in literacy.

  • Reply to

    Worth the read..

    by ogvek Mar 3, 2014 8:59 PM
    slegermark slegermark Mar 3, 2014 9:12 PM Flag

    Screw abuse deterancy. It compromises efficacy and it is useless pharmacologically speaking. Quite useful, politically speaking however.
    Puritanical morons.

  • Reply to

    Worth the read..

    by ogvek Mar 3, 2014 8:59 PM
    slegermark slegermark Mar 3, 2014 9:06 PM Flag

    Changing the formulation in which a chemical compound is placed, will have no effect on the potency of that chemical compound. It’s a trick question like – which weighs more, a pound of feathers or a pound of gold? Sure, different formulations will have an effect on how long it takes for the drug to enter the blood stream, how long until you get the desired effect, and even alter how the drug is released from the formulation. But potency will always remain the same because…


    Now that we know all hydrocodone products are equal in potency, we can move onto the real issue with Zohydro – the lack of abuse deterrence. Whatever the reasons, Zohydro is not in an abuse deterrent formulation and that is a real issue at hand. This is an area that groups such as PROMPT and PROP are likely in agreement because there is a real potential for abuse since hydrocodone can be crushed, affording abusers the opportunity to have a large milligram quantity in a small pile of powder for snorting…this is the very reason that OxyContin 160mg tablets were removed from the market. It is also the reason why, after OxyContin was reformulated, the IR form of oxycodone 30mg became more highly desirable on the street.

    More perspective and potential advantages of Zohydro:

    Hydrocodone, milligram for milligram is equipotent to oral morphine. It falls within the most popular of opioid classes, the phenanthrenes. Drilling down a bit, it specifically is a dehydroxylated phenanthrene. From a therapeutic standpoint, it is important to have a sizeable armamentarium of opioids from which to choose. The reasons for this are many; there are inherent biological and polymorphic patient variables, including opioid receptor differences that affect response; some patients are able to tolerate certain chemical classes and not others, and the pharmacological differences make certain opioids more or less effective for some kinds of pain (i.e. neuro

  • Reply to

    Worth the read..

    by ogvek Mar 3, 2014 8:59 PM
    slegermark slegermark Mar 3, 2014 9:05 PM Flag

    In a recent survey of pharmacy students, 100% of those surveyed responded with “no” when asked “is the hydrocodone in Zohydro more potent than the hydrocodone in Vicodin?” That same question was posed to medical doctors at an informal meeting, just days ago, where all agreed that the hydrocodone in Zohydro is identical in potency to the hydrocodone in Vicodin.


    Even Wikipedia got it right, “In the field of pharmacology, potency is a measure of drug activity expressed in terms of the amount required to produce an effect of given intensity.”

    The amount of drug in a single tablet has nothing to do with potency.

    Then why do medical people quoted in the media keep getting it wrong? Is it because the media asks the question to several people until they here the answer they want, or is because neither one knows the correct answer? Or are they using misinformation and scare tactics to sell stories? It’s probably a bit of each. Nevertheless, it doesn’t change the fact that…


    Drilling down a bit, let’s use the example of hydromorphone (Dilaudid). Most believe that the approximate equivalence to morphine is as follows;
    Oral morphine 100mg = Oral hydromorphone 25mg
    This means that you need 4x less oral hydromorphone compared to oral morphine for the same response…

    Translation, hydromorphone is 4x more potent than morphine because you need 4x less for the same response.
    That my friends, is POTENCY.
    To remind you, it takes the same amount of HYDROCODONE to do the same thing as HYDROCODONE, because…


    Last week CNN reported on Zohydro, the soon to be marketed extended release hydrocodone. In that piece, a Dr. Stephen Anderson is quoted as saying “You’re talking about a drug that’s somewhere in the neighborhood of five times more potent than what we’re dealing with now. I’m five times more concern

  • Reply to

    any chart people ?

    by ryan1982boy Mar 3, 2014 4:38 PM
    slegermark slegermark Mar 3, 2014 9:02 PM Flag

    Look to your right at the five day chart. Down a dollar, 20%. Never thought it would ever again be bought for under 4.20

    The chart has touched its bottom asymptote. I sold a profitable position in another equity after the open this morning and put the pile of chips on The Zog common. I have more faith in the performance of The Zog, than any other issue traded.

  • Only on yahoo.
    Look at all the verbatim repeats that do not make any sense.

  • slegermark slegermark Mar 3, 2014 8:03 AM Flag

    That sounds like a sea change in policy. I read it as the gubmint promoting gulf activity. And guess who is standing by to deliver the fieldwork.

  • slegermark slegermark Feb 28, 2014 10:38 PM Flag

    you screwed up. lucky nobody takes you seriously.

  • slegermark slegermark Feb 28, 2014 10:17 PM Flag

    The stock got ahead of performance. It is way overvalued right now. That is where the market wants it though. Unless they can show that the pipeline is going to bring an extra 300mm , the fundamentals just do not support the run to 54.
    Unless it is all the Zohydro they are producing for ZGNX coming on to the balance sheet.ha

  • slegermark slegermark Feb 28, 2014 10:11 PM Flag

    SA is just a forum. While they do not have an agenda, the authors do.
    SA is still better than MF , cheat sheet, zacks , insider, barrons, The Street.. and many others, because you get as much out of the discussion as the article..
    I keep a list of the quality authors . And then read their past articles for ideas.

  • Reply to

    New Short Interest Number Out Today

    by biotradezman Feb 26, 2014 6:16 PM
    slegermark slegermark Feb 27, 2014 12:31 AM Flag

    that corresponds with shortsqueezeDOTcom which puts it at the same and 12.5% of float.
    Can you believe short interest increased going into such a bullish period?
    The same thing is happening with Synergy but over there a big institution has stepped in and sucks up all the short shares above the previously shorted positions. But the shorts have not given up they keep doing it in the face of accumulation and an extremely bullish period with data coming in from two studies with known best in class molecules.
    Mr Shorty has strong faith in the algorithms. I wonder what their liquidity ratios are.
    I hope they let me know, because they are such pals and all, when they intend to short the #$%$ out of Tesla.

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