"yahoo cut rest off. here is.
Biomechanical analysis showed that Tβ4 -treated calluses had a 41% increase in peak force to failure (p
In the Journal of Orthopedic Research, TB 4 aids healing bone fractures in a mouse study. Not that anyone cares, our our dear leader, Finkel-Tinkel , woudl be able to do anything with it. Any other tiny spoec biotech woudkl have a field day with the abstracts out on TB 4. See if yahoo allows me to paste it:
"Thymosin β4 (Tβ4 ) is a regenerative peptide that we hypothesized would promote healing of fractured bone. Mice received a bilateral fibular osteotomy and were given i.p. injections of either Tβ4 (6 mg/kg) or saline. Calluses from saline- and Tβ4 -treated mice were analyzed for: (1) biomechanical properties and (2) composition using micro-computed tomography (µCT) and histomorphometry. Biomechanical analysis showed that Tβ4 -treated calluses had a 41% increase in peak force to failure (p
I wonder if Pilgrims Pride (or their bankers) has contacted SEB. I can't see how they wouldn't, at least that's my gamble. Smithfield Foods went to the Chinese. Hillshire went to Tyson. If Pilgrims wants to stay competitive and expand distribution and products beyond chicken, the only player left of size and scope that will push PPC into those leagues to compete with Tyson…is SEB. Also of interest to PPC would be the 49% stake SEB owns of Butterball Turkey. If they bought SEB's pork division (2nd largest in US)…….AND they bought SEB's stake in butterball……they woudl get a dominant stake in pork and turkey…on top of their PPC chicken. Actually, I think SEB pork division and Butterball, make far more logical business sense for PPC to buy, than Hillshire did. So will PPC contact Bresky? Will Bresky take the call? Woudl he sell out at 12-15 x EBIDTA? Would he sell his stake in Butterball with it? IS Bresky still buying back stock in open market? I've bought a few more shares. If anything were to happen, I would guess it woudl within the next 4 months or so. Plenty of time for a banker to do due diligence, and for Bresky to ask top price. I hope he takes the call, I hope he sells.
SO tell me your oinion instead of cryptic #$%$. Supposedly RGRX syas there coudl be three eye trials in early 2015 (Korea, China and US). No partner has surfaced anywhere..so I don't think that's likely. Ad I've said the only unknown is what Henry Ford is doing. I don't understand why they did a bucn of years of TB 4 neuro, only to then stop. Buty then henry Ford comes out with heart and TB 4 work. But all this was just in mice. Dr. Chopp has ties to JNJ. So I think the only possible good unknown is if Henry Ford announces some kind of neuro or heart test….done there (physician sponsored)…..not a full large phase 2, just a small one to see. Beyond that…..the eye trials mentioned won't have results till mid 2015.assuming it starts on time and patient sign up goes fast.
So yeah..trade stuff elsewhere for a while. But we coudl pop a bit if Henry Ford announces they do a test. but who knows.
until we see some of that volume actually trade, you don't know if it is a MM spooking the market with a large short offering, or if it is just someone else who is very long and wants out. Trade stuff elsewhere for next handful months . We may have a few new trials coming but they won't start for 6 months it seems. A long wait of nothingness.
The MM's don't have to cover any shorts. IMO? they'd rather just stay short side, because they believe RGRX is a POS penny stock on it's way to BK. The MM's use a MM exemption. they don't have to borrow shares or report their short to SEC. they only report dialy to FINRA.
false innuendo B7….I never bought at $3. but I do have some low $2's. But not that much. you're wrong. My low buy was 0.15…I admit to not getting any 0.05 cent share area. But I did get a lot around .15 to .18….and my basis is now around 0.55 cents. Still I'm not happy at that.
It appears to be a long seller on the large offer. That cannot be called manipulation by a MM…it's simply someone who wants to sell..unless the FINRA short dailies tell us otherwise.
Seller can't be Koreans either, as they own over 10% of RGRX and they have to file any buy or sell within 3 business days. It isn't Cavazza selling either. they own over 10% also.
No sense wringing your hands. Three possible eye trials won't start until very early 2015. the only wild card I see out there is if Henry Ford announces they are doing a small trial in heart or neuro. I don't see anythong else on the horizon….so it's pretty much dead money. Go trade other stuff for a while.
No silly. I ask questions. I find that Dr. Chopp has had personal compensation from JNJ. Thats great news. I said so. it means JNJ thinks enough of dr. Chopp to fund him sometimes……so anyone with 1/2 a brain would then try to logic it out…..just as I posted before. Dr. Chopp has ties to JNJ. JNJ has paid him before. Chopp has worked for almost 5 years with TB 4. His work pre clinical shows good result. JNJ neeeds drus. JNJ has plenty of money to spend.
It is a question we need answered. Why does henry Ford just fall away after they publish a TB 4 pre clinical abstract? why bother to do it if it isn't going to lead to a phase 1 or 2? And next logical question is, why hasn't JNJ showed interest in any TB 4 heart or neuro from dr. Chopps work?.who they have paid before for his work.
Instead of bashing me as "classic ssno"……why don't you draw teh picture of Chopp, Henry Ford and his ties to JNJ…..and give us a thought…. instead of bash.
I can't see any pharma deal brewing. There's over 800 research abstracts on TB 4..and no one gives a damn. And Finkel Tinkel is incapable. Dr. Chopp at Henry Ford is highly respected….so much so that JNJ has him in for "personal compensation". So JNJ seems to like to fund him, so they are aware of what work he does. JNJ has more money than God..JNJ is realy hungry for any new possible drug therapy…so if dr. Chopp has 3-5 years of TB 4 study.and all his studies came out positive…..and he has ties to JNJ….and JNJ needs drugs..and JNJ has $$$$….then what's missing? A couple million to license TB 4 and a couple million to do a neuro related trial, or heart.. If the phse 2 in them doesn't look good afterwards to JNJ…they drop it….a few million lost…….a crumb to JNJ..
So what gives at henry Ford? They do pre clinical that shows good solid result…..and they walk away after the abstract is published…it's been severeal years of JUST THAT after their first neuro abstracts on TB 4. Publish it, then walk away.. Now they seem to do same in heart research TB 4?
The lead doc doing the TB 4 work at Henry Ford is Dr. Michael Chopp. They have been playing with TB 4 for a bunch of years.…first in neuro, strokes and MS….and now in heart. What I'd like to know is why does Henry Ford drop off the TB 4 radar, once they finish the pre clinical mouse, rat or in-vitro stuff? Why do they bother putting a whole team on it if all they are looking for is a pre clinical abstract to get published somewhere?
MAybe there is a glint of hope? One of Dr. Chopps recent abstracts disclosed his relationships:
"Dr. Chopp has received personal compensation for activities with EVER Pharmaceutical and Johnson & Johnson. Dr. Chopp has received license fee payments from RegenRx.
See Johnson & johnson is paying Dr. Chopp? JNJ does heart and neuro stuff….so why isn't Dr. Chopp talking to JNJ? Maybe he is…….Lord knows Finkel Tinkel won't.
Anyone catch what I did? Yes, it is anothr mouse pre clinical study. but previously these had all been done in the UK with Drs. Riley and Smart…..they have done numerous ones TB 4 in heart. But the importance of the one here ( i posted it yesterday before Finkel)…is that it was not done by Smart & Riley……but by researchers at the Henry Ford Hospital. Read who else was in on it:
"The study received funding from the Henry Ford Health System and the National Institutes of Health. "
All the doctors are Henry Ford…Henry Ford put up some money….the NIH put in some money……but the key thing is that the Henry Ford researchers are able to duplicate results in TB 4 heart….that Drs. Riley and Smart have gotten…for many years of their study.
Finkel-Tinkel should be telling big pharma this. Henry Ford(with NIH money) just confirmed what Riley & Smart did. But Tinkel Finkel hasn't a clue. He might not have even done this PR, unless I beat him to it…. by telling all here frst… of the abstract.
My NEXT question is..what the "F" is Henry Ford doing? For a bunch of years they have had almost 6 researchers doing TB 4 in neuro and MS. Now Henry Ford puts about 5 new researchers on TB 4 Heart. So what the F are they doing this work, time, effort and money……if they just stop at pre clinical work? WHAT GOOD IS IT? Why is Henry Ford here? RGRX is incapable…..and Henry Ford seems only to love pre clinical…….but then they just dissappear - after the publish abstracts. Crazy.
B 7..your theory falls apart. Not a single share of RGRX was shorted today. The appox 27,000 traded were ALL long sellers. So what you have to accept is that there is a long seller out there..…close by…..they may show only 5 or 10k shares….and you pray that when that is taken out…they are "clean" and gone… and RGRX will soon rise. But there is no rule that a smart long seller has to "advertise" all the shares he has for sale. A smart seller would never show that…which is what happened today. Long seller. No market maker conspiracy short seller.
On other hand? 20,000 warants traded. Of that10,000 wre an openong short position..10k was long.
2 new TB 4 abstracts put on Pubmed..both published in journals. First was TB 4 in healing wounds….second, was another TB 4 in repair after a heart attack. But both just in mice study. No company seems to care..probably close to 800 scientific pre clinical abstracts have been done…..showing good results..over many years, from many places……….Finkel Tinkel just can't do anything with it, to gain pharma interest. Other tiny spec bios woudl have a field day with such data.year after year.Nothing comes.
you have to wait till the FINRA trade stats for today before you cry foul and conspiracy. If FINRA reports that almost all volume today was SHORT… opening….then your point valid. If FINRA shows that the 20,000 was not short, but a LONG seller…then no "foul". If it is a long seller, it's perfectly unserstandable that they might not show all the size the have to sell, at once. Let 20k go, then show more if you have to sell. That is just wise trading, not cheating.
The ones who cheat here are the MM's (mostly NITE)…they short RGRX to cap it….and never have to report the short to SEC (just FINRA)……and if they don't report to the SEC, that tells you they are naked shorting - because MM's are exempt from SEC rules that they have to borrow stock..as long as it is in the "normal" course of "making a daily market". NITE doesn't really make a daily market……..they just keep shorting RGRX - as a POS penny stock. And they don't have to tell the SEC anything. THAT is market maker abuse. FINRA stats tell us that. But wait and see what FINRA shows for today.
Yeah, hormel moved awful fast to spend $500 for some crazy milk company It makes Hormel less attractive, when they do expensive "de-worse - ify" buyouts. So mgmt and BOD at Hormel are scared…….and seem silly. But by the same token, Mr. Bresky may also be even stupider……because if PPC ever offered him 15 times EBOTDA on our Pork division, and he refused to take it….THAT is crazy and silly.
Netlosstoo…you threw out a guess that SEB pork divisoon could do perhaps $300 million in EBIDTA in 2014. And Pilgrims pride (PPC) was willing to bid 15 times EBIDTA for Hillshire…..if PPC did same for our Pork division…..that comes out to a $4.5 BILLION offer…which woudl value pork division at about $4,100 per SEB share (pre capital gains taxes). SEB is now at about $3,060. So just the Pork division, at 15 x EBIDTA….is ALONE worth almost 35% MORE than what ALL of SEB trades for now. If Bresky did not own 77% of SEB, this stock would have been put in play immediately after Hillshire. The discout to valuation is too huge. We jjust need to know…WILL Bresky entertain any offer for pork at 15 times EBIDTA…..or will he do the wrong thing - so they keep pork so young Bresky family members work their way up in it…..just as Bresky jr. did.
No, I don't think they are trying to take SEb private. there are advantages to the Bresky family for having SEB stay as a public company…like estate and family issues. Shares of stock can be divided and distributed equally as family needs (estates) come up. I don't know how "extended" the Brasky family is, from it's founders……..but I bet there is a lot of kids, grand kids and great grand kids….who all are tied into the family holdings of SEB. But that said, it doesn't mean that Bresky family might not consider maximizing the value of the 76% stake they own. Easy to do! You don't NEED your OWN PERSONAL money……just use the several hundred milliion the books at SEB to buy back shares. Why use your own money?
The million dolar question is…WILL Bresky sell out Pork? I think the odds just increased a bit..because Hormel meats just spent close to 1/2 billion on a dumb acquisition…..you don't have to be a genius to see that the sole reason Horemel did it was to make it's finances more stretched…..with a buyout that has nothing to do with meats. If Homel pays $450 million for it……a buyer of Hormel will pay to fork out that extra $450 million….probaby by asuming the debt that Hormel took to do it.
All this makes SEB pork more attractive……..
Wow, interestiung item. Hormel Foods seems to be in a BIg rush to make expensive, non meat buyouts. They just bough a company that has nothing to do with meats, Muscle Milk? The code life and sitribution makes no sense……they are sold in differerent areas of the supermarket. Hormel must be very scared of someone that has them in theor sights. Best defense? Spens a ton to make studpid acquisition in the name of supposed "diversity"
This makes SEB's prok division even MORE desirable. Seems like Hormel would rather debt up it's Co….on silly buys, than risk being a hostile offer.:
"Hormel Foods agreed Monday to buy Muscle Milk maker CytoSport Holdings for about $450 million, a fresh move by the meat processor to expand into other retail food businesses."
Are you listening Mr. Bresky? Hormel just got LESS attractives as a buyout candidate because they waste money. SEB pork division just became more valued because it is NOT diluted .
Mr. Nresky…please dream of 15 times EBIDTA for pork? It's billions.
Here's the quandry for TB 4 in EB…and good luck to Koreans. The results are posted on clinicaltrials.gov.
There were 30 pts total. 8 of those were placebo. 22 were TB 4. Of the 22 TB 4, 5 dropped out….but they are still counted as using TB 4 even tho' they did not finish. And you can asume it did not work otherwise they wouldn't have dropped out. So TB 4 had 17 pts.
The final report stated that in placebo 5 of 8 had their EB lesions totally heal. Of the 17 getting TB 4, 8 had complete EB lesion healing. The issue the FDA will have is that in the PLACEBO arm, about 63% were healed. In the TB 4 arm TB 4 healed 36%..so 63% placebo, 36% TB 4. BUT, that 36% includes ALL 22 pts. FDA rules state that if a pt took TB 4 and drops out, the drop outs are stillcounted in TB 4 arm. I think that is very unfair. It shoudl only be counted in the 17 pts who finished TB 4 fully.
So how does one explain to the FDA that there is NO THERAPY for EB…..but an inert plecbo creme cured 63%….and TB 4 cured a goodly number too. What's the FDA to do?? A water gel won't heal EB…..so was the TB 4 mixed up with placebo? Only explanation I can get. Another screwed up RGRX trial.
Didn't read to me like they were going direct to the FDA. I don't think the FDA would do much for them. There is no treatment for EB. .especially if RGRX used an inert placebo (probably water gel) for placebo in the phs 2 we did. The problem was that the placebo gel, which can't work, otherwise all EB sufferers woudl use it…….got a good efficacy response…….the other problem is that the TB 4 also got an efficacy response. So it's one of a couple things….either a water based placebo gel is the new cure for EB..…or TB 4 is..…you can't have it both ways if both showed efficacy. That is what the FDA will tell them. But the far more likely scenario is that since it was a 6 year trial……the placebo and TB 4 got mixed up. So all patients showed efficacy. I just don't see how a water based placebo gel successfully treated EB.. The FDA hands are tied. They know placebo gel won't work, but the whole trial needs to be re-done.which won't happen because it took 6-7 years for RGRX do do it…there are no EB patients willing to do trials. None want placebo risk. You'd probably get a lot of pts if it was SOLEY a TB 4 trial.parents will try any drug as long as it's safe. But the FDA demands blinded and placebo trials.
EB is a mess for RGRX.