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spainte 43 posts  |  Last Activity: Apr 7, 2009 10:25 AM Member since: Jan 7, 1998
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  • spainte by spainte Apr 7, 2009 10:25 AM Flag

    As a holder of BEARX, what do you think is the potential impact of the continued regulation changes?

    "The moves come as the SEC meets Wednesday to discuss further potential restrictions on short sellers. These include reinstating the "uptick rule," which until 2007 had required short sellers to wait for a rise, or uptick, in a stock's price before placing their bet that it would go down."

    http://finance.yahoo.com/banking-budgeting/article/106872/Short-Sellers-Squeezed-All-Around;_ylt=Atv7jR9mvq3gEU0hQ8.M7cK7YWsA?sec=topStories&pos=9&asset=TBD&ccode=TBD

    I'm too busy at the moment to dig out the prospectus but how much of Tice's transactions would you consider to be "naked"? Would you consider BEARKX a market hedge or is there a significant speculative side of it?

    Regards..

  • Reply to

    RE:

    by A Yahoo! User Jul 18, 2006 10:06 AM
    spainte spainte Feb 9, 1999 9:19 PM Flag

    Has anyone else noticed the spikes on Thur Fri and two on Tue?
    These all look around 38K shares which is in the $ 250K range. Coincidence? Buyer or Seller?

  • Reply to

    RE:

    by A Yahoo! User Jul 18, 2006 10:06 AM
    spainte spainte Jan 29, 1999 3:40 PM Flag

    Sell concept of seeds to the patients and
    Urologists and Theraseeds to the Radiation Oncologist and
    Medical Physicists. Service and product quality are
    paramount to the latter while the former need to be
    shown/proven that there is another option. Don't forget
    selling HCFA and insurance cos. If HCFA indeed rolls this
    all into a DRG type classification and only
    reimburses some rediculously low amount, you won't find a
    competent doc to do an implant. I hope J&J and TGX have
    lobbiest working this side of the coin.

    Our Indigo
    rep came by for the first time about 3 weeks ago. One
    level of their strategy is patient brochures with our
    docs photos in them and videos for patient education.
    I think the press lately has been down on seeds and
    I don't know why. That article in the Parade
    magazine a couple Sundays ago barely mentioned
    them.

    Good luck longs, take your profits shorts, get HIV
    from sucking tainted blood you leech
    lawyers,

    long again,
    spainte

  • Reply to

    RE:

    by A Yahoo! User Jul 18, 2006 10:06 AM
    spainte spainte Jan 23, 1999 8:42 PM Flag

    I got my last email from the Big Dog. He is
    dropping his internet service. You won't see him posting
    again. Any posts are from want-to-be stray dogs from the
    pound.

    I got out at 10 on a stop loss but am watching for
    upward movement. Thanks Stock_Detective for the TA.

  • Reply to

    RE:

    by A Yahoo! User Jul 18, 2006 10:06 AM
    spainte spainte Jan 12, 1999 1:45 PM Flag

    *

  • Reply to

    RE:

    by A Yahoo! User Jul 18, 2006 10:06 AM
    spainte spainte Jan 11, 1999 2:14 PM Flag

    Added half again to my portfolio up to 20%
    (again) of my holdings. Yes, as a long I am nervous about
    this but the Indigo sales force is out of the gate.
    With the general market forcasted to be up until
    spring, this is a buying opportunity.

    I might miss
    some sleep for a while, but I was there in July and
    I'll be here for years to come. As long as surgeons
    are referring patients and they comeback smiling with
    PSA's <0.1, I'll be buying THRX.

  • Reply to

    RE:

    by A Yahoo! User Jul 18, 2006 10:06 AM
    spainte spainte Dec 23, 1998 10:40 AM Flag

    I was worried that the gap this AM would be
    filled but look at this RTQ:

    10:36
    Bid 100 16
    7/8
    Ask 1 16 15/16
    last 16 15/16

    Look out
    above!!!

    PS Thank you Yahoo for enforcing your policy.

  • I had dropped out of the thread for the last
    couple weeks since the signal to noise ratio inverted.
    This list of id's will help me cull the messages and
    read only those with intelligent comments. Sorry I
    didn't make your vote but put me down for an
    AYE.

    On the TGX front, I am back in at 17% of my
    portfolio in TGX. We also received notice at our hospital
    about the NYE recall though we haven't done any I-125
    implants in a year. I see the biggest battle for seed
    implants to be HCFA reimbursement issues. Technical fees
    are under assault by virtue of an overhaul of
    procedure coding practices.


    http://www.aamc.org/hlthcare/regs/outpps/outppspr.htm

  • Reply to

    RE:

    by A Yahoo! User Jul 18, 2006 10:06 AM
    spainte spainte Nov 20, 1998 5:05 PM Flag

    Big Mike wrote:
    Interesting to note if the
    major declines for TGX fall just before or around the
    3rd.
    Saturday of the month. I don't have a reference
    for checking it out, and trying to
    interpolate
    off a graph is not very exacting, but it appears that
    out of the last 13 months 8
    of the lows fell on
    the 3rd. or the 4th.-- 2 months were all time highs,
    2 months were
    around the second week and 1
    month was flat.
    ---
    Yahoo gives closing price
    tables under the charts (new feature). Would this help
    you analyze this "pattern"? I don't get the statement
    about "lows fell on the 3rd or the 4th" Do you mean the
    3rd/4th Saturday or the 3rd/4th day of the month? Please
    clarify your whole statement. Your observation could be
    related to options expiration.

    I'm back in today
    with more shares than ever. I had triggered a stop
    loss at 18 3/16 for half my shares. Used same $$ to
    get back in at 15 today. Nothing immoral about that
    is there? Isn't this technically the same as
    shorting against the box? I am long on the company but the
    technicals seem too easy to read to resist riding the wave.

  • Reply to

    RE:

    by A Yahoo! User Jul 18, 2006 10:06 AM
    spainte spainte Oct 29, 1998 5:47 PM Flag

    Looks like it broke and held (albeit slight)
    above 20 today. I have a stop loss a couple points
    below. I don't think it will trigger though UNLESS
    Brazil, White House, Russia, Asia, etc unravels further
    (which I am betting real $$ it will).

  • Reply to

    RE:

    by A Yahoo! User Jul 18, 2006 10:06 AM
    spainte spainte Oct 29, 1998 1:52 PM Flag

    Thanks aplepear for the summary. Here is the
    abstract as it appeared in the proceedings (IJROBP V42 N1
    Suppl pp 121).

    Proceedings of the 40th Annual
    ASTRO Meeting

    PANEL V

    CONFORMAL
    RADIATION APPROACHES TO THE TREEATMENT OF EARLY PROSTATE
    CANCER: TECHNIQUES, OUTCOMES & PITFALLS

    Steven A.
    Leibel,M.D., John Blasko, M.D., P. William McLaughlin, M.D.,
    James Purdy, Ph.D.
    Memorial Sloan-Kettering Cancer
    Center, Seattle Prostate Institute, Providence Cancer
    Center, Mallinckrodt Institute of
    Radiology

    Three-dimensional conformal photon beam radiation therapy (3D-CRT)
    and brachytherapy alone or combined with external
    beam irradiation represent two approaches to conformal
    therapy in the treatment of patients with localized
    prostate cancer. Each of these approaches has its
    proponents. Patients who are candidates for each modality are
    often in a quandary as to which treatment to choose.
    There have been no randomized comparisons between these
    two modalities and little reporting of comparative
    date by patient characteristic stratification and
    using a common definition of PSA response. In this
    panel, the technical details of 3D-CRT and brachytherapy
    will be reviewed and patient selection issues
    discussed. The biochemical outcome, acute morbidity and late
    toxicity of each modality will also be
    presented.

    Each of these approaches presents critical problems
    which remain unaddressed or unresolved. 3D-CRT
    represents a radical change in radiation oncology practice.
    Defining target volumes and organs at risk in 3D by
    drawing contours on CT images on a slice-by-slice basis,
    as opposed to drawing beam portals on a simulator
    radiograph, can be challenging. Another drawback of the
    3D-CRT approach is the significant amount of time and
    effort required for contouring the target volume and
    sensitive normal tissue structures. In addition,
    considerably more dosimetric data must be analyzed when a
    3D-CRT plan is evaluated. How large of margin to allow
    for the PTV (region to account for positional
    uncertainties has not been fully determined, and it is now
    well-documented that there can be considerable motion of the
    prostate and seminal vesicles. Clearly, incorrect margins
    for PTV will result in a geographical miss. A more
    advanced 3D-CRT approach, intensity modulated radiation
    therapy (IMRT), is now being implemented. However, IMRT
    quality assurance procedures are not well established,
    introducing a potential for error.

    For brachytherapy,
    a variety of source distributions (peripheral vs
    homogeneous) have been used without a consensus regarding
    total prescription dose, margin and urethral dose.
    Post-implant studies have consistently demonstrated the
    potential for dosimetrically significant seed placement
    error, despite ultrasound guidance. Difficulties with
    image registration (ultrasound vs CT vs MRI) and
    prostatic edema complicate post-implant dosimetry and
    evaluation. Even if accurate post-implant dosimetry were
    possible, no guidelines regarding acceptability of implants
    have emerged. It is unclear without guidelines if a
    patient should undergo a second implant procedure to
    increase minimum target dosage. Further, without
    post-implant dosimetry and guidelines, dose-response studies
    (dose escalation or de-escalation) will not be
    feasible. Potential solutions to these pitfalls of 3D-CRT
    and brachytherapy will be discussed.

  • Reply to

    RE:

    by A Yahoo! User Jul 18, 2006 10:06 AM
    spainte spainte Oct 28, 1998 10:46 PM Flag

    RE: Federal Register
    CPT codes are the numbers
    which describe specific medical services ie 77300 is
    "continuing physics" (I think I got the right number). The
    federal register looks like an incomplete listing of CPT
    codes with their brief descriptors. The $ amounts I
    think go with a particular CPT code. Many codes are
    charged for an implant (We charge about 10 different
    codes). I really can't comment on the nature of this
    incomplete list. Maybe these are codes which are up for
    review. Why only some have $ values is beyond
    me.
    Medicare balked on reimbursing for seeds at their normal
    rate on a recent patient. This was due to the increase
    in pricing from TGX. You would think that the
    patient would then be forced to pay the difference, but
    my understanding is Medicare dictates the
    "coinsurance" that is the patients limit of responsibility.
    (Please correct me if I have this wrong) Our docs got it
    straight with medicare and wrote a letter to TGX. This is
    again an area where TGX dropped the ball. They had not
    informed Medicare or their price increase so Medicare was
    reluctant to honor our reimbursement request.

    I read
    the abstract on the Panel discussion in the "Red
    Journal". I will try to retype it for all tomorrow. There
    wasn't any indication that outcomes of surgery vs brachy
    were on the agenda of that particular segment of the
    meeting. I would love to hear from an attendee about this
    panel so pipe in if you were
    there.

    ENFP-Extroversion:Intuition:Feeling:Perceptive
    This is the complete opposite from PG. Myers-Briggs
    break down into four classes with two extremes. You
    score inbetween the extremes based on a battery of
    tests. I am an INTJ but pretty middle road on a couple
    categories (don't remember which ones). I really don't go
    around classifying everyone, but I know it is futile
    trying to argue with an ISTJ since they have come to a
    conclusion on their own based on "facts" without regard to
    whether their perception could be wrong and to hell with
    anyone who disagrees. (how's that for a runon
    sentence)

    Back to reimbursement. I spoke with a local medical
    director with a LARGE HMO (happens to be mine) when a
    patient was initially denied pre-approval for a seed
    implant. Their policy called it "investigational". They
    also didn't have Pd-103 listed as an isotope (only
    I-125). The medical director concurred with me that this
    must be an old policy since he remembers having
    discussions with our oncologists about the state of prostate
    brachytherapy today. We still have to file a letter to get
    prior approval but it makes me wonder how many patients
    have asked their insurance (sic) if they cover and
    implant and took NO as the final word. A minor dragon
    slain for the empire.
    (I hate managed health
    care)
    Sorry so long.

  • spainte by spainte Oct 28, 1998 5:16 PM Flag

    PG:
    You, my fellow physicist, are an asshole.
    There is a chip on your shoulder nearly the size of
    your brain.

    You are a Myers-Briggs personality
    type ISTJ to the extreme.
    Introversion:Sensing:Thinking:Judging.

    "Serious, quiet, earn success by concentration and
    thoroughness. Practical, orderly, matter-of-fact, logical,
    realistic and dependable. See to it that everything is well
    organized. Take responsibility. Make up their own minds as
    to what should be accomplished and work toward it
    steadily, regardless of protests or
    distractions"

    Just because Big Dog is an ENFP, you don't have to
    rail on him.

    I don't know what Gecko or Ralph
    are but keep posting and I'll put you guys in a
    category as well.

  • Reply to

    Spit Ball Fights When We Should Be Celeb

    by bigdogofnorthcarolin Oct 27, 1998 12:17 PM
    spainte spainte Oct 27, 1998 12:55 PM Flag

    We have broken through the 18 1/4 resistance of
    July 13th close. If we close at these levels, this
    could be a rebound to the pre-July 3rd massacre
    levels...

    Big Dog might be right (flame throwers on)

  • Reply to

    RE:

    by A Yahoo! User Jul 18, 2006 10:06 AM
    spainte spainte Oct 13, 1998 1:46 PM Flag

    Seed implants are typically an adjuvant therapy
    (along with other therapies) with hormone and/or
    external beam. Some patients have external beam alone,
    some have seeds alone, some have a combination. You
    could say they are in competition since it is often
    that the patient is offered the choice between
    external beam and seed implant or a combination. This
    competition however lends more credibility to radiation
    therapy as a whole as a healing science and therefore
    benefits both.

  • Reply to

    RE:

    by A Yahoo! User Jul 18, 2006 10:06 AM
    spainte spainte Oct 12, 1998 1:14 PM Flag

    > What is 3D-CRT?

    Three dimensional conformal radiation therapy.
    This is external beam radiation therapy where fields are shaped to "conform" to the prostate or other target volume.

  • Reply to

    RE:

    by A Yahoo! User Jul 18, 2006 10:06 AM
    spainte spainte Oct 9, 1998 1:17 PM Flag

    Thanks, Bamboo, for the article on Gonadimmune.
    It really needs to be noted that this new drug is
    primarily for ADVANCED prostate cancer. Castration is
    sometimes performed on these cases to cut off the
    testosterone (sp?) production which the ProstCA feeds on. This
    would be an alternate therapy to castration, not seed
    implants. It might be a concominant therapy for an implant
    such as hormone therapy (androgen ablation) is today.
    My long term view is that the advanced prostCA
    demographics should be shrinking while the early stage prostCA
    is growing with the wide spread use of PSA testing
    catching it at an earlier stage. Thats not to say there
    isn't a future market for such a drug as gonadimmune,
    but, I think the growth potential for such a drug will
    only be there if it is more effective with fewer
    adverse reactions than current hormone
    therapies.

    Welcome back BD. [for Bar5wen: I'm really BD posting as
    spainte to make you think I'm a different person. I
    actually am C Jacobs and I have nothing better to do while
    my company is steadily loosing money. As a matter of
    fact, there is really no such think as Pd103. We
    actually buy bulk rice from China and spray paint it
    silver with Krylon and sell it for $50+ each. Pretty
    good raquet, huh?]

    mdt81: Isn't 95 data kind of
    "old"? You are at a big center, I am at a little center.
    I know of at least a few centers within GA alone
    that are/have started up implants in the last year in
    cities with <150,000 populations. Startup costs are
    really minimal relative to other radiation therapy
    modalities. A good statistic to look at would be the
    attendance at the training courses in Seattle and Flordia
    (are there others?)

    I think the whole market
    will tank like '29 or worse before it gets better. But
    I'm still holding my shares of TGX and hedging my
    future losses with a Bear mutual fund.

  • Reply to

    RE:

    by A Yahoo! User Jul 18, 2006 10:06 AM
    spainte spainte Sep 18, 1998 5:26 PM Flag

    Thanks for the citations. I will get copies to
    add to my folder. Saw a patient today who had poor
    margins on surgery and is here for salvage external
    beam.

    I heard from bigdog today. He's is buying more...
    He has told me that he won't be posting until we see
    18.

    My take on the stock action is that as
    long as I'm buying, I like the price low, it is only
    when I am ready to sell that I would like to see a
    nice return on my money. It will be 10 more years
    before the last of the baby boomers get their 1st PSA
    test. To me that means 10 more years of pumping out Pd
    seeds for TGX to an increasing population of buyers. I
    guess you might say that I'm LONG on TGX.

  • Reply to

    NASI

    by YahooFinance May 7, 1998 3:29 AM
    spainte spainte Aug 14, 1998 5:50 PM Flag

    From NASI Quarterly 8/11/98:
    [Cutrer
    concluded, ``With increasing manufacturing capabilities now
    being linked to automated and
    semi-automated
    systems,
    expansion is more easily implemented on a modular
    basis. As a result, we do not consider NASI to be

    capacity limited for
    I-125 brachytherapy seed
    production. Additionally, we believe that the implementation
    of similar systems for
    manufacturing
    Pd-103
    brachytherapy seeds will be capable of yielding similar
    production results later this year.'' ]

    From NASI PR
    7/6/98
    [There are a number of important factors that
    could cause actual results to differ materially

    from those expressed in any forward-looking statements
    made by the company including the risk factors

    appearing in the
    company's annual report or Form 10-KSB
    for the fiscal year ended Oct. 31, 1997, the
    availability of
    adequate supplies of
    Pd-103, whether
    produced by the company or **purchased** from third party
    vendors, or other factors
    identified from time to

    time in the company's filings with the Securities and
    Exchange Commission. ] Emphasis added.

    I don't
    think TGX is going to sell Pd to NASI as long as they
    can make the margins they are demonstrating. Is

    there anyone who manufactures Pd-103 as a raw material
    that NASI is planning on processing into seeds?

    TGX could benefit from the automation processes of
    NASI (if they are truely that good) and loosing the
    one
    trick pony image by selling I-125. NASI would
    benefit by picking up a real winner of a company with all
    the
    trimmings. At stock prices like this, Ms. Jacobs
    is probably looking a all her options (refer to the
    letter
    included with the mailing of the quarterly
    statement).

    Just hypothetically, what effect would a merger
    have on the stock price of these two
    companies?

    Just something to think about this weekend.

  • Reply to

    RE:

    by A Yahoo! User Jul 18, 2006 10:06 AM
    spainte spainte Aug 14, 1998 5:36 PM Flag

    Cleo or other TA's out there, where do you think
    the bottom is?
    At prices like this, NASI may be
    making PD-103 via acquisition. A merger has been
    suggested on the NASI board. Note the following
    quotes.

    From NASI Quarterly 8/11/98:
    [Cutrer concluded,
    ``With increasing manufacturing capabilities now being
    linked to automated and semi-automated
    systems,
    expansion is more easily implemented on a modular basis. As
    a result, we do not consider NASI to be capacity
    limited for
    I-125 brachytherapy seed production.
    Additionally, we believe that the implementation of similar
    systems for manufacturing
    Pd-103 brachytherapy seeds
    will be capable of yielding similar production results
    later this year.'' ]

    From NASI PR
    7/6/98
    [There are a number of important factors that could
    cause actual results to differ materially
    from those
    expressed in any forward-looking statements made by the
    company including the risk factors appearing in
    the
    company's annual report or Form 10-KSB for the fiscal year
    ended Oct. 31, 1997, the availability of adequate
    supplies of
    Pd-103, whether produced by the company or
    **purchased** from third party vendors, or other factors
    identified from time to
    time in the company's filings
    with the Securities and Exchange Commission. ]
    Emphasis added.

    I don't think TGX is going to sell
    Pd to NASI as long as they can make the margins they
    are demonstrating. Is there anyone who manufactures
    Pd-103 as a raw material that NASI is planning on
    processing into seeds? TGX could benefit from the automation
    processes of NASI (if they are truely that good) and
    loosing the one trick pony image by selling I-125. NASI
    would benefit by picking up a real winner of a company
    with all the trimmings. At stock prices like this, Ms.
    Jacobs is probably looking a all her options (refer to
    the letter included with the mailing of the quarterly
    statement).

    Just hypothetically, what effect would a merger have
    on the stock price of these two
    companies?

    Just something to think about this weekend.

    PS
    I would love to see the imposters on the yahoo
    boards get what they deserve, a big short squeeze to new
    highs.

KO
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