Recent

% | $
Quotes you view appear here for quick access.

Isis Pharmaceuticals, Inc. Message Board

stockmktgenius 1270 posts  |  Last Activity: Aug 18, 2015 5:30 AM Member since: Oct 12, 1999
SortNewest  |  Oldest  |  Highest Rated Expand all messages
  • stockmktgenius stockmktgenius Aug 18, 2015 5:30 AM Flag

    This is HUGE because once word gets out, pressure will build on the FDA to stop the test and release the drug to all SMA children. This will be wonderful for the children, and of course that should be first in our minds. When this has happened in the past with other medicine, it has been huge for the companies involved- their stock has SHOT UP. My belief is this will happen here, but if it doesn't, I believe the drug will still be approved in 2017 and will be huge then.

    Sentiment: Strong Buy

  • stockmktgenius by stockmktgenius Aug 15, 2015 12:48 AM Flag

    I haven't been on this board for some months, but see Dark, his new alias Shecky, and all the rest are still controlling this board. Their purpose, what they're paid to do, is to get you to NOT invest, or to get you to sell. I advise you to put them all on Ignore, as they have nothing to say and dialogue with them is basically impossible.

    Dark's handbook
    .

    I only come to this board every season or so just to repost this, which is the truth about dark/ prunejuice and his other aliases:

    This, I think, is the best post I ever made on this site. It tells the truth about dark and the other paid bashers who've ruined this board.

    BASHERS HANDBOOK

    Bashers' Tactics from the Bashers Handbook
    1: Remember, BASHERS NEVER BASH A BAD STOCK.
    2: BASHERS ALWAYS BRING UP OLD NEWS THAT YOU HAVE HEARD MANY TIMES.
    3: BASHERS POST MANY TIMES A DAY.
    4: BASHERS WILL LIE TO YOUR FACE.
    5: BASHERS KNOW YOU CAN'T VERIFY THEIR STATEMENTS.
    6: BASHERS PLAY ON YOUR LACK OF KNOWLEDGE.
    7: BASHERS PLAY ON YOUR LACK OF PATIENCE.
    8: BASHERS BRING THE PRICE DOWN. That is the basher's job. The truth is not important. Lies are the norm. Post continuously on the board every day. They are trying to hit the newbies visiting the board. They are trying to wear out the longs on the board. They do whatever it takes to wear the longs out.

    How to deal with Bashers?

    IGNORE THEM FOLKS...how bashers are paid:

    When you REPLY to bashers you give them an opportunity to earn 5-7 bucks. A basher will attempt to milk three to five replies per post at one to two dollars each. This way the basher spreads negative influence to as many stockholders as possible. A basher will create this discussion thread because it takes less time reading more messages than is necessary. This ultimately allows the basher more time to post and make money.
    NEVER ENGAGE A BASHER; if you do so then YOU BECOME THE BASHER,S AID! Read the news, do your own homework and make your own decisions

    Sentiment: Strong Buy

  • stockmktgenius stockmktgenius Aug 14, 2015 6:46 AM Flag

    Sorry but they wouldn't let me post more. You can google to get the rest of the article, plus 26 comments so far.

    Sentiment: Strong Buy

  • DoctoRx

    Special situations, growth at reasonable price, value, micro-cap

    Isis Pharma Stock Drops On Good News: Re-Evaluating The Bull Case

    Aug. 13, 2015 1:56 PM ET | 17 comments | About: Isis Pharmaceuticals, Inc. (ISIS), Includes: ALNY, AMGN, AZN, BIIB, CELG, GILD, GSK, JNJ, PFE, QURE, REGN, SNY, VRTX

    Disclosure: I am/we are long ISIS,BIIB,GILD,REGN, VRTX. (More
    Summary
    •Isis Pharmaceuticals is a largely development-stage biotech with many promising business attributes.
    •The stock has had large moves the past few years.
    •Recently ISIS has plunged even as substantive news flow keeps appearing that buttresses the bull, not the bear case.
    •A review of recent news, progress in quantitatively valuing the stock, and ideas about the stock's movement are presented herein.
    •The conclusion remains that ISIS appears to be attractive for growth stock investors; while risky, ISIS is not close to a bubble valuation.

    Background

    I introduced coverage of Isis Pharmaceuticals (NASDAQ:ISIS) on June 12 when the stock was $67, much higher than its current close Wednesday around $52. Yet the news has been almost unremittingly good. Apparently it was all priced in, and profit-taking toward its May 2014 lows below $24 has been in force. ISIS had tripled in about a year, and apparently it was ready to correct.

    This article assumes knowledge of the company, such as was provided in the June article. In addition, the comments thread to that article was simply amazing, for which I remain quite grateful. If you want to learn a lot about ISIS, please consider reading the comments, several of which are from people who are experts in the field.

    This article first updates the positive news since that article appeared, then begins the difficult process of valuing the stock.

    ISIS is especially difficult to value for a number of reasons. These reason

    Sentiment: Strong Buy

  • stockmktgenius by stockmktgenius May 30, 2015 10:37 PM Flag

    The ISIS Pharmaceuticals Story
    Scroll down to videos:http://paper.li/f-1403358692?edition_id=dd1ce320-0601-11e5-ac40-0cc47a0d1605&utm_campaign=paper_sub&utm_medium=email&utm_source=subscription


    The ISIS Pharmaceuticals Story
    Scroll down to videos:http://paper.li/f-1403358692?edition_id=dd1ce320-0601-11e5-ac40-0cc47a0d1605&utm_campaign=paper_sub&utm_medium=email&utm_source=subscription


    The ISIS Pharmaceuticals Story
    Scroll down to videos:http://paper.li/f-1403358692?edition_id=dd1ce320-0601-11e5-ac40-0cc47a0d1605&utm_campaign=paper_sub&utm_medium=email&utm_source=subscription

    Sentiment: Strong Buy

  • stockmktgenius stockmktgenius Dec 12, 2014 10:32 AM Flag

    Dark, you are a #$%$ loser and a bought and paid for liar.

  • Reply to

    Dark's handbook

    by stockmktgenius Dec 1, 2014 2:28 PM
    stockmktgenius stockmktgenius Dec 6, 2014 10:04 AM Flag

    If you look over dark and his aliases' latest comments, they're straight out of the Basher's Handbook!

  • stockmktgenius stockmktgenius Dec 3, 2014 9:11 PM Flag

    It's dark's job to bash Isis, and since he's got nothing new to say beyond toxic, doesn't work- the usual garbage- he throws in vicl for spice.

  • Reply to

    Dark's handbook

    by stockmktgenius Dec 1, 2014 2:28 PM
    stockmktgenius stockmktgenius Dec 3, 2014 7:44 PM Flag

    Substantial reductions of up to 86% in triglycerides observed
    All patients achieved a triglyceride level

  • Reply to

    Dark's handbook

    by stockmktgenius Dec 1, 2014 2:28 PM
    stockmktgenius stockmktgenius Dec 2, 2014 11:42 AM Flag

    According to Dark's handbook above, I should ignore nonsense posts from idiots like you, so I will, you moron.

  • stockmktgenius by stockmktgenius Dec 1, 2014 2:28 PM Flag

    I only come to this board every season or so just to repost this, which is the truth about dark/ prunejuice and his other aliases:

    This, I think, is the best post I ever made on this site. It tells the truth about dark and the other paid bashers who've ruined this board.

    BASHERS HANDBOOK

    Bashers' Tactics from the Bashers Handbook
    1: Remember, BASHERS NEVER BASH A BAD STOCK.
    2: BASHERS ALWAYS BRING UP OLD NEWS THAT YOU HAVE HEARD MANY TIMES.
    3: BASHERS POST MANY TIMES A DAY.
    4: BASHERS WILL LIE TO YOUR FACE.
    5: BASHERS KNOW YOU CAN'T VERIFY THEIR STATEMENTS.
    6: BASHERS PLAY ON YOUR LACK OF KNOWLEDGE.
    7: BASHERS PLAY ON YOUR LACK OF PATIENCE.
    8: BASHERS BRING THE PRICE DOWN. That is the basher's job. The truth is not important. Lies are the norm. Post continuously on the board every day. They are trying to hit the newbies visiting the board. They are trying to wear out the longs on the board. They do whatever it takes to wear the longs out.

    How to deal with Bashers?

    IGNORE THEM FOLKS...how bashers are paid:

    When you REPLY to bashers you give them an opportunity to earn 5-7 bucks. A basher will attempt to milk three to five replies per post at one to two dollars each. This way the basher spreads negative influence to as many stockholders as possible. A basher will create this discussion thread because it takes less time reading more messages than is necessary. This ultimately allows the basher more time to post and make money.
    NEVER ENGAGE A BASHER; if you do so then YOU BECOME THE BASHER,S AID! Read the news, do your own homework and make your own decisions. Le Less

  • stockmktgenius stockmktgenius Sep 4, 2014 6:07 AM Flag

    http://finance.yahoo.com/echarts?s=ISIS+Interactive#symbol=ISIS;range=2y

  • stockmktgenius stockmktgenius Sep 4, 2014 6:07 AM Flag

    If you click on the Isis chart, then click on 2 years, then "Compare" and fill in "VICL" that'll tell you everything you need to know about how terrible dark's advice has been. Vical investors have gotten killed while Isis investors have gotten rich. Dark is paid by people who want to buy Isis cheap, so his job is to discourage you. Big waste of time to read him or his aliases. Go to investor village if you want to read something intelligent about Isis.

  • Reply to

    Why I'm Confident

    by stockmktgenius Aug 27, 2014 11:56 PM
    stockmktgenius stockmktgenius Aug 30, 2014 8:15 AM Flag

    This past week, Prohost Biotechnology, a respected evaluator of biotech companies and their products, predicted Isis will close 2014 at $60 and 2015 at $150 a share.

    BMO Capital had the following analysis: BMO Capital analyst Jim Birchenough reiterated an Outperform rating and $70 price target on ISIS Pharmaceuticals (NASDAQ: ISIS) after the company announced the initiation of a phase 3 study evaluating ISIS-APOCIII-Rx in patients with familial chylomicronemia syndrome (FCS).

    "High unmet need, unprecedented efficacy, and absence of competition provide a clear path to potential revenues of $600mm to $1B, with full rights retained by ISIS. Following approval on KYNAMRO and broad development of antisense therapeutics across 30+ indications, we believe that antisense therapeutics have been substantially validated with significant clinical and regulatory de-risking not reflected in current discounted valuation," the analyst said.

    The firm remains buyer of the stock saying only partial value is being attributed to 3 of 30+ programs and where upside potential from programs like FCS, SMA, TTR, FXI, high-risk diabetes and other orphan, neuromuscular and, metabolic programs is being ignored.
    -------
    You guys are so smart, why waste time here with dark and his basher aliases? Come to Investor Village. The level of conversation is night and day what you find here. And while you're at it, email Jetmanbash, one of our docs there, and ask to join our private Friends of Isis board, where you won't find dark or any of his creepy make-believe friends.

    Sentiment: Strong Buy

  • stockmktgenius by stockmktgenius Aug 28, 2014 12:01 AM Flag

    This, I think, is the best post I ever made on this site. It tells the truth about dark and the other paid bashers who've ruined this board.

    BASHERS HANDBOOK

    Bashers' Tactics from the Bashers Handbook
    1: Remember, BASHERS NEVER BASH A BAD STOCK.
    2: BASHERS ALWAYS BRING UP OLD NEWS THAT YOU HAVE HEARD MANY TIMES.
    3: BASHERS POST MANY TIMES A DAY.
    4: BASHERS WILL LIE TO YOUR FACE.
    5: BASHERS KNOW YOU CAN'T VERIFY THEIR STATEMENTS.
    6: BASHERS PLAY ON YOUR LACK OF KNOWLEDGE.
    7: BASHERS PLAY ON YOUR LACK OF PATIENCE.
    8: BASHERS BRING THE PRICE DOWN. That is the basher's job. The truth is not important. Lies are the norm. Post continuously on the board every day. They are trying to hit the newbies visiting the board. They are trying to wear out the longs on the board. They do whatever it takes to wear the longs out.

    How to deal with Bashers?

    IGNORE THEM FOLKS...how bashers are paid:

    When you REPLY to bashers you give them an opportunity to earn 5-7 bucks. A basher will attempt to milk three to five replies per post at one to two dollars each. This way the basher spreads negative influence to as many stockholders as possible. A basher will create this discussion thread because it takes less time reading more messages than is necessary. This ultimately allows the basher more time to post and make money.
    NEVER ENGAGE A BASHER; if you do so then YOU BECOME THE BASHER,S AID! Read the news, do your own homework and make your own decisions. Le

    Sentiment: Strong Buy

  • stockmktgenius by stockmktgenius Aug 27, 2014 11:56 PM Flag

    I don't go to this board anymore. Dark and his various aliases have polluted it with lies and nonsense. If you want a better board try investor village, though dark is there too under then name #$%$.

    On that board, I posted the reasons I'm confident Isis will be a huge success. Thought I'd share it here with you:

    A friend who has a small investment in Isis asked me why I'm so confident. This has caused me to clarify my thinking, and here's what I came up with:

    1. They've got 33 medicines (38 by year end), any 1 of which could cause the shares to multiply. Dr. Crooke says it's like if you've got 33 shots to make a basket- pretty likely you'll succeed. Most companies have just 1 or 2 medicines. When they're suggested to me, I always turn them down as if you've got 1 or 2 chances, that's a lot less than 33.

    2. They've got $600 million cash, so they're not going broke. Most biotechs are in money trouble.

    3. They have a revolutionary technology that absolutely works and, I believe will change the face of medicine, while incidentally making us fabulously wealthy. To learn more, why don't you put in a little time at their website.

    4.They've got the best pharmaceutical companies in the world as partners: Pfizer, Glaxo, Johnson & Johnson, etc. Last week, Biogen paid Isis $18 million. They wouldn't be partners with a company that wasn't top notch. 5. Almost all shares are owned by major institutions. Fidelity, for example, has shares worth $604 million. I bet they know what they're doing.

    Sentiment: Strong Buy

  • Reply to

    BASHER'S HANDBOOK

    by stockmktgenius Jan 11, 2014 1:02 PM
    stockmktgenius stockmktgenius May 13, 2014 10:17 AM Flag

    Ain't this d truth!

  • Reply to

    BASHER'S HANDBOOK

    by stockmktgenius Jan 11, 2014 1:02 PM
    stockmktgenius stockmktgenius May 12, 2014 1:53 PM Flag

    To me this really the truth about you bashers.

  • stockmktgenius stockmktgenius May 12, 2014 1:51 PM Flag

    You and dark and NYC, all very low people who are obviously here to scare people from buying or to sell at this low price. You really should be ashamed!

  • Reply to

    BASHER'S HANDBOOK

    by stockmktgenius Jan 11, 2014 1:02 PM
    stockmktgenius stockmktgenius May 12, 2014 1:15 PM Flag

    I find this board extremely boring and abusive. There are paid bashers who post here all day every day, and someone like me who has other things to do with their life can't really compete. So I'll just post this BASHERS HANDBOOK for the hundredth time. I believe it to contain the real truth about these bashers. When u read dark or NYC or Trudy or any of the others, ask yourself why they bother? Surely it's because they're paid by people who want you to not buy or to sell cheap. That's the ultimate truth here. Then put them all on ignore, or better yet go to investor village where these people are banned.

ISIS
51.54-0.02(-0.04%)Aug 28 4:00 PMEDT