Pattern is forming. Chart technicals will drive CLDX over the next week. Company Pipeline will drive this much higher over the coming months. Bottom is somewhere between 12.06 and 12.91. Trend reversal expected after that.
ALS Breakthrough Involves Rhode Island Patient
Posted: Jun 13, 2014 9:50 AM EDT
Updated: Jun 17, 2014 9:53 AM EDT
By Mark Curtis, Anchor/Reporter - email
What you're witnessing could be major steps forward in the fight against ALS, also known as Lou Gehrig’s disease.
Kreg Palko of Barrington, is doing physical therapy on a Lokomat machine, hoping to one day walk again.
"The legs are a little tired, but over all good, though," said Kreg Palko.
Twice a week at Boston’s Spaulding Rehabilitation Hospital, Palko goes through the tedious process of being strapped in and harnessed by physical therapists, before walking with the machine for 30 minutes.
After two months of this, there is payoff.
"I can put my legs out like that, they're getting strong. My goal, you know I originally did walk into the hospital, so my goal is to walk out," Kreg Palko said.
The therapy comes after surgery at Massachusetts General Hospital, where millions of stem cells were transplanted into Palko's spinal cord, in hopes of slowing or reversing the paralyzing effects of ALS.
ABC6 Chief Political Reporter Mark Curtis said, "The procedure Kreg has undergone is not only pioneering, It is extremely rare. In fact, only about 20 people in the entire United States have had this surgery."
It was just over one year ago Palko was diagnosed with ALS.
The 49 year old former Air Force pilot is a lifelong athlete.
He played college football; was an avid surfer; and skied with his wife and kids.
"Being so active, it's a tough pill to swallow. On the other hand I am very competitive and I love a challenge, you know," Kreg Palko said.
His Rhode Island doctors say he was ideal for the stem cell surgery.
"This is big. This has applications to all sorts of things – not just ALS – but spinal cord injury and all sorts of neurodegenerative diseases. So it really is a very early step, and a very bold step, and I think it is really suitable for Kreg to be taking it," said Dr. George Sachs of the ALS Clinic at Rhode Island Hospital.
It can be an emotional roller coaster. At times Kreg laughs during physical therapy, but also shed tears talking about his wife of 22 years who stands by him all the way.
Together they've signed up for every ALS clinical trial, test, or procedure that needs volunteers.
"I hope that Kreg is going to benefit, but I know that people after us are going to benefit from this," said Elizabeth Palko, Kreg’s wife.
"Overall my spirits are good, I am happy with my progression so far," said Kreg Palko.
Kreg was even able to stand up, out of his wheelchair during our visit, knowing all the while, progress for him against ALS is just one step at a time.
"Time will tell. It's a big experiment, but right now, it's going in the right direction,” Kreg Palko said.
Again, there isn't a shelf registration listed or even planned. They are well funded through next year with $35.9 Million in cash as of the last 10-q.
See you're making my point. MIsleading by saying shelf registry. No such event has happened. You must be looking for cheap shares too. LOL. It's a bullish sign when people get desperate for shares.
The Journal of Neuroscience would be a great place to publish. Do some research. :-)
Perhaps because CUR has the only cure for ALS, or perhaps a totally new way of treating depression with NSI-189?
I'm glad to see there's some intelligent life on this board. I was starting to wonder if there was any revenant discussion or just that nonsense guy posting silly patent stuff. Anyway, I'd agree with the point above about holding off on a partner until Phase 2 results, but that's not what Garr suggested in his May interview. Obviously plans change, but given the solid data, it seems likely that discussions might be ongoing with a partner. What big Pharma's have depression drugs coming off patent in the next couple years?
I'm not so sure. Companies partner all the time, and they are allowed to look at data sets under a non-disclosure agreement before settling on terms. With the conference last week, all the data is available except for the MRI's which (if they show Hippocampus enlargement) would be of significant value in negotiating favorable partner terms. I'm just reading between the lines here. CUR wants a partner for NSI-189, and the most important piece of data is yet to be released, but all data to date is favorable.
Back in May he expressed interest in partnering NSI-189 with SmithonStocks, that was before the positive Phase 1a results were released last week. With demonstrated efficacy and data available for a partner to review, I'd expect to hear soon if a partnership is forthcoming. What type of deal might be put together? Perhaps discussions are now ongoing and that's where the MRI data is currently under consideration?
Do a search for:
"A father's gift to his daughters" and watch the CBS news piece on ALS.
That's why Neuralstem is so relevant. No other company in the world is so close to helping ALS patients - except for CUR.
Yep. Fun watching level 2. Lot of money to be made on the upside. $4 - 4.05 seems to be the sweet spot to enter. Lot of large bids going across in this range.
Russell Reconstitution complete. Let the move up continue as we ride above the 50 DMA towards $6.
Monthly Rotation Number
of Shares Value of
Change (MM) % of Shrs.
Buyers 6/27/14 13,270,877 $49.26 20.7%
Sellers 6/27/14 1,935,029 $3.92 2.5%