I expect the Phase II trial protocol to be submitted to the FDA any day now. The start of enrollment would likely occur not long thereafter, as there is no need for Provectus to wait during the 30 to 45 FDA comment period that delayed the PV-10 Phase III melanoma trial.
Nope he exercised another 185,000 at 1.02 per share.... Then they mention that they moved x amount of shares from taxable account to 401K... He still exercised another 185,000 options
Just came out
As we prepare to begin our phase 3 clinical trial for intralesional PV-10 as a treatment for melanoma and as we discuss with Chinese interests licensing PV-10 for other indications,
getting closer.... PC
Robert Andtbacka of the University of Utah discusses plans for a phase 3 trial involving PV-10 in patients
Thanks much for the email and question. I did deal with this topic in our Q3 conference call and 10-Q for Q3 (November 6th). This revenue generation hinges on regional license transactions and co-development partnerships. Both of those hinge on clinical development (as in phase 3 melanoma commencing, liver 1b/2, PH-10 MOA, combo 1b/2). Of course, these are all in process of being fully underway, so revenue generation is potentially near term.
We’ll update this topic further in planned conference call this quarter which we’ll announce publicly.
Thanks again, Pete
Pete: Being written now.
Alan: Is this including the survival data for the people in the initial Phase I?
Pete: Yes, includes years of survival data.
HCC survival in the years not 6 months... Just saying
At least you know it will work on you.... You better call Boss Dees and thank him.....
Cancer treated with Rose Bengal.
At the start of Dec. 2009 a 13 year old heeler cross, Scobie was brought to East West Vets Bentleigh with a malignant looking cancer sticking out from the inner left hind foot (in tarsophalanged region).
Scobie's tumour.The visible tumour was 5cm x 3 ½ cm. It had broken through the skin and was seated deep in around the 3rd and 4th digits.
Scobie’s owner was a philosophical, positive guy who was looking for an option to leg amputation, as no local surgical procedure would have been possible.
He and I decided on Rose Bengal injections as our most appropriate alternative to surgical intervention. I injected as thoroughly as I could on the 14th of December 2009 around bones and in between ligaments.
A second injection was done a week later as most of the tumour had died but a walnut sized bit had not. The anaesthetic required is light and short –an advantage for older dogs.
Then I went on holidays leaving a horrible looking crater in the foot for my locum to deal with.
The first picture shows the horrible gaping wound which was left after the tumour fell out of it.
Scobie's healed wound.By the 4th January the wound was granulating up and was healing beautifully.
Scobie was started on ginko biloba, cool ginseng, quercetin and rutin, PauDarco and a multivitamin supplement.These herbs were chosen by radionic hair analysis.
It is only mid May but this tumour was so aggressive that we see the current apparent resolution of this tumour as a success- for however long it lasts. Scobie is experiencing excellent energy levels so we have a very happy dog and owner.
Dr Ann Nevill
Rose Bengal and Malignant Melanoma.
The malignant melanoma can be seen in Hank's mouth.
Hank had his malignant melanoma treated in January 2013 with Rose Bengal.
He has remained well for 20 months before a recurrence has occurred.
Melanomas of the mouth are highly aggressive malignant tumours, and this result of 20 months healthy life, is very satisfactory.
We are hoping for a similar outcome from our second treatment of this tumour.
Rose Bengal prevents amputation.
Chip was a happy 10 year old robust Labrador who came to East West Vets Bentleigh in May 2012 where he was diagnosed with a 5cm Diam malignant tumour on his medial left hock. He had had a needle aspirate at his own vet who diagnosed the tumour as malignant and had recommended the limb be amputated.
After discussion with Chip’s owner we decided on Rose Bengal surgery. This involves debulking the tumour without removing extra surrounding tissue and then infiltrating that surrounding tissue with the dye, Rose Bengal.
This infiltration has an excellent success rate at removing spreading cells but some of the normal cells will also die and the wound will look pretty ugly for a week or two.
Chip was a bit over assiduous in his attention to his wound and thought he would help by removing the sliding skin graft over the 10 cm x 8 cm open area.
The wound consequently took over a month to heal but the outcome was excellent and again the owners were very happy.