Sarepta is ignored, seemingly on purpose.
None if what occurred with Eteplirsen or what is occurring with the Ebola drug makes any sense whatsoever.
The Ebola drug has to be the most tested therapeutic - tested on humans for safety and monkeys for efficacy.
Has any other Ebola drug been tested to this extent? Since the company received the $200m contract in 2010, something after that time must have created this bad blood.
In the mean time, kids with DMD will continue to suffer as the FDA puts SRPT through the third-degree, while a promising drug to treat Ebola gathers dust on a shelf.
Someone should investigate government ties to Wall st.. as I smell a rat.
AVI's first big break came in 2004, in a scary situation that sounds like it could have been its own movie plot. At a high-security facility at Fort Detrick, Md., a researcher accidentally stuck herself with a needle containing Ebola virus — an often-fatal hemorrhagic fever — while injecting mice, according to an account in The New Yorker earlier this year.
An AVI scientist who was enlisted to help quickly designed a compound, and chemists worked around the clock to create it. The drug used a mechanism known as "antisense," which uses a mirror image of the viral gene sequence — the "sense" strand — to interlock with it like a zipper, stopping it from replicating.
Five days later, the anti-Ebola drug was ready. The Food and Drug Administration (FDA) gave provisional emergency approval for its use, and the president of AVI flew to Maryland with vials.
In the end, the researcher didn't contract Ebola and didn't need the drug. But the military liked what it had seen. In a series of challenges thrown at it by the Defense Department, the company showed it could identify the "hot zones" of bacterial or viral gene sequences, and, using its interlocking technique, quickly design and manufacture a drug to stop the pathogen.
In formal Defense exercises, AVI produced drugs for H1N1 (swine) flu in seven days; for Dengue fever in 11; and for two unknown pathogens — one viral and one bacterial — in 18 days.
Simp.... institutional and BOT shorts #$%$ Sarepta. Picture a blow-up doll in prison - it gets treated with more respect than Sarepta.
“High beta, small cap biotechnology stocks have suffered disproportionate declines over the past few months, and are creating very attractive entry points for long-term investors. We would recommend buying Sarepta at current levels as we continue to believe that eteplirsen is biologically active and SRPT’s PMO-platform is best-in-class.”
It was. The shorts knew it - let's state more clearly - the shorts that control the stock knew it. It was their mission to deflate SRPT longs just BEFORE and AFTER the WM meeting.
Wall St is dictated by psychology and this is what the shorts employ to deflate significant events. The data IMHO was superb.
ask yourself this question - Did they break your will?
Braintree is 20 mins from Cambridge... c'mon Sarepta get some "ebola" killing pmo's over there!!!
IMHO, SRPT had the most advanced and tested Ebola drug.. and it's still on shelves as people die.
Eteplirsen... does any other drug offer DMD patients better hope? Still mired in FDA mud., as kids degenerate and die.
I am beginning to think there is a conspiracy of some sorts going on.. never mind that a "short bot" drops the price on the stock after every run-up.
I think it might be the only drug in supply.
CG needs to deliver.. I am not waiting "10 years".. already been here "15". Kids with DMD need Eteplirsen and all of the other exons ASAP. How long have we been harping on this? Partner if need be to do this development in parallel.
SRPT (aka "AVII") created there Ebola drug in about one week.... speaks VOLUMES about the platform, it's flexibility, effectiveness and application.
SRPT has an Ebola drug that should be in mass production.
SRPT has a DMD drug that should have been approved last year.
People are suffering.
People are dying.
SRPT's drug for these diseases is farther along than any other drug.
As obvious as a zit on the tip of your nose.
I will say this... this black box or "boxes" seems to have the capital.