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Inergy, L.P. Message Board

wilderguide 4390 posts  |  Last Activity: 10 hours ago Member since: Jan 13, 2011
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  • Reply to

    EMA opinion timeline

    by wilderguide 16 hours ago
    wilderguide wilderguide 10 hours ago Flag

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    Franca, I always figured that the highlights could be updated after the minutes were published; after proprietary right to press release had been recognized; after proper discretion had been exercised.
    Unless I"m mistaken...and minutes are due publication this coming week.
    Doesn't EMA carry an internal mandate for proprietary discretion?

  • Reply to

    google "dr.vinmantoo"

    by joeflow77 13 hours ago
    wilderguide wilderguide 11 hours ago Flag

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    The theatrics of anonymity lends itself to cruelly misleading antics. I've dealt out more than my fair share of grief to others in the name of humor, though I'm not cruel by nature. Regarding Dr Vin, I'm reasonably confident he didn't retrieve his MD out a box of Crackerjacks...nor did it come in the bag with his Happy Meal from Mickey D's. Despite his poor spelling, laughable grammar, and inept sentence structure, I believe he is a competent academic with a wealth of knowledge and experience to share...if only he could convince others that he's smart; that his life is every bit as great as he says it is...anonymously...on a Yahoo Message Board.
    Did I say I was "reasonably confident" in Dr. Vin's academic capacity...???
    I meant "darned confident'.. Us illiterate rednecks know the "real deal" when we see it...
    I'm tellin' ya...he's as real as the rain.Real as rabid ringworm on the rampage. Real as a raped rooster.
    Really...

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    Cabo was included on last week's CHMP agenda for consideration of 120 day LoQ. As a candidate for the 150-day accelerated assessment, I think it may be possible that we get the EMA opinion quite soon - possibly before ASCO.... possibly tomorrow. If there is a strategy to withholding this news from public release, it evades me. Not quite the same as approval, but a necessary step in that direction. Just a thought...

  • wilderguide wilderguide 18 hours ago Flag

    $$$$
    Rationalizing the thoughts of others. Reaching out to others. Pressure's building...
    I feel a heal in' a'comin' on...

  • Reply to

    To Wilder

    by ulingt 20 hours ago
    wilderguide wilderguide 19 hours ago Flag

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    "Pals it is..."
    Well...it's good we got all that squared away - figured out who-all the adults were...figured out how to fix those of us that might be considered of lesser maturity...figured put how to fix the nation, cure a ravaged political system, rehabilitate a slew of deficient candidates -all the while educating the constituency...
    Nearly time to be getting back to the pleasures of exploring the potential of EXEL...isn't it?

  • wilderguide wilderguide 20 hours ago Flag

    $$$$
    Whose buttons did I push today...
    Doogie Hauser or Dear Abby...???

  • Reply to

    Nomad, jonesdexter, milkman, et al...

    by wilderguide May 28, 2016 12:05 PM
    wilderguide wilderguide May 29, 2016 2:47 PM Flag

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    "Don't tell me you are so stupid and gullible that you are actually considering voting..."
    It is America's greatest misfortune - and, as Americans - our misfortune as well... that the office of the president has so diminished in stature that it can no longer attract the type of statesman that is necessary to perform the essential task of leading a nation as large and diverse as ours has become. The embarassment of inviable presidential candidates speaks for itself, and if you believe that there is a capable leader amongst this years' candidates...you are every bit as incapable in your skills as a citizen as those in the running for our top office.
    Your mother must be very proud to call you her son...
    I cast my vote for beans & M-16s...

  • Reply to

    Nomad, jonesdexter, milkman, et al...

    by wilderguide May 28, 2016 12:05 PM
    wilderguide wilderguide May 29, 2016 12:02 PM Flag

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    Uli, it was all an attempt at humor. Sorry you don't get it.
    In the future, I'll stick to fact-based posts. Nothing that isn't in publication - nothing that isn't pertinent to EXEL. In fact, if it means we can be pals - I'll even vote for Hillary...give up my guns...give up my soul... But, I'm keepin' my testicles.
    A feller's gotta draw the line somewhere...

  • Reply to

    Nomad, jonesdexter, milkman, et al...

    by wilderguide May 28, 2016 12:05 PM
    wilderguide wilderguide May 29, 2016 7:39 AM Flag

    $$$$
    "Chill out wilder..."
    Just having fun...

  • Reply to

    Nomad, jonesdexter, milkman, et al...

    by wilderguide May 28, 2016 12:05 PM
    wilderguide wilderguide May 29, 2016 7:35 AM Flag

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    "what's your response?"
    In some cultures, tickling the hibernating bear is a mandate of spiritual passage. Apparently not so much in liberal white eastern cultures. Go ahead, vote for Hillary...hide behind her skirts...
    Perhaps she'll offer protection from heartless meanies like me...
    In return, she'll only want your guns, your political soul, and your testicles for earrings...

  • Reply to

    Nomad, jonesdexter, milkman, et al...

    by wilderguide May 28, 2016 12:05 PM
    wilderguide wilderguide May 28, 2016 7:55 PM Flag

    $$$$
    I mean...let me see if I can put this into words that might be more compatible with your powers of attentiveness, intellectuality, and interpretation. In the time-honored words of none-other than Fred Flintstone...
    It's almost "Yabba-Dabba-Doo Time"....and it really wouldn't be any fun unless we knew you were on board.
    Get my drift, Big Dog...?? Make an appearance - if only for all the good times we've shared...
    C'mon, you smarmy chatterbox...you can do it...you know you want to...it's who you are...
    Don't deny yourself the pleasure of another "Can't say you weren't warned..."

  • Reply to

    OT: Trivia for the day

    by erniewerner May 27, 2016 2:00 PM
    wilderguide wilderguide May 27, 2016 2:41 PM Flag

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    As the originator of the "Hindlick" Maneuver, I can attest to the good doctor's proclamation that it "feels wonderful to "save those girls.."... My greatest hope is that I can pursue relevancy into old age as has Dr. Heimlich.
    Without taking more than an occasional bite...

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    OncLive 5/25/16
    “Lenvatinib (Lenvima) plus everolimus (Afinitor) represents something that patients with heavily pretreated disease can potentially be approached with,” says Pal. “If a patient is fit enough to receive this regimen after having progressed on agents such as cabozantinib and nivolumab, it is a reasonable treatment option. It is always beneficial to have additional therapeutic options for these patients.”
    It will prove instructive to watch if/when L/E gets prescribed. The nature of the collaborative effort between pharmas, insurors, and oncodocs may lend insight to future Cabo combination support (ie Cabo plus Nivo) in the absence of formal partnering agreements. GLTA

  • Reply to

    Wilder, where are you?

    by joeflow77 May 25, 2016 10:58 PM
    wilderguide wilderguide May 26, 2016 9:54 AM Flag

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    "...we're all teed up."
    Short interest is climbing again. The struggle to keep a +$1B market cap is still with us. In recent times, this stock hasn't traded above $7/share except for AH. The converts are a bad fit in your success story.
    Like an elevator in an outhouse...

  • Reply to

    Wilder, where are you?

    by joeflow77 May 25, 2016 10:58 PM
    wilderguide wilderguide May 26, 2016 12:42 AM Flag

    $$$$
    "...don't you think it's a bit too soon to cash in ur trading shares?"
    Never too soon to take profit. No worries, I've got lots remaining...and if all goes well - will likely rebalance if EXEL should get above $8...perhaps again if it goes higher. I've traded EXEL for over 5 years - and, in all that time - it has proven a most fickle trade piece. In addition, I am as yet unconvinced that EXEL is out of the doghouse quite yet. Pay attention as this stock drifts toward $7 - the short volume will belie the convert strategy, particularly if MMM is slow in producing a debt restructuring plan...remains slow in providing a Celestial update...and stays slow in advancing Cabo into other indications. Shareholder value has not been the highest priority of this management team, and if that is shown to change, I may reconsider my strategy. Till then, I figure a low cost-basis is the place to be.

  • Reply to

    Wilder, where are you?

    by joeflow77 May 25, 2016 10:58 PM
    wilderguide wilderguide May 25, 2016 11:49 PM Flag

    $$$$
    Hangin' out grinnin' the wide grin...it's all good. Not much else to say till after ASCO, and whatever updates the EXEL investor's conference provides. Sold off my trading shares in EXEL this week, and feel confident with my core for the long term. We'll see...
    Spent this week looking hard at CRISPR stocks NTLA & EDIT - took small positions in each while I sort thru the differences in potential - and am self-tutoring in the proficiencies of CaS9 & Cpf1...and all the technobabble that goes along with constructively editing the gene code.
    It's a move I'd considered for some time, and the past month's improvement in EXEL gave me the wherewithal to redirect some funds. Best of luck to you, Joe - and in fact to you all. I don't know a group of more-deserving longs than you guys...each of you bears tribute to patience and perseverance equating prosperity.
    Congrats to all...

  • Reply to

    So here's our Analyst coverage (so far!)

    by captainhymanshocker May 23, 2016 12:16 PM
    wilderguide wilderguide May 25, 2016 1:49 PM Flag

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    "I have to say EXEL's prospects going forward look better than any time since before the Comet debacle."
    Amen to that. Been offline for a bit. Shill long here with a healthy core, but sold most of my trading position this week to look for a viable entry into CRISPR tech. Looks promising - landed a small position under $30 in NTLA...still looking at EDIT....and trying to differentiate potential between /CaS9 & /Cpf1. Lots of new stuff for me to digest. Congrats to all of us on recent CABOSUN news!

  • Reply to

    Mismatch repair demistified

    by erniewerner May 20, 2016 9:59 PM
    wilderguide wilderguide May 21, 2016 11:46 AM Flag

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    This concept makes me laugh...
    "Mismatch repair" sounds like a warranty offering from MatchDOTcom...
    "If your romantic match-up leads to spiteful, costly, heart-breaking divorce...
    We'll cheerfully refund your subscription fee..."

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    "Everyone knows why no one wants to be in the room with us." - Daniel Weiner, Turing lawyer...
    Most punchable face in America? Halitosis? B.O.? Sphincter stench?
    More on the Shkrelification of America from Reuters, 5/13/2016...

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    Taken from the research article,"Inhibition of the angiopoietin/Tie2 axis induces immunogenic modulation, which sensitizes human tumor cells to immune attack" Dec, 2015 - free at Research Gate...
    Grenga.. et al, in differentiating amongst sunitinib, sorafenib, and Cabo in modifying immune response:
    "Only one of these agents, cabozantinib, which is an inhibitor of multiple receptor tyrosine kinases, including RET, MET, and VEGRF2 has been reported to induce immunogenic modulation, altering tumor-cell phenotype and sensitizing tumor cells to immune-mediated attack." Very informative...
    Apparently, one of the Anna Kwilas NCI studies...Note that co-author Farsaci is employed by BMY...