Monday night, 7:15 pm, featured story (link) on Drudge Report is a fluffy piece about getting more exercise to ward off dementia. It's so predictable it's almost silly. Meanwhile, the real story of the day is ignored. Sooner or later this story will get the traction it deserves in the popular press. No later than March, that's for sure.
Thanks everyone for all the replies. I know this is a financial board, but every now and then a little perspective on the disease can't hurt. I know a lot of us are on, or have been down this same path.
Fortunately, I do get help from my mother, but she's 86, and she can only deal with so much. The other help I get is sporadic, but as things get more demanding, hopefully others will step up.
I was able to finally take a long planned, and many times delayed, cross-country train trip in early November. All the way from Boston to SoCal. I had a 6 day break out there, and then all the way back again. In addition to being a fantastic trip, it was SO good to get away for almost two weeks and not have to think about AD. I decided that if I'm going to keep my sanity, I HAD to get back out there for a little break every three months or so. So if PRAN jumps up just a little, I might even be able to do that.
Thanks narnia for the advice in finding the right medication to keep him calm. I have an appointment with his doctor to discuss that. I think if I could just get him to sleep regularly at night, so I can sleep regularly at night, the care-giving would be so much easier.
Thanks again everyone. And as many of you know, I think March will be a month to remember.
Thanks. This sounds just like my dad these days. Anyway, I got a little sleep, so did my dad. A few hours of peace.
Consider yourself lucky. I'm on 48 hours with 3 hours sleep. My dad has been agitated and delusional all night, so here I am, still awake at 4 am. No end in sight. I feel bad for him, but there's nothing that can be done. It's a cruel disease. Oddly enough, he can still play the piano, which is what he's doing right now, very loudly, at 4:11 am. Oh yeah, he's screwing around with the electrical outlet too. Did you know there's nothing but infomercials on at 4 a.m.? I think this could be classified as torture.
If PBT2 can prevent this for future AD patients and families, then it truly is God sent.
You just reminded me of one of the early signs with my dad. He always paid the electric bill, and for three months he missed it. That was unusual for him.
Same here too. Nobody is in a hurry to find out they're dealing with AD. And my dad was never one to want to go to a doctor. So we put it off for quite awhile. By the time I took him to the doctor, I didn't need the diagnosis. I already knew what we were dealing with.
Interesting about how fast your grandmother went downhill with AD. My dad was showing signs of it for at least six years, starting at about 80. Simple stuff at first, like forgetting to take the coffee cup out of the microwave. But he was still 'moderate' when tested a year or so ago. He's declining, but the rate seems rather slow, and his mother lived with dementia until 95. So I guess it varies.
My doctor did advise me to avoid hospitalizations if at all possible. Seek preventive care, that is. Apparently, an AD patient who has an episode of delirium while hospitalized has a significant chance of declining rapidly thereafter, and being dead within a year. Something to keep in mind.
Without question, the PBT2 group know they took PBT2. They know. For the placebo group, all they know is it didn't work.
So I agree with brewman totally. The doctors are not as close to the patients as the families, but they know what's going on at this point too. You REALLY, REALLY, REALLY should consider ...
I can read between the lines doc.
I have two degrees in chemistry and metal protein biochem is my forte. I'm intimately familiar with AD, as a family member has it. I know every detail and manifestation of the disease. I know that a family member is in an excellent position to judge the state of that disease in a patient.
So I've used my scientific background to judge the relative merits of the work of people like Tanzi and others. And I've use my first hand experience as an AD caregiver to evaluate the testimony of Patient Zero, and the retention rate of the extension trial. And I've followed PRAN for over three years, and have had plenty of time to do my DD on this company.
I'm guessing you're here for a quick buck and wouldn't know an enzyme from your own a hole. So make an easy buck or two here, and then go blow it out your a--.
Take a moment and think about just how big this is. An AD patient has taken PBT2 for between 2 and 14 months and has concluded that's it's a godsend. A miracle so to speak. His caregiver, intimately familiar with his personality, agrees that it's astonishing.
Between the retention rate in the extension trial, and this first-hand testimony, the data is speaking to us. Not officially, of course, but it's telling us something big. At this point, you would have to be blind not to get it.
PBT2 is likely the first effective treatment for AD!
How big is that? Here in Boston, we have a monument to the discovery of ether as a general anesthetic. No surprise, that advancement took place at the MGH. Imagine the pain and suffering that was alleviated with that simple (in retrospect) discovery.
Imagine how much pain and suffering will be avoided if the experience of Patient Zero translates to millions. The pain of AD doesn't begin with the cut of a surgeon's knife, and it isn't restricted to the patient on the table. It goes on and on for years, and deals as harsh a blow to the families and caregivers as it does to the patient. It's insidious and debilitating. It makes some of us live in fear of our own futures.
The unshakable science is telling my brain that they are putting the whole picture of AD together as never before. PBT2 may not be the only treatment for AD, but it will very likely be a part of it, and almost certainly be the first. The patients and their families are telling my gut that this is real.
And taken together, I have no doubt that medical history is being written. There won't be another chapter in medical history this important for another decade, at least. I won't be wrong. Count on it.
It was pretty damn exciting to pause the video and see PBT2 printed there. The wife knows the patient better than anyone, and her testimony is as good as it gets.
The first big hint was the participation rate in the extension. And now this. If I were a big pharma guy who was dismissive of the metals theory, I would be needing the 'heavy duty' depends about now.
Things are gonna get very interesting from here!
If we're a joke, how come everyone is laughing at you? You're comic relief on a stressful day. And when we're finished laughing, we simply ignore. See ya.