University of Pennsylvania Medication Safety Monitoring Program Places Additional Order for InforMedix's Med-eXpert System and Med-eMonitor Patient Appliances

268 Patients to Be Recruited Into Anticoagulation Health Safety-Monitoring Program

• Press Release
• Source: InforMedix
• On 8:52 am EST, Thursday December 4, 2008

ROCKVILLE, MD--(MARKET WIRE)--Dec 4, 2008 -- InforMedix Holdings, Inc. (OTC BB:IFMX.OB - News) ("InforMedix"), a leader in the development of sophisticated medication adherence management systems, announced that 268 patients will be monitored by InforMedix's Med-eXpert(TM) System and Med-eMonitor(TM) appliances through two specialty anticoagulation clinics at the University of Pennsylvania as part of an anticoagulation improvement research program. Med-eXpert provides critical intelligence on the medication adherence and health status of chronically ill outpatients, by capturing this information from patients using Med-ePhone(TM) and Med-eMonitor patient appliances, and providing instant alerts if patients miss medication or their health is declining. This program represents the fifth order of Med-eXpert System monitoring and Med-eMonitor appliances by the University of Pennsylvania Health System.

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"This novel, rewards-based program uses incentives including a lottery system and reminder systems managed by our Med-eXpert System, to reward patients who adhere properly to their medications and has already been used in 120 patients at Penn who are currently taking anticoagulant medication," said Bruce A. Kehr, M.D., InforMedix's Chairman and Chief Executive Officer. "This 'blood thinner' medication is used to prevent blood clots from forming in the body that cause life-threatening strokes and pulmonary embolism (an often fatal blood clot in the lungs). Taking too little medication results in increased incidence of stroke and pulmonary embolism, while taking too much medication may cause life-threatening excessive bleeding."

Every 42 seconds in the United States, someone experiences a stroke. This fact translates into approximately 760,000 new or recurrent strokes in the United States each year. It is the second leading cause of mortality in the world after cardiovascular disease, the third leading cause of death in the United States, and is the leading cause of long-term disability. The annual cost of stroke related care in the U.S. was projected to exceed $58 billion in 2006. (Medscape Neurology & Neurosurgery 3(1), 2001. Managed Healthcare Executive, April 1, 2006, and the American Stroke Association (ASA).)

The Penn researchers include: Kevin Volpp, M.D., Ph.D., Director of the Leonard Davis Institute of Health Economics Center for Health Incentives and Associate Professor of Medicine and Health Care Management, University of Pennsylvania School of Medicine and the Wharton School; and Stephen E. Kimmel, M.D., M.S.C.E., Director, Cardiovascular Epidemiology, and Associate Professor of Medicine & Epidemiology, University of Pennsylvania School of Medicine.

About InforMedix

InforMedix is the source and repository of critical intelligence around how individuals are adhering to their prescribed medication and care plans. InforMedix provides its patented Med-eXpert(TM) information system providing real-time, customizable and actionable information on the medication adherence and health status of chronically ill outpatients. Two portable appliances are used by patients to follow their medication and care plans, and to record and transmit medication adherence and health status information to the Med-eXpert System. The Med-eMonitor(TM), a portable, interactive, "smart pillbox," which stores and/or manages up to 25 medications, while tracking patients' adherence to their medications and care plans, and The Med-ePhone(TM), which prompts, monitors and records medication adherence and health status assessment delivered to patients over mobile phones and landlines using Interactive Voice Response Systems (IVRS). Mission-critical information can be uniquely customized for each customer's and patient's needs at both individual and population levels to more effectively and efficiently reduce healthcare costs, improve health outcomes and increase patient satisfaction. InforMedix Solutions consistently achieve medication and care plan adherence rates of 90% or more across multiple chronic disease populations, as documented by academic medical center trials and peer-reviewed journal articles. For more information, visit http://www.informedix.com

Safe Harbor Statement

This press release may contain forward-looking statements that involve risks and uncertainties, including statements regarding our business strategy and development plans, plans for entering into new businesses, anticipated sources and uses of funds and other statements regarding our plans, objectives, expectations and intentions that are not historical facts. Because these forward-looking statements involve risks and uncertainties, actual results could differ materially from those discussed in this press release. These risks and uncertainties are described in greater detail in the reports that we file with the Securities and Exchange Commission. Our actual results, performance or achievements may vary materially from those expressed or implied in any forward-looking statements. All forward-looking statements reflect our beliefs and expectations as of the date of this press release and should not be relied upon as representing our views as of any subsequent date. While we may elect to update these forward-looking statements publicly at some point in the future, we specifically disclaim any obligation to do so, whether as a result of new information, future events or otherwise.

     Media Contacts:
     Bruce A. Kehr, M.D.
     InforMedix
     Phone: (301)-984-1566 ext. 101
     Email Contact