WINNIPEG, MANITOBA--(Marketwire - Oct 1, 2012) - Kane Biotech Inc. (TSX VENTURE:KNE), a biotechnology company engaged in the development and commercialization of products that prevent and remove microbial biofilms announces that a Cooperative Research and Development Agreement (CRADA) has just been signed with the U.S. Army Institute of Surgical Research (USAISR) in Fort Sam Houston, Texas. This agreement replaces the original agreement that was previously signed with the Walter Reed Army Institute of Research.
The primary objective of this collaboration on "Treatments to Prevent Biofilm Formation for Promoting Wound Healing" is to develop an antibiofilm-antimicrobial wound gel formulation and test the said gel formulation to address the needs of the United States Army Dental and Trauma Research Detachment''s (USADTRD) programs and that can be readily translated into clinical testing for improving the outcomes of wounded casualties. The collaboration includes conducting research using wound infections to test the efficacy of the wound gel containing antimicrobial peptide KSL-W and DispersinB® antibiofilm enzyme in killing biofilm-embedded bacteria by disrupting biofilms formed on the wound surface.
The mission of the United States Army Dental and Trauma Research Detachment (USADTRD) is to provide military relevant research and solutions to treat and rehabilitate craniomaxillofacial trauma and prevent infectious disease. The USADTRD''s Biofilm Impaired Wound Healing program focuses on providing algorithms to understand biofilm pathophysiology and test agents useful to treat not only dental biofilm (plaque) and combat wounds-associated biofilm infections, but also to provide antimicrobials for the control of dental plaque-associated oral infections.
About Kane Biotech Inc.
Kane Biotech is a biotechnology company engaged in the development and commercialization of products to prevent and remove biofilms. Biofilms are a major cause of a number of serious medical problems including chronic infections and medical device related infections. They develop on surfaces such as catheters, prosthetic implants, teeth, lungs and the urogenital tract. Biofilms are pervasive, costly to deal with and are involved in approximately 80% of all human bacterial infections. The healing of chronic wounds alone costs the United States health care system $20 billion per year.
Kane Biotech uses patent protected technologies based on molecular mechanisms of biofilm formation/dispersal and methods for finding compounds that inhibit or disrupt biofilms. The Company has evidence that these technologies have potential to significantly improve the ability to prevent and/or destroy biofilms in several medical and industrial applications.
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