Large cap ETFs are the most popular of all categories, but often they are taken for granted. While differences between funds are mostly subtle, the sheer amount of money placed in these ETFs makes it prudent to understand them.Plain vanilla, low-cost S&P 500 ETFs are where many investors park the core of their stock portfolio before they shop for satellite ETFs. SPDR S&P 500 (AMEX:SPY - News) handles an astounding $66 Billion, while iShares S&P 500 ETF (NYSEArca:IVV - News) runs $18 Billion. These two funds alone normally account for over 10% of all ETF assets. Both charge a paltry 0.09% in annual fees.There are minor differences between how the funds operate. SPY pays dividends quarterly while IVV pays bi-annually. The funds navigate index composition changes differently. SPY's spectacular economies of scale drive bid-ask spreads down to minute levels, but IVV's are also impressive. We see no obvious evidence of superiority of one fund over the other.The main decision by large cap investors is where to drawn the line on size, as there are several alternatives to the S&P 500 format. One alternative is with the largest 750 US stocks such as found in Vanguard's Large Cap ETF (AMEX:VV - News), with 0.12% fees. It follows the MSCI US Prime Market 750 Index, which throws smaller companies into the mix but still remains arguably large cap. Its main attraction is avoiding fallout from additions and deletions which can affect the popular S&P 500. When a company is added or deleted from the S&P 500, its stock can swing several percentage points up or down. This is always to the detriment of index funds which must sell the losers and buy the winners. Arbitrageurs commonly jump ahead of them and drive prices further even away.Competing with VV is the SPDR Dow Jones Wilshire Large Cap ETF (AMEX:ELR - News), whose DJ Wilshire Large Cap Index also follows about 750 companies at 0.23% annual cost.Despite all the theoretical differences, actual returns are highly correlated in practice:

- PowerShares Dynamic Large Cap Growth Portfolio ETF (AMEX: PWB - News); 0.6% annual fees
- PowerShares Dynamic Large Cap Portfolio ETF (AMEX:PJF - News); 0.6% annual fees
- PowerShares Dynamic Large Cap Value ETF (AMEX:PWV - News); 0.6% annual fees
- RevenueShares Large Cap ETF (NYSEArca:RWL - News); 0.54% fees
- WisdomTree LargeCap Dividend ETF (NYSEArca :DLN - News); 0.28% fees
- ELEMENTS SPECTRUM Large Cap US Sector ETN (NYSEArca:EEH - News); 0.75% fees
- First Trust Large Cap Core AlphaDEX ETF (NYSEArca:FEX - News); 0.7% fees
- SPDR Dow Jones Wilshire Large Cap Growth ETF (AMEX:ELG - News); 0.2% fees
- SPDR Dow Jones Wilshire Large Cap Value ETF (AMEX:ELV - News); 0.2% fees
- iShares Morningstar Large Core ETF (NYSEArca:JKD - News); 0.2% fees
- iShares Morningstar Large Growth ETF (NYSEArca:JKE - News); 0.25% fees
- iShares Morningstar Large Value ETF (NYSEArca:JKF - News); 0.25% fees
- Then there are ETFs which combine fundamental and style investing:
- Claymore Great Companies Large-Cap Growth ETF (AMEX:XGC - News); 0.6%
- ELEMENTS Benjamin Graham Large Cap Value Total Return ETN (NYSEArca:BVL - News); 0.75%
- First Trust Large Cap Growth Opportunities AlphaDEX ETF (NYSEArca:FTC - News); 0.7%
- First Trust Large Cap Value Opportunities AlphaDEX ETF (NYSEArca:FTA - News); 0.7%
- Grail American Beacon Large Cap Value ETF (NYSEArca:GVT - News); 0.79%
- Wisdom Tree Large Cap Growth ETF (NYSEArca: ROI - News); 0.38%

