WINNIPEG, MANITOBA--(Marketwired - April 4, 2013) - Kane Biotech Inc. (TSX VENTURE:KNE), is pleased to report that in a recently completed dog efficacy field study, StrixNB was very effective against halitosis (bad breath). The study was conducted on Sheltie dogs. Kane Biotech is a biotechnology company engaged in the development and commercialization of products that prevent and remove microbial biofilms.
The field study was designed to evaluate the effect of StrixNB on bad breath in dogs over a period of 21 days using a Halimeter® to measure the Volatile Sulfur Compounds (VSC) in breath samples. Five Sheltie dogs ranging in age from 2 years to 14 years were used in the study and had varying degrees of bad breath from slight odor to very strong odor. The dogs were kept on the same diet and drinking water with StrixNB added to the drinking water from Day 0 after measuring the initial VSC in their breath.
The VSC measurements were taken 8 times between Day 0 and Day 21 of the study. Dogs with the highest VSC measurements (very strong odor) showed the greatest reduction in bad breath. Day 9 of the study showed a reduction of 50% to 69% in the dogs with the strong odor. After 21 days, the VSC reduction continued to improve to 71% to 82%. The remaining dogs that had no or slight odor also showed VSC reductions but the percentage was lower as the base line was normal. Improvements were recorded in all five dogs with an average reduction of 48%. The level of VSC or halitosis is a strong diagnostic predictor of periodontal disease.
The Halimeter measurements of VSC levels were also compared with the organoleptic assessment of bad breath using judges. There was also a correlation between organoleptic scoring of bad breath and the Halimeter measurement of VSC. Thus, both the methods of measuring bad breath show that StrixNB is very effective against bad breath in dogs.
"Doggie breath has always been a challenge that pet owners have with their dogs and StrixNB is a unique product that attacks the problem head on," stated Gord Froehlich, President and CEO of Kane Biotech. "We have received numerous compliments on StrixNB's breath freshening effect and are excited StrixNB will soon be available to pet owners across Western Canada through their local Veterinary Clinics."
In addition to the measurement of bad breath, other observations in the test animals included a noticeable change in the teeth and gum line in the dogs with very strong bad breath and plaque had started to soften and was easily removable.
StrixNB is a safe and effective drinking water additive to help maintain and promote good dental and oral hygiene for companion animals. StrixNB is xylitol-free, made using 100% human food grade ingredients and registered with the Interim Notification Program of Health Canada for Low Risk Veterinary Health Products (NN.1Q11).
StrixNB works against dental disease-associated bacteria by altering the mouth's environment. It breaks through dental biofilm - a highly structured, matrix-embedded microbial population - leaving bacteria otherwise inaccessible exposed for eradication by a microbial agent.
About Kane Biotech Inc.
Kane Biotech is a biotechnology company engaged in the development and commercialization of products that prevent and remove biofilms. Biofilms develop when bacteria and other microorganisms form a protective matrix that acts as a shield against attack. When in a biofilm, bacteria become highly resistant to antibiotics, biocides, disinfectants, high temperatures and host immune responses. This resiliency contributes to human health problems such as recurrent urinary tract infections, medical device associated infections and tooth decay.
Kane Biotech uses patent protected technologies based on molecular mechanisms of biofilm formation/dispersal and methods for finding compounds that inhibit or disrupt biofilms. The Company has evidence that these technologies have potential to significantly improve the ability to prevent and/or destroy biofilms in several medical and industrial applications.
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StrixNB™, DispersinB® and Aledex® are registered trademarks of Kane Biotech Inc. All Rights Reserved 2013.