| UPGRADES & DOWNGRADES HISTORY |
| Date | Research Firm | Action | From | To | | 11-Dec-07 | Piper Jaffray | Initiated | | Buy | | 11-Dec-07 | Credit Suisse | Initiated | | Outperform | | 11-Dec-07 | Leerink Swann | Initiated | | Outperform | | 11-Dec-07 | Fox Pitt | Initiated | | Outperform |
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| Current Month | Last Month | Two Months Ago | Three Months Ago | | Strong Buy | 2 | 2 | 2 | 2 | | Buy | 1 | 1 | 1 | 1 | | Hold | 1 | 1 | 1 | 1 | | Underperform | 0 | 0 | 0 | 0 | | Sell | 0 | 0 | 0 | 0 |
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