| UPGRADES & DOWNGRADES HISTORY |
| Date | Research Firm | Action | From | To | | 13-Nov-08 | Wasserman & Associates | Initiated | | Buy | | 11-Nov-08 | Leerink Swann | Initiated | | Underperform | | 7-Nov-08 | Dougherty & Company | Downgrade | Buy | Neutral | | 2-Oct-08 | Morgan Keegan | Downgrade | Outperform | Mkt Perform | | 28-Aug-08 | Argus | Downgrade | Buy | Hold | | 17-Jun-08 | Dougherty & Company | Initiated | | Buy | | 16-Jun-08 | Dougherty & Company | Initiated | | | | 9-May-08 | RBC Capital Mkts | Downgrade | Top Pick | Outperform | | 29-Apr-08 | Citigroup | Initiated | | Buy | | 19-Oct-07 | Deutsche Securities | Initiated | | Hold |
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| Current Month | Last Month | Two Months Ago | Three Months Ago | | Strong Buy | | | | | | Buy | | | | | | Hold | | | | | | Underperform | | | | | | Sell | | | | |
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