| Date | Event |
| 4-Dec-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |
| 27-Nov-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |
| 16-Nov-09 | Shire Plc downgraded by Caris & Company |
| 13-Nov-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |
| 6-Nov-09 | SHIRE PLC Files SEC form 10-Q, Quarterly Report |
| 4-Nov-09 | SHIRE PLC Files SEC form 8-K, Change in Directors or Principal Officers, Financial Statements and Exhibits |
| 4-Nov-09 | SHIRE PLC Files SEC form 8-K, Change in Directors or Principal Officers, Financial Statements and Exhibits |
| 30-Oct-09 | SHIRE PLC Files SEC form 8-K, Results of Operations and Financial Condition, Financial Statements and Exhibits |
| 30-Oct-09 | Price hit new 52-week high ($54.06) |
| 28-Oct-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |
| 28-Oct-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |
| 19-Oct-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |
| 5-Oct-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |
| 29-Sep-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |
| 24-Sep-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |
| 22-Sep-09 | Price hit new 52-week high ($53.85) |
| 18-Sep-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |
| 17-Sep-09 | Price hit new 52-week high ($53.15) |
| 9-Sep-09 | Ex-Date for dividend payment of $0.064 |
| 8-Sep-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |
| 8-Sep-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |
| 4-Sep-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |
| 3-Sep-09 | SHIRE PLC Files SEC form 8-K, Other Events, Financial Statements and Exhibits |
| 3-Sep-09 | SHIRE PLC Files SEC form 8-K, Other Events, Financial Statements and Exhibits |
| 1-Sep-09 | SHIRE PLC Files SEC form 8-K, Other Events, Financial Statements and Exhibits |
| 1-Sep-09 | SHIRE PLC Files SEC form 8-K, Other Events, Financial Statements and Exhibits |
| 19-Aug-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |
| 7-Aug-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |
| 6-Aug-09 | SHIRE PLC Files SEC form 10-Q, Quarterly Report |
| 5-Aug-09 | SHIRE PLC Files SEC form 8-K, Results of Operations and Financial Condition, Financial Statements and Exhibits |
| 4-Aug-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |
| 28-Jul-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |
| 21-Jul-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |
| 17-Jul-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |
| 10-Jul-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |
| 7-Jul-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |
| 1-Jul-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |
| 1-Jun-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |
| 27-May-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |
| 22-May-09 | SHIRE PLC Files SEC form 8-K, Financial Statements and Exhibits |