| Individual/Entity | Most Recent Trans. | Shares Owned as of Trans. Date | CHA ALBERT
Director | Sale
12-Feb-08 | 1,553,632
12-Feb-08 | GINSBERG BARRY H
Director | Purchase
25-Sep-08 | 5,700
25-Sep-08 | GREAT POINT PARTNERS I LP
Beneficial Owner (10% or more) | Automatic Sale
17-Aug-09 | 1,453,918
17-Aug-09 | KRASNER ALAN SETH
Officer | Option Exercise
9-Nov-09 | 3,100
9-Nov-09 | KROIN DAVID
Director | Automatic Sale
21-Oct-09 | 3,053,107
21-Oct-09 | ORBIMED ADVISORS LLC
Director | Sale
10-Jun-09 | 1,485,904
10-Jun-09 | PEREIRA BRIAN JG
Director | Disposition (Non Open Market)
12-Feb-08 | 60,000
12-Feb-08 | PFUTZNER ANDREAS
Officer | Purchase
6-Nov-08 | 2,000
6-Nov-08 | POHL RODERIKE
Officer | Automatic Sale
8-Oct-08 | 192,418
8-Oct-08 | STEINER SOLOMON
Officer | Sale
12-Feb-08 | 4,111,899
12-Feb-08 | STEINER VENTURES LLC
Beneficial Owner (10% or more) | Sale
12-Feb-08 | 4,044,266
12-Feb-08 | WARE R TIMMIS
Officer | Option Exercise
17-Apr-08 | 92,471
17-Apr-08 | WEISMAN SCOTT
Director | Automatic Sale
19-Oct-09 | 360,636
19-Oct-09 | WERTHEIMER SAMUEL P
Director | Sale
10-Jun-09 | 1,485,904
10-Jun-09 |
|
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