| Individual/Entity | Most Recent Trans. | Shares Owned as of Trans. Date |
|---|
AISLING CAPITAL II LP Beneficial Owner (10% or more) | Purchase Feb 6, 2012 | 3,293,060
Feb 6, 2012 | FERNANDES PRABHAVATHI Officer | Ownership Statement Feb 1, 2012 | 203,684 Feb 1, 2012 | GILL DAVID N Director | Ownership Statement Mar 31, 2012 | 0 Mar 31, 2012 | GOLDSTEIN DOV A MD Director | Purchase Feb 6, 2012 | 3,293,060
Feb 6, 2012 | HAHN MARK W Officer | Ownership Statement Feb 1, 2012 | 0 Feb 1, 2012 | INTERSOUTH ASSOCIATES VI, LLC Beneficial Owner (10% or more) | Purchase Feb 7, 2012 | 1,970,729
Feb 7, 2012 | JOHNSON JOHN Director | Ownership Statement Feb 1, 2012 | 0 Feb 1, 2012 | KENT RICHARD S Director | Ownership Statement Feb 1, 2012 | 1,482,070
Feb 1, 2012 | KONG GARHENG Director | Ownership Statement Feb 1, 2012 | 0 Feb 1, 2012 | MORRIS I WISTAR III Beneficial Owner (10% or more) | Option Exercise Aug 16, 2012 | 1,262,099 Aug 16, 2012 | NEFF P SHERRILL Director | Purchase Feb 7, 2012 | 3,262,154
Feb 7, 2012 |
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