| Individual/Entity | Most Recent Trans. | Shares Owned as of Trans. Date | BANK OF AMERICA CORP /DE/ Director | Disposition (Non Open Market) 26-Aug-08 | 1,318,535 26-Aug-08 | BANK OF AMERICA VENTURES Beneficial Owner (10% or more) | Sale 30-Jan-08 | 364,742 30-Jan-08 | BESSEMER VENTURE PARTNERS IV LP Beneficial Owner (10% or more) | Sale 30-Jan-08 | 41,015 30-Jan-08 | CB HEALTHCARE FUND LP Beneficial Owner (10% or more) | Sale 30-Jan-08 | 1,148,546 30-Jan-08 | COOPER THOMAS P Director | Option Exercise 4-Nov-09 | 3,461 4-Nov-09 | MORGENTHALER PARTNERS VII LP Beneficial Owner (10% or more) | Sale 21-Jul-08 | 389,108 21-Jul-08 | MORGENTHALER VENTURE PARTNERS IV Beneficial Owner (10% or more) | Sale 21-Jul-08 | 870,943 21-Jul-08 | RUSSELL RICHARD G Officer | Automatic Sale 20-Oct-09 | 22,169 20-Oct-09 | SARRIA FERNANDO Officer | Option Exercise 3-Dec-09 | 1,500 3-Dec-09 | SHAPIRO DEVRA G Officer | Automatic Sale 29-May-09 | 98,512
29-May-09 | SINGER ADAM D MD Officer | Automatic Sale 1-Dec-09 | 267,506 1-Dec-09 | SMITH BARRY M Director | Option Exercise 6-Jun-08 | 28,045 6-Jun-08 | SMITH TOM Director | Ownership Statement 24-Jan-08 | 23,535
24-Jan-08 | TAYLOR R JEFFREY Officer | Sale 10-Aug-09 | 143,558 10-Aug-09 | TIMPE CHUCK Director | Sale 10-Sep-09 | 24,194 10-Sep-09 |
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