| Individual/Entity | Most Recent Trans. | Shares Owned as of Trans. Date | 14159 CAPITAL (GP), LLC
Beneficial Owner (10% or more) | Purchase
21-May-09 | 187,572
21-May-09 | BAKER / TISCH CAPITAL (GP), LLC
Beneficial Owner (10% or more) | Purchase
21-May-09 | 84,425
21-May-09 | BAKER BIOTECH CAPITAL (GP), LLC
Beneficial Owner (10% or more) | Ownership Statement
6-May-09 | 1,893,795
6-May-09 | BAKER BROS. CAPITAL (GP), LLC
Beneficial Owner (10% or more) | Purchase
21-May-09 | 105,798
21-May-09 | BAKER BROTHERS LIFE SCIENCES CAPITAL (GP), LLC
Beneficial Owner (10% or more) | Purchase
21-May-09 | 7,134,387
21-May-09 | BROOM COLIN MD
Officer | Option Exercise
12-Sep-08 | 12,103
12-Sep-08 | CLAYPOOL WILLIAM D MD
Director | Purchase
27-Feb-09 | 60,000
27-Feb-09 | DE ROSEN MICHEL
Director | Sale
10-Nov-08 | 137,100
10-Nov-08 | DOUGHERTY MICHAEL R
Director | Option Exercise
3-Nov-08 | 0
3-Nov-08 | DOYLE THOMAS F
Officer | Purchase
27-Feb-09 | 50,807
27-Feb-09 | GLASER ROBERT
Director | Acquisition (Non Open Market)
27-Feb-09 | 41,860
27-Feb-09 | MILANO VINCENT
Officer | Purchase
27-Feb-09 | 66,367
27-Feb-09 | MORRIS RICHARD STEVEN
Officer | Sale
11-Sep-08 | 392
11-Sep-08 | ROWLAND CHARLES A JR
Officer | Purchase
26-Feb-09 | 24,000
26-Feb-09 | SOLAND DANIEL B
Officer | Purchase
12-Mar-09 | 70,000
12-Mar-09 |
|
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