| Individual/Entity | Most Recent Trans. | Shares Owned as of Trans. Date | BURLINGAME ASSET MANAGEMENT, LLC Beneficial Owner (10% or more) | Purchase 29-Oct-09 | 875,435 29-Oct-09 | BVF ACQUISITION LLC Other | Ownership Statement 23-Jan-09 | 0 23-Jan-09 | BVF PARTNERS L P/IL Beneficial Owner (10% or more) | Sale 18-Nov-09 | 16,147,204 18-Nov-09 | COPPEDGE ROBERT M Other | Ownership Statement 9-Jan-09 | 0 9-Jan-09 | HOROVITZ ZOLA P Director | Sale 19-Nov-09 | 0 19-Nov-09 | IWAKI YUICHI Director | Sale 5-May-08 | 0
5-May-08 | LAMPERT MARK N Beneficial Owner (10% or more) | Ownership Statement 9-Jan-09 | 4,969,764
9-Jan-09 | NODELMAN OLEG Other | Ownership Statement 9-Jan-09 | 0 9-Jan-09 | PERRY MATTHEW D Other | Ownership Statement 9-Jan-09 | 0 9-Jan-09 | PRENDERGAST JOHN K A Director | Sale 14-Aug-08 | 39,108 14-Aug-08 | SOUTHPAW CREDIT OPPORTUNITY MASTER FUND, L.P. Beneficial Owner (10% or more) | Purchase 21-Oct-09 | 4,884,508
21-Oct-09 |
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