| Individual/Entity | Most Recent Trans. | Shares Owned as of Trans. Date | ABERDARE VENTURES II, L.P.
Beneficial Owner (10% or more) | Purchase
24-Feb-09 | 1,720,467
24-Feb-09 | BAY CITY CAPITAL LLC
Beneficial Owner (10% or more) | Purchase
19-Feb-09 | 4,337,102
19-Feb-09 | EVNIN LUKE
Director | Purchase
24-Feb-09 | 5,790,841
24-Feb-09 | GADICKE ANSBERT
Beneficial Owner (10% or more) | Purchase
24-Feb-09 | 5,790,841
24-Feb-09 | GOLDFISCHER CARL
Director | Purchase
19-Feb-09 | 4,337,102
19-Feb-09 | GRIFFIN BOBBY IVAN
Director | Purchase
24-Feb-09 | 329,755
24-Feb-09 | HARRISON DONALD C
Director | Purchase
5-Feb-09 | 27,927
5-Feb-09 | HUDSON BAY CAPITAL MANAGEMENT, L.P.
Beneficial Owner (10% or more) | Sale
5-Oct-09 | 3,729,965
5-Oct-09 | KLINGENSTEIN PAUL H
Director | Purchase
24-Feb-09 | 1,720,467
24-Feb-09 | KNUDSON MARK B
Officer | Purchase
24-Feb-09 | 195,421
24-Feb-09 | KOSKINAS ELLEN E
Director | Purchase
24-Feb-09 | 2,225,163
24-Feb-09 | LEA GREGORY S
Officer | Purchase
24-Feb-09 | 19,495
24-Feb-09 | MPM BIOVENTURES III QP LP
Beneficial Owner (10% or more) | Purchase
24-Feb-09 | 5,790,841
24-Feb-09 | TREMMEL JON T
Director | Ownership Statement
28-Jan-09 | 6,156
28-Jan-09 |
|
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