| Individual/Entity | Most Recent Trans. | Shares Owned as of Trans. Date | BROWN ROBERT S.
Officer | Acquisition (Non Open Market)
3-Mar-10 | 92,665
3-Mar-10 | BURBANK JEFFREY H
Officer | Acquisition (Non Open Market)
3-Mar-10 | 701,815
3-Mar-10 | CHAMBON PHILIPPE
Director | Acquisition (Non Open Market)
31-Dec-09 | 31,595
31-Dec-09 | CREDIT SUISSE AG/
Beneficial Owner (10% or more) | Purchase
1-Aug-08 | 7,208,096
1-Aug-08 | FLYNN JAMES E
Beneficial Owner (10% or more) | Sale
15-Dec-09 | 733,647
15-Dec-09 | GIANNINI DANIEL A
Director | Acquisition (Non Open Market)
31-Dec-09 | 24,625
31-Dec-09 | LEWIS EARL R
Director | Option Exercise
1-Mar-10 | 47,166
1-Mar-10 | MOORE CRAIG W
Director | Acquisition (Non Open Market)
31-Dec-09 | 41,999
31-Dec-09 | ORBIMED ADVISORS LLC
Director | Purchase
26-Aug-08 | 5,718,256
26-Aug-08 | PHILDIUS PETER P
Director | Sale
21-Aug-08 | 3,642
21-Aug-08 | REID PERPER
Director | Acquisition (Non Open Market)
31-Dec-09 | 189,393
31-Dec-09 | SHEA THOMAS
Officer | Acquisition (Non Open Market)
3-Mar-10 | 59,669
3-Mar-10 | SILVERSTEIN JONATHAN
Director | Ownership Statement
23-Jul-08 | 5,555,556
23-Jul-08 | SWAN WINIFRED L
Officer | Acquisition (Non Open Market)
3-Mar-10 | 100,462
3-Mar-10 | TURK JOSEPH E JR
Officer | Sale
16-Mar-10 | 175,725
16-Mar-10 | UTTERBERG DAVID S
Director | Sale
16-Mar-10 | 8,435,309
16-Mar-10 | WEBB MICHAEL J.
Officer | Option Exercise
9-Mar-10 | 58,877
9-Mar-10 |
|
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