| Individual/Entity | Most Recent Trans. | Shares Owned as of Trans. Date | BARRETT M JAMES
Director | Acquisition (Non Open Market)
17-Jan-08 | 4,563,512
17-Jan-08 | BARRIS PETER J
Beneficial Owner (10% or more) | Acquisition (Non Open Market)
17-Jan-08 | 4,563,512
17-Jan-08 | BENCHERIF MEROUANE
Officer | Option Exercise
28-Jul-09 | 7,735
28-Jul-09 | BRENNAN JEFFREY P
Officer | Option Exercise
20-Oct-09 | 0
20-Oct-09 | BROWN JULIA R
Director | Purchase
17-Mar-09 | 7,500
17-Mar-09 | BVF PARTNERS L P/IL
Beneficial Owner (10% or more) | Sale
16-Oct-09 | 3,640,725
16-Oct-09 | CALDWELL WILLIAM S
Officer | Option Exercise
4-Sep-09 | 7,735
4-Sep-09 | DEBETHIZY J DONALD
Officer | Option Exercise
8-Sep-09 | 46,917
8-Sep-09 | DUNBAR GEOFFREY C
Officer | Option Exercise
18-Sep-09 | 23,755
18-Sep-09 | KRAMLICH C RICHARD
Beneficial Owner (10% or more) | Acquisition (Non Open Market)
17-Jan-08 | 4,563,512
17-Jan-08 | MUSSO ALAN A
Officer | Option Exercise
4-Sep-09 | 2,799
4-Sep-09 | NEA PARTNERS 10 L P
Beneficial Owner (10% or more) | Acquisition (Non Open Market)
17-Jan-08 | 4,563,512
17-Jan-08 | NEW ENTERPRISE ASSOCIATES 10 L P
Beneficial Owner (10% or more) | Acquisition (Non Open Market)
17-Jan-08 | 4,563,512
17-Jan-08 | NEWHALL CHARLES W III
Beneficial Owner (10% or more) | Acquisition (Non Open Market)
17-Jan-08 | 4,563,512
17-Jan-08 | PERRY MARK W
Beneficial Owner (10% or more) | Acquisition (Non Open Market)
17-Jan-08 | 4,563,512
17-Jan-08 | SANDELL SCOTT D
Beneficial Owner (10% or more) | Acquisition (Non Open Market)
17-Jan-08 | 4,563,512
17-Jan-08 | TRAINOR III EUGENE A
Beneficial Owner (10% or more) | Acquisition (Non Open Market)
17-Jan-08 | 4,563,512
17-Jan-08 | ZORN PETER A
Officer | Option Exercise
22-Oct-09 | 0
22-Oct-09 |
|
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